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FLASH GENE

Symbol

GOT2

contributors: mct - updated : 08-10-2019

HGNC name	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
HGNC id	4433

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

EIEE82

related resource

MITOP database

Susceptibility

to cardiovascular disease and metabolic syndrome (MetS)

Variant & Polymorphism SNP	rs6993 located in the 3 prime untranslated region of the GOT2 locus was significantly associated with features of the MetS, including arterial hypertension

Candidate gene
Marker	can serve as an independent prognostic factor for overall survival and disease-free survival of patients with breast cancer, especially triple-negative breast cancer
Therapy target

ANIMAL & CELL MODELS