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FLASH GENE
Symbol SLC6A15 contributors: npt/ - updated : 23-08-2007
HGNC name solute carrier family 6 (neutral amino acid transporter), member 15
HGNC id 13621
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • putative twelve membrane-spanning domains
  • five potential N-linked extracellular glycosylation sites
    • HOMOLOGY
    interspecies homolog to rattus V7.3
    Homologene
    FAMILY
  • neurotransmitter symporter family (SNF)
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in neurotransmitter transport
  • involved in the transport of branched-chain amino acids, particularly leucine, that may be an important source of amino nitrogen for neurotransmitter synthesis in glutamatergic and GABAergic neurons
  • may have minor roles in synaptosomal proline uptake, leucine uptake and behaviors (Drgonova 2007)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS