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FLASH GENE
Symbol GPR83 contributors: mct/npt - updated : 06-04-2010
HGNC name G protein-coupled receptor 83
HGNC id 4523
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments (7TM)
  • HOMOLOGY
    intraspecies homolog to NPT2R
    Homologene
    FAMILY
  • rhodopsin family
  • G-protein coupled receptor 1 family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • orphan receptor potentially neuropeptide y receptor,
  • may be involved in control of emotions and of neuroendocrine, cognitive and motor functions
  • having function directly responsive to glucocorticoid signals (Sah 2005)
  • potential role in the control of feeding and ingestive behavior, regulation of stress and emotional behavior, learning and memory, and, drug reinforcement and reward (Sah 2005)
  • dispensable for regulatory T (Treg) cells development and function (Lu 2007)
  • might be critically involved in the peripheral generation of Foxp3+regulatory T cells (Hansen 2006)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS