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	HGNC	UniGene	Nucleotide		OMIM	UCSC

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FLASH GENE

Symbol

MEG3

contributors: mct/npt - updated : 22-04-2015

HGNC name	maternally expressed 3 (non-protein coding)
HGNC id	14575

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

UPD14M , UPD14P

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   biallelic expression in cancer tumoral         loss of expression in tumors tumoral     --low   by hypermethylation in acute myeloid leukemia and myelodysplastic syndromes with worse overall prognosis (Benetatos 2010) tumoral     --low   could promote the proliferative and invasive abilities of hepatoma cells and accelerate cell cycle

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS