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FLASH GENE

Symbol

TSPAN32

contributors: npt - updated : 18-11-2003

HGNC name	tetraspanin 32
HGNC id	13410

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain         Respiratory lung

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic         Lymphoid

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic leukocyte Lymphoid/Immune B cell

cell lineage	hematopoietic cell lineage
cell lines
fluid/secretion

at STAGE

physiological period

fetal

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	four hydrophobic regions
	an N terminal cytoplasmic domain
	a transmembrane domain
	a several potential phosphorylations sites

HOMOLOGY

interspecies

ortholog to murine Phemx

intraspecies

homolog to CD81

Homologene

FAMILY

tetraspanin (TM4SF) family

CATEGORY

tumor suppressor , signaling

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

may be playing a role in malignancies and disease that involve this region as well as hematopoietic cell function

CELLULAR PROCESS

cell organization/biogenesis

PHYSIOLOGICAL PROCESS

text	hematopoiesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS