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FLASH GENE
Symbol TSPAN32 contributors: npt - updated : 18-11-2003
HGNC name tetraspanin 32
HGNC id 13410
DNA
TYPE functioning gene
STRUCTURE 16.00 kb     10 Exon(s)
text structure 1 to 8a and 8b
MAPPING cloned Y linked N status provisional
Map pter - NAP1L4 - PHLDA2 - SLC22A18 - CDKN1C - KCNQ1 - TSSC4 - CD81 - TSPAN32 - ASCL2 - TH - INS - IGF2 - H19 - cen
Authors Nicholson (00)
RNA
TRANSCRIPTS type messenger
text four different spliced transcripts form 1.5 to 4.4 kb
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1327 - 320 - Robb
- - 1256 - 290 - Robb
- - 1207 - 124 - Robb
- - 1271 - 258 - Robb
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Lymphoid/ImmuneB cell
cell lineage hematopoietic cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four hydrophobic regions
  • an N terminal cytoplasmic domain
  • a transmembrane domain
  • a several potential phosphorylations sites
  • HOMOLOGY
    interspecies ortholog to murine Phemx
    intraspecies homolog to CD81
    Homologene
    FAMILY
  • tetraspanin (TM4SF) family
  • CATEGORY tumor suppressor , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be playing a role in malignancies and disease that involve this region as well as hematopoietic cell function
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text hematopoiesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS