Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
| loss of function
|
by hypermethylation in ovarian carcinoma |
tumoral
|  
| amplification
|  
|  
|
with MET oncogene in gastric cancer |
constitutional
|  
|  
| --low
|  
|
association between reduced TES expression and coronary artery disease ![](pubmed.jpg) |
tumoral
|  
| LOH
|  
|  
|
in primary gastric cancer ![](pubmed.jpg) |
tumoral
|  
|  
| --low
|  
|
is the most frequently methylated and silenced gene yet reported in childhood acute lymphoblastic leukaemia ![](pubmed.jpg) |
constitutional
|  
|  
| --low
|  
|
associate with loss by cells epithelial morphology and gain migratory and invasive properties of mesenchymal cells ![](pubmed.jpg) |
tumoral
|  
|  
|  
| loss of function
|
in human endometrial carcinoma ![](pubmed.jpg) |
tumoral
|  
|  
| --other
|  
|
is aberrantly methylated in ALL ![](pubmed.jpg) |