basic FUNCTION
| mobilizing intracellular calcium in response to urotensin 2 for arterial constriction |
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playing a possible role in the pathophysiology of atherosclerosis |
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its activation leads to an increase in Ca(2+), activation of phospholipase A(2) (PLA(2)) and an increase in arachidonic acid |
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intrahepatic UTS2/UTS2R system has an important pathophysiological role in cirrhosis and portal hypertension |
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appears to be involved in the regulation of colon cancer cell invasion and motility |
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is likely involved in the regulation of motility, invasion and proliferation of bladder cancer cells |