1 | VHL, ZNF350
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| ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer.
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| Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, Chen S, Hao J, Wang J, Huang Q, Xu H, Ye Z.
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| Oncotarget 6(9):6959-76.
2015
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2 | ZNF350
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| Tetrameric ZBRK1 DNA binding domain has affinity towards cognate DNA in absence of zinc ions.
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| Yadav LR, Biswal MN, Vikrant, Hosur MV, Varma AK.
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| Biochem Biophys Res Commun 450(1):283-8. doi: 10.1016/j.bbrc.2014.05.104. Epub 2014 Jun 9.
2014
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3 | FGF2, GADD45A, LCOR, TRIM28, ZNF350
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| Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1.
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| Calderon MR, Verway M, Benslama RO, Birlea M, Bouttier M, Dimitrov V, Mader S, White JH.
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| Nucleic Acids Res 42(11):7012-27. doi: 10.1093/nar/gku413. Epub 2014 May 14.
2014
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4 | ZNF350
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| Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer.
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| Lin LF, Li CF, Wang WJ, Yang WM, Wang DD, Chang WC, Lee WH, Wang JM.
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| PLoS One 8(8):e73033. doi: 10.1371/journal.pone.0073033. eCollection 2013.
2013
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5 | ZNF350
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| ZBRK1 represses HIV-1 LTR-mediated transcription.
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| Nishitsuji H, Abe M, Sawada R, Takaku H.
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| FEBS Lett 586(20):3562-8. doi: 10.1016/j.febslet.2012.08.010. Epub 2012 Aug 17.
2012
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6 | ATXN2, ZNF350
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| The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
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| Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S.
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| Hum Mol Genet 20(1):104-14. Epub 2010 Oct 6.
2011
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7 | ZNF350
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| ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer.
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| Lin LF, Chuang CH, Li CF, Liao CC, Cheng CP, Cheng TL, Shen MR, Tseng JT, Chang WC, Lee WH, Wang JM.
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| Cancer Res 70(1):192-201. Epub 2009 Dec 8.PMID: 19996286 2010
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8 | CTBP1, E2F1, RB1, RBBP8, TRIM28, ZNF350
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| RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
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| Liao CC, Tsai CY, Chang WC, Lee WH, Wang JM.
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| J Biol Chem 285(43):33134-43. Epub 2010 Aug 16.
2010
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9 | MID1, ZNF10, ZNF350, ZNF689
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| KAP1-independent transcriptional repression of SCAN-KRAB-containing zinc finger proteins.
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| Itokawa Y, Yanagawa T, Yamakawa H, Watanabe N, Koga H, Nagase T.
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| Biochem Biophys Res Commun 388(4):689-94. Epub 2009 Aug 18.PMID: 19695231 2009
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10 | ZNF350
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| Polymorphisms in BRCA1, BRCA1-interacting genes and susceptibility of breast cancer in Chinese women.
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| Huo X, Lu C, Huang X, Hu Z, Jin G, Ma H, Wang X, Qin J, Wang X, Shen H, Tang J.
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| J Cancer Res Clin Oncol 135(11):1569-75. Epub 2009 May 31.PMID: 19484476 2009
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11 | ZNF350
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| Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families.
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| Desjardins S, Belleau P, Labrie Y, Ouellette G, Bessette P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M; INHERIT BRCAs, Durocher F.
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| Int J Cancer 122(1):108-16.PMID: 17764113 2008
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12 | BRCA1, RBBP8, ZNF350
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| Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.
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| Furuta S, Wang JM, Wei S, Jeng YM, Jiang X, Gu B, Chen PL, Lee EY, Lee WH.
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| Cancer Cell 10(1):13-24.
2006
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13 | ZNF350, ZNF589
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| A common DNA-binding site for SZF1 and the BRCA1-associated zinc finger protein, ZBRK1.
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| Peng H, Zheng L, Lee WH, Rux JJ, Rauscher FJ 3rd.
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| Cancer Res 62(13):3773-81. 2002
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14 | ZNF350
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| Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells.
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| Ran Q, Wadhwa R, Bischof O, Venable S, Smith JR, Pereira-Smith OM.
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| Exp Cell Res 263(1):156-62. 2001
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15 | BRCA1, ZNF350
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| Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1.
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| Zheng L, Pan H, Li S, Flesken-Nikitin A, Chen PL, Boyer TG, Lee WH.
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| Mol Cell 6(4):757-68. 2000
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