Citations for
1VHL, ZNF350
ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer.
Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, Chen S, Hao J, Wang J, Huang Q, Xu H, Ye Z.
Oncotarget 6(9):6959-76. 2015
2ZNF350
Tetrameric ZBRK1 DNA binding domain has affinity towards cognate DNA in absence of zinc ions.
Yadav LR, Biswal MN, Vikrant, Hosur MV, Varma AK.
Biochem Biophys Res Commun 450(1):283-8. doi: 10.1016/j.bbrc.2014.05.104. Epub 2014 Jun 9. 2014
3FGF2, GADD45A, LCOR, TRIM28, ZNF350
Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1.
Calderon MR, Verway M, Benslama RO, Birlea M, Bouttier M, Dimitrov V, Mader S, White JH.
Nucleic Acids Res 42(11):7012-27. doi: 10.1093/nar/gku413. Epub 2014 May 14. 2014
4ZNF350
Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer.
Lin LF, Li CF, Wang WJ, Yang WM, Wang DD, Chang WC, Lee WH, Wang JM.
PLoS One 8(8):e73033. doi: 10.1371/journal.pone.0073033. eCollection 2013. 2013
5ZNF350
ZBRK1 represses HIV-1 LTR-mediated transcription.
Nishitsuji H, Abe M, Sawada R, Takaku H.
FEBS Lett 586(20):3562-8. doi: 10.1016/j.febslet.2012.08.010. Epub 2012 Aug 17. 2012
6ATXN2, ZNF350
The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S.
Hum Mol Genet 20(1):104-14. Epub 2010 Oct 6. 2011
7ZNF350
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer.
Lin LF, Chuang CH, Li CF, Liao CC, Cheng CP, Cheng TL, Shen MR, Tseng JT, Chang WC, Lee WH, Wang JM.
Cancer Res 70(1):192-201. Epub 2009 Dec 8.PMID: 19996286 2010
8CTBP1, E2F1, RB1, RBBP8, TRIM28, ZNF350
RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
Liao CC, Tsai CY, Chang WC, Lee WH, Wang JM.
J Biol Chem 285(43):33134-43. Epub 2010 Aug 16. 2010
9MID1, ZNF10, ZNF350, ZNF689
KAP1-independent transcriptional repression of SCAN-KRAB-containing zinc finger proteins.
Itokawa Y, Yanagawa T, Yamakawa H, Watanabe N, Koga H, Nagase T.
Biochem Biophys Res Commun 388(4):689-94. Epub 2009 Aug 18.PMID: 19695231 2009
10ZNF350
Polymorphisms in BRCA1, BRCA1-interacting genes and susceptibility of breast cancer in Chinese women.
Huo X, Lu C, Huang X, Hu Z, Jin G, Ma H, Wang X, Qin J, Wang X, Shen H, Tang J.
J Cancer Res Clin Oncol 135(11):1569-75. Epub 2009 May 31.PMID: 19484476 2009
11ZNF350
Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families.
Desjardins S, Belleau P, Labrie Y, Ouellette G, Bessette P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M; INHERIT BRCAs, Durocher F.
Int J Cancer 122(1):108-16.PMID: 17764113 2008
12BRCA1, RBBP8, ZNF350
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.
Furuta S, Wang JM, Wei S, Jeng YM, Jiang X, Gu B, Chen PL, Lee EY, Lee WH.
Cancer Cell 10(1):13-24. 2006
13ZNF350, ZNF589
A common DNA-binding site for SZF1 and the BRCA1-associated zinc finger protein, ZBRK1.
Peng H, Zheng L, Lee WH, Rux JJ, Rauscher FJ 3rd.
Cancer Res 62(13):3773-81. 2002
14ZNF350
Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells.
Ran Q, Wadhwa R, Bischof O, Venable S, Smith JR, Pereira-Smith OM.
Exp Cell Res 263(1):156-62. 2001
15BRCA1, ZNF350
Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1.
Zheng L, Pan H, Li S, Flesken-Nikitin A, Chen PL, Boyer TG, Lee WH.
Mol Cell 6(4):757-68. 2000