| 1 | HTX1, ZIC3
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| The phenotypic spectrum of ZIC3 mutations includes isolated d-transposition of the great arteries and double outlet right ventricle.
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| D'Alessandro LC, Latney BC, Paluru PC, Goldmuntz E.
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| Am J Med Genet A m J Med Genet A. 2013 Feb 20. doi: 10.1002/ajmg.a.35849. [Epub ahead of print]
2013
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| 2 | ZIC3
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| Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning.
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| Sutherland MJ, Wang S, Quinn ME, Haaning A, Ware SM.
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| Hum Mol Genet um Mol Genet. 2013 Jan 8. [Epub ahead of print]
2013
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| 3 | ZIC3
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| Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development.
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| Jiang Z, Zhu L, Hu L, Slesnick TC, Pautler RG, Justice MJ, Belmont JW.
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| Hum Mol Genet 22(5):879-89. doi: 10.1093/hmg/dds494. Epub 2012 Nov 25.
2013
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| 4 | ZIC3
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| Zic3 induces conversion of human fibroblasts to stable neural progenitor-like cells.
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| Kumar A, Declercq J, Eggermont K, Agirre X, Prosper F, Verfaillie CM.
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| J Mol Cell Biol 4(4):252-5. doi: 10.1093/jmcb/mjs015. Epub 2012 Apr 15. No abstract available.
2012
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| 5 | HTX1, ZIC3
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| Situs Inversus Totalis and a Novel ZIC3 Mutation in a Family with X-linked Heterotaxy.
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| D'Alessandro LC, Casey B, Siu VM.
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| Congenit Heart Dis ongenit Heart Dis. 2011 Dec 16. doi: 10.1111/j.1747-0803.2011.00602.x. [Epub ahead of print]
2011
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| 6 | HTX1, ZIC3
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| Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease.
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| Bedard JE, Haaning AM, Ware SM.
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| PLoS One 6(8):e23755. doi: 10.1371/journal.pone.0023755. Epub 2011 Aug 17.
2011
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| 7 | VACTERLX, ZIC3
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| From VACTERL-H to heterotaxy: variable expressivity of ZIC3-related disorders.
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| Chung B, Shaffer LG, Keating S, Johnson J, Casey B, Chitayat D.
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| Am J Med Genet A 155A(5):1123-8. doi: 10.1002/ajmg.a.33859. Epub 2011 Apr 4.
2011
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| 8 | NANOG, ZIC3
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| The pluripotency regulator Zic3 is a direct activator of the Nanog promoter in ESCs.
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| Lim LS, Hong FH, Kunarso G, Stanton LW.
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| Stem Cells 28(11):1961-9. doi: 10.1002/stem.527.
2010
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| 9 | GLI3, ZIC3
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| Characterization of the interactions of human ZIC3 mutants with GLI3.
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| Zhu L, Zhou G, Poole S, Belmont JW.
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| Hum Mutat 29(1):99-105. 2008
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| 10 | ZIC3, HTX1
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| Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3.
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| Bedard JE, Purnell JD, Ware SM.
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| Hum Mol Genet 16(2):187-98. Epub 2006 Dec 21. 2007
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| 11 | NPPA,SRF,ZIC3
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| Identification of a novel role of ZIC3 in regulating cardiac development.
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| Zhu L, Harutyunyan KG, Peng JL, Wang J, Schwartz RJ, Belmont JW.
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| Hum Mol Genet 16(14):1649-60. Epub 2007 Apr 27. 2007
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| 12 | NANOG, POU5F1, SOX2, ZIC3
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| Zic3 is required for maintenance of pluripotency in embryonic stem cells.
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| Lim LS, Loh YH, Zhang W, Li Y, Chen X, Wang Y, Bakre M, Ng HH, Stanton LW.
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| Mol Biol Cell 18(4):1348-58. Epub 2007 Jan 31.
2007
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| 13 | DWS1, ZIC1, ZIC2, ZIC3, ZIC4
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| The ZIC gene family in development and disease.
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| Grinberg I, Millen KJ.
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| Clin Genet 67(4):290-6. 2005
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| 14 | HTX1, ZIC3
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| Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects.
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| Ware SM, Peng J, Zhu L, Fernbach S, Colicos S, Casey B, Towbin J, Belmont JW.
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| Am J Hum Genet 74(1):93-105. Epub 2003 Dec 16. 2004
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| 15 | ZIC1, ZIC2, ZIC3, ZIC4, ZIC5
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| Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
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| Ishiguro A, Inoue T, Mikoshiba K, Aruga J.
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| Biochem Biophys Res Commun 324(1):302-7. 2004
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| 16 | HTX1, ZIC3
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| X-linked transposition of the great arteries and incomplete penetrance among males with a nonsense mutation in ZIC3.
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| Megarbane A, Salem N, Stephan E, Ashoush R, Lenoir D, Delague V, Kassab R, Loiselet J, Bouvagnet P.
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| Eur J Hum Genet 8(9):704-8. 2000
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| 17 | HTX1, ZIC3
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| A deletion encompassing Zic3 in bent tail, a mouse model for X-linked neural tube defects.
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| Klootwijk R, Franke B, van der Zee CE, de Boer RT, Wilms W, Hol FA, Mariman EC.
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| Hum Mol Genet 9(11):1615-22. 2000
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| 18 | HTX1, ZIC1, ZIC3
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| X-linked situs abnormalities result from mutations in ZIC3.
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| Gebbia M, Ferrero GB, Pilia G, Bassi MT, Aylsworth A, Penman-Splitt M, Bird LM, Bamforth JS, Burn J, Schlessinger D, Nelson DL, Casey B.
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| Nat Genet 17(3):305-8. 1997
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