1 | MRXS37, ZFX
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| Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt.
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| Shepherdson JL, Hutchison K, Don DW, McGillivray G, Choi TI, Allan CA, Amor DJ, Banka S, Basel DG, Buch LD, Carere DA, Carroll R, Clayton-Smith J, Crawford A, Dunø M, Faivre L, Gilfillan CP, Gold NB, Gripp KW, Hobson E, Holtz AM, Innes AM, Isidor B, Jackson A, Katsonis P, Amel Riazat Kesh L; Genomics England Research Consortium; Küry S, Lecoquierre F, Lockhart P, Maraval J, Matsumoto N, McCarrier J, McCarthy J, Miyake N, Moey LH, Németh AH, Østergaard E, Patel R, Pope K, Posey JE, Schnur RE, Shaw M, Stolerman E, Taylor JP, Wadman E, Wakeling E, White SM, Wong LC, Lupski JR, Lichtarge O, Corbett MA, Gecz J, Nicolet CM, Farnham PJ, Kim CH, Shinawi M.
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| Am J Hum Genet. Am J Hum Genet. 2024
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2 | ZFX
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| Reduction of ZFX levels decreases histone H4 acetylation and increases Pol2 pausing at target promoters.
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| Hsu E, Hutchison K, Liu Y, Nicolet CM, Schreiner S, Zemke NR, Farnham PJ.
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| Nucleic Acids Res. May 10:gkae372. doi: 10.1093/nar/gkae372. Epub ahead of print. 2024
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3 | ZFX
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| ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream of transcription start sites at the majority of CpG island promoters.
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| Rhie SK, Yao L, Luo Z, Witt H, Schreiner S, Guo Y, Perez AA, Farnham PJ.
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| Genome Res. Feb 2;28(3):310–20. doi: 10.1101/gr.228809.117. Epub ahead of print. 2018
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4 | ZFX
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| The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation.
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| Smith-Raska MR, Arenzana TL, D'Cruz LM, Khodadadi-Jamayran A, Tsirigos A, Goldrath AW, Reizis B.
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| Front Immunol Jul 4;9:1482. doi: 10.3389/fimmu.2018.01482. 2018
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5 | SET, ZFX
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| Zinc Finger and X-Linked Factor (ZFX) Binds to Human SET Transcript 2 Promoter and Transactivates SET Expression.
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| Xu S, Duan P, Li J, Senkowski T, Guo F, Chen H, Romero A, Cui Y, Liu J, Jiang SW.
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| Int J Mol Sci. Oct 20;17(10):1737. doi: 10.3390/ijms17101737. 2016
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6 | ZFX
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| ZFX is a Strong Predictor of Poor Prognosis in Renal Cell Carcinoma
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| Li C, Li H, Zhang T, Li J, Ma F, Li M, Sui Z, Chang J.
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| Med Sci Monit. Nov 5;21:3380-5. doi: 10.12659/msm.894708. 2015
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7 | ZFX
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| Recurrent ZFX mutations in human sporadic parathyroid adenomas.
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| Soong CP, Arnold A.
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| Oncoscience. May 6;1(5):360-6. doi: 10.18632/oncoscience.116. Erratum in: Oncoscience. 2015;2(1):1-2. 2014
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8 | ZFX
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| ZFX regulates glioma cell proliferation and survival in vitro and in vivo.
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| Zhu Z, Li K, Xu D, Liu Y, Tang H, Xie Q, Xie L, Liu J, Wang H, Gong Y, Hu Z, Zheng J.
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| J Neurooncol. Mar;112(1):17-25. doi: 10.1007/s11060-012-1032-z. Epub 2013 Jan 16. Erratum in: J Neurooncol. 2013 Jul;113(3):533. 2013
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9 | ZFX
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| ZFX controls the self-renewal of human embryonic stem cells.
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| Harel S, Tu EY, Weisberg S, Esquilin M, Chambers SM, Liu B, Carson CT, Studer L, Reizis B, Tomishima MJ.
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| PLoS One. 7(8):e42302. doi: 10.1371/journal.pone.0042302. Epub 2012 Aug 3 2012
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10 | ZFX
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| Knockdown of zinc finger protein, X-linked (ZFX) inhibits cell proliferation and induces apoptosis in human laryngeal squamous cell carcinoma.
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| Fang J, Yu Z, Lian M, Ma H, Tai J, Zhang L, Han D.
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| Mol Cell Biochem ol Cell Biochem. 2011 Oct 19. [Epub ahead of print]
2011
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11 | ZFX
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| Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.
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| Arenzana TL, Smith-Raska MR, Reizis B.
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| Blood 113(23):5857-67. Epub 2009 Mar 27.
2009
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12 | ZFX
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| Zfx controls the self-renewal of embryonic and hematopoietic stem cells.
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| Galan-Caridad JM, Harel S, Arenzana TL, Hou ZE, Doetsch FK, Mirny LA, Reizis B.
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| Cell 129(2):345-57.
2007
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13 | ZFX
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| CpG islands in human ZFX and ZFY and mouse Zfx genes: sequence similarities and methylation differences.
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| Luoh SW, Jegalian K, Lee A, Chen EY, Ridley A, Page DC.
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| Genomics 29(2):353-63. 1995
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14 | POLA1, ZFX
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| Identification of YAC and cosmid clones encompassing the ZFX-POLA region using irradiation hybrid cell lines.
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| Francis F, et al.
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| Genomics 20 : 75-83. 1994
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15 | ZFX, ZFY
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| Chromosomal localisation of a gene(s) for Turner stigmata on Yp.
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| Ogata T, et al.
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| J Med Genet 30 : 918-922. 1993
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16 | ZFX
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| A common EcoRI polymorphism at the ZFX locus.
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| Ellison J, et al.
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| Hum Mol Genet 1 : 782. 1992
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17 | ZFX
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| Chromosomal localization of ZFX : a human gene that escapes X inactivation and its murine homologs.
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| Page DC, et al.
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| Genomics 7 : 37-46. 1990
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18 | ZFX
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| pDP1007, detects an X polymorphism with HindIII in negroids at the ZFX locus.
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| Spurdle AB, et al.
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| Nucleic Acids Res 18 : 3430. 1990
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19 | ZFX, ZFY
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| Regional assignments of the zinc-finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.
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| Leung WY, et al.
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| Cytogenet Cell Genet 54 : 151-153. 1990
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20 | ZFX
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| Duplication of an Xp segment that includes the ZFX locus causes sex inversion in man.
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| Scherer G, et al.
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| Hum Genet 81 : 291-294. 1989
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21 | ZFX
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| Mapping the human ZFX locus to Xp21.3 by in situ hybridization.
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| MŸller G, et al.
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| Hum Genet 82 : 82-84. 1989
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22 | ZFX
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| ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.
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| Schneider-GŠdicke A, et al.
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| Cell 57 : 1247-1258. 1989
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23 | ZFX
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| Putative transcription activator with alternative isoforms encoded by human ZFX gene.
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| Schneider-Gadicke A, Beer-Romero P, Brown LG, Mardon G, Luoh SW, Page DC.
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| Nature 342 : 708-711. 1989
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24 | SRY, ZFX, ZFY, DXYS42X, DXYS42Y
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| The sex-determining region of the human Y chromosome encodes a finger protein.
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| Page DC, Mosher R, Simpson EM, Fisher EM, Mardon G, Pollack J, McGillivray B, de la Chapelle A, Brown LG.
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| Cell 51 : 1091-1104. 1987
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