| 1 | XAF1, YY1
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| YY1 negatively regulates the XAF1 gene expression in prostate cancer.
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| Camacho-Moctezuma B, Quevedo-Castillo M, Melendez-Zajgla J, Aquino-Jarquin G, Martinez-Ruiz GU.
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| Biochem Biophys Res Commun 508(3):973-979. doi: 10.1016/j.bbrc.2018.12.056. Epub 2018 Dec 11.
2019
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| 2 | MRFFE, YY1
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| YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction.
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| Gabriele M, Vulto-van Silfhout AT, Germain PL, Vitriolo A, Kumar R, Douglas E, Haan E, Kosaki K, Takenouchi T, Rauch A, Steindl K, Frengen E, Misceo D, Pedurupillay CRJ, Stromme P, Rosenfeld JA, Shao Y, Craigen WJ, Schaaf CP, Rodriguez-Buritica D, Farach L, Friedman J, Thulin P, McLean SD, Nugent KM, Morton J, Nicholl J, Andrieux J, Stray-Pedersen A, Chambon P, Patrier S, Lynch SA, Kjaergaard S, Tørring PM, Brasch-Andersen C, Ronan A, van Haeringen A, Anderson PJ, Powis Z, Brunner HG, Pfundt R, Schuurs-Hoeijmakers JHM, van Bon BWM, Lelieveld S, Gilissen C, Nillesen WM, Vissers LELM, Gecz J, Koolen DA, Testa G, de Vries BBA.
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| Am J Hum Genet 100(6):907-925. doi: 10.1016/j.ajhg.2017.05.006.
2017
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| 3 | NFKB1, TGFA, YY1
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| Transcriptional Regulation of Human Transforming Growth Factor-α in Astrocytes
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| Karki P, Johnson J Jr, Son DS, Aschner M, Lee E.
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| Mol Neurobiol. Mar;54(2):964-976. doi: 10.1007/s12035-016-9705-9. Epub 2016 Jan 21. 2017
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| 4 | UBIAD1, YY1
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| YY1 positively regulates human UBIAD1 expression.
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| Funahashi N, Hirota Y, Nakagawa K, Sawada N, Watanabe M, Suhara Y, Okano T.
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| Biochem Biophys Res Commun 460(2):238-44. doi: 10.1016/j.bbrc.2015.03.018. Epub 2015 Mar 12.
2015
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| 5 | BTG2, HAMP, YY1
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| B-cell translocation gene 2 promotes hepatic hepcidin production via induction of Yin Yang 1.
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| Lee SE, Hwang SL, Jang WG, Chang HW, Kim YD.
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| Biochem Biophys Res Commun 460(4):996-1001. doi: 10.1016/j.bbrc.2015.03.140.
2015
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| 6 | NFYA, NFYB, NFYC, PCYT2, YY1
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| Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 1
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| Ando H, Aoyama C, Horibata Y, Satou M, Mitsuhashi S, Itoh M, Hosaka K, Sugimoto H.
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| Biochem J. Nov 1;471(3):369-79. doi: 10.1042/BJ20150318. Epub 2015 Aug 26. 2015
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| 7 | BIRC5, YY1
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| Yin Yang 1 regulates the transcriptional repression of Survivin.
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| Galloway NR, Diaz Osterman CJ, Reiber K, Jutzy JM, Li F, Sui G, Soto U, Wall NR.
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| Biochem Biophys Res Commun 445(1):208-13. doi: 10.1016/j.bbrc.2014.01.169. Epub 2014 Feb 4.
2014
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| 8 | EWSR1, YY1
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| RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12).
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| Panagopoulos I, Thorsen J, Gorunova L, Micci F, Haugom L, Davidson B, Heim S.
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| Genes Chromosomes Cancer 52(8):733-40. doi: 10.1002/gcc.22068. Epub 2013 Apr 30.
2013
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| 9 | GATA3, YY1
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| Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
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| Hwang SS, Kim YU, Lee S, Jang SW, Kim MK, Koh BH, Lee W, Kim J, Souabni A, Busslinger M, Lee GR.
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| Proc Natl Acad Sci U S A 110(1):276-81. doi: 10.1073/pnas.1214682110. Epub 2012 Dec 17.
2013
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| 10 | HCFC1, MRX3, YY1
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| A Noncoding, Regulatory Mutation Implicates HCFC1 in Nonsyndromic Intellectual Disability.
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| Huang L, Jolly LA, Willis-Owen S, Gardner A, Kumar R, Douglas E, Shoubridge C, Wieczorek D, Tzschach A, Cohen M, Hackett A, Field M, Froyen G, Hu H, Haas SA, Ropers HH, Kalscheuer VM, Corbett MA, Gecz J.
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| Am J Hum Genet 91(4):694-702. doi: 10.1016/j.ajhg.2012.08.011. Epub 2012 Sep 20.
2012
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| 11 | CCND1, CDK4, YY1
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| Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1.
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| Ishii H, Hulett MD, Li JM, Santiago FS, Parish CR, Khachigian LM.
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| Int J Oncol 40(5):1575-80. doi: 10.3892/ijo.2012.1362. Epub 2012 Feb 9.
2012
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| 12 | MITF, YY1
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| YY1 regulates melanocyte development and function by cooperating with MITF.
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| Li J, Song JS, Bell RJ, Tran TN, Haq R, Liu H, Love KT, Langer R, Anderson DG, Larue L, Fisher DE.
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| PLoS Genet 8(5):e1002688. doi: 10.1371/journal.pgen.1002688. Epub 2012 May 3.
2012
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| 13 | BRCA1, YY1
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| Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation.
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| Lee MH, Lahusen T, Wang RH, Xiao C, Xu X, Hwang YS, He WW, Shi Y, Deng CX.
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| Oncogene 31(1):116-27. doi: 10.1038/onc.2011.217. Epub 2011 Jun 13.
2012
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| 14 | MYO7A, YY1
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| A DNA variant within the MYO7A promoter regulates YY1 transcription factor binding and gene expression serving as a potential dominant DFNA11 auditory genetic modifier.
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| Street VA, Li J, Robbins CA, Kallman JC.
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| J Biol Chem 286(17):15278-86. Epub 2011 Mar 4.
2011
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| 15 | XIST, YY1
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| YY1 tethers Xist RNA to the inactive X nucleation center.
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| Jeon Y, Lee JT.
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| Cell 146(1):119-33.
2011
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| 16 | VIM, YY1
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| CpG methylation prevents YY1-mediated transcriptional activation of the vimentin promoter.
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| Sekimata M, Murakami-Sekimata A, Homma Y.
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| Biochem Biophys Res Commun 414(4):767-72. doi: 10.1016/j.bbrc.2011.09.155. Epub 2011 Oct 7.
2011
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| 17 | POSTN, YY1
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| Negative transcriptional regulation of the human periostin gene by YingYang-1 transcription factor.
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| Romeo F, Falbo L, Di Sanzo M, Misaggi R, Faniello MC, Barni T, Cuda G, Viglietto G, Santoro C, Quaresima B, Costanzo F.
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| Gene 487(2):129-34. doi: 10.1016/j.gene.2011.07.025. Epub 2011 Aug 3.
2011
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| 18 | FRG2, MECP2, SLC25A4, YY1
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| The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis.
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| Forlani G, Giarda E, Ala U, Di Cunto F, Salani M, Tupler R, Kilstrup-Nielsen C, Landsberger N.
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| Hum Mol Genet 19(16):3114-23. Epub 2010 May 26.PMID: 20504995 2010
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| 19 | BAP1, COX7C, HCFC1, YY1
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| The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.
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| Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky E, Milot E, Shi Y, Affar el B.
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| Mol Cell Biol 30(21):5071-85. Epub 2010 Aug 30. 2010
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| 20 | EGR2, YY1
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| Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination.
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| He Y, Kim JY, Dupree J, Tewari A, Melendez-Vasquez C, Svaren J, Casaccia P.
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| Nat Neurosci 13(12):1472-80. doi: 10.1038/nn.2686. Epub 2010 Nov 7.
2010
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| 21 | CNMD, YY1
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| Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells.
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| Aoyama T, Okamoto T, Fukiage K, Otsuka S, Furu M, Ito K, Jin Y, Ueda M, Nagayama S, Nakayama T, Nakamura T, Toguchida J.
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| J Biol Chem 285(39):29842-50. doi: 10.1074/jbc.M110.116319. Epub 2010 Jul 27.
2010
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| 22 | YY1
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| Transcription factor Yin Yang 1 represses fetal troponin I gene expression in neonatal myocardial cells.
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| Nan C, Huang X.
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| Biochem Biophys Res Commun 378(1):62-7. Epub 2008 Nov 12.
2009
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| 23 | YY1
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| Yin Yang 1 regulates the transcriptional activity of androgen receptor.
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| Deng Z, Wan M, Cao P, Rao A, Cramer SD, Sui G.
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| Oncogene 28(42):3746-57. Epub 2009 Aug 10.
2009
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| 24 | GDAP1, YY1
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| YY1-dependent transcriptional regulation of the human GDAP1 gene.
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| Ratajewski M, Pulaski L.
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| Genomics 94(6):407-13. Epub 2009 Aug 29.PMID: 19720140 2009
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| 25 | CBX5, YY1
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| The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells.
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| Lieberthal JG, Kaminsky M, Parkhurst CN, Tanese N.
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| Breast Cancer Res 11(3):R42. Epub 2009 Jun 30.PMID: 19566924 2009
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| 26 | YY1
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| Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1.
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| Wu S, Murai S, Kataoka K, Miyagishi M.
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| Biochem Biophys Res Commun 365(1):75-81. Epub 2007 Nov 1. 2008
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| 27 | MMP9, YY1
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| Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons.
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| Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L.
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| J Biol Chem 283(50):35140-53. Epub 2008 Oct 21.
2008
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| 28 | CEBPD, SUZ12, YY1
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| Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex.
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| Ko CY, Hsu HC, Shen MR, Chang WC, Wang JM.
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| J Biol Chem 283(45):30919-32. Epub 2008 Aug 27.PMID: 18753137 2008
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| 29 | PRDM2, YY1
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| Silencing of YY1 downregulates RIZ1 promoter in human osteosarcoma.
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| Abbondanza C, de Nigris F, De Rosa C, Rossiello R, Puca GA, Napoli C.
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| Oncol Res 17(1):33-41.PMID: 18488713 2008
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| 30 | REST, YY1
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| Yin yang 1 directly regulates the transcription of RE-1 silencing transcription factor.
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| Jiang L, Yao M, Shi J, Shen P, Niu G, Fei J.
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| J Neurosci Res 86(6):1209-16.PMID: 18092359 2008
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| 31 | YY1, PHB, E2F1, TP53, CASP7
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| Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.
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| Joshi B, Rastogi S, Morris M, Carastro LM, DeCook C, Seto E, Chellappan SP.
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| Biochem J 401(1):155-66. 2007
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| 32 | YY1
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| YY1 as a controlling factor for the Peg3 and Gnas imprinted domains.
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| Do Kim J, Hinz AK, Ha Choo J, Stubbs L, Kim J.
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| Genomics 89(2):262-9. Epub 2006 Oct 25. 2007
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| 33 | YY1
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| Yin Yang 1 is a critical regulator of B-cell development.
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| Liu H, Schmidt-Supprian M, Shi Y, Hobeika E, Barteneva N, Jumaa H, Pelanda R, Reth M, Skok J, Rajewsky K, Shi Y.
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| Genes Dev 21(10):1179-89.
2007
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| 34 | YY1
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| Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.
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| Santiago FS, Ishii H, Shafi S, Khurana R, Kanellakis P, Bhindi R, Ramirez MJ, Bobik A, Martin JF, Chesterman CN, Zachary IC, Khachigian LM.
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| Circ Res 101(2):146-55. Epub 2007 Jun 7.
2007
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| 35 | INO80, YY1
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| YY1 functions with INO80 to activate transcription.
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| Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW.
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| Nat Struct Mol Biol 14(9):872-4. Epub 2007 Aug 26.
2007
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| 36 | YY1, HOXA11
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| Yin Yang 1 physically interacts with Hoxa11 and represses Hoxa11-dependent transcription.
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| Luke MP, Sui G, Liu H, Shi Y.
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| J Biol Chem 281(44):33226-32. Epub 2006 Sep 7. 2006
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| 37 | YY1
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| A role for Yin Yang-1 (YY1) in the assembly of snRNA transcription complexes.
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| Emran F, Florens L, Ma B, Swanson SK, Washburn MP, Hernandez N.
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| Gene 377:96-108. Epub 2006 May 20. 2006
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| 38 | YY1
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| Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression.
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| Affar el B, Gay F, Shi Y, Liu H, Huarte M, Wu S, Collins T, Li E, Shi Y.
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| Mol Cell Biol 26(9):3565-81. 2006
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| 39 | YY1
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| Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy.
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| Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA.
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| Biochem Biophys Res Commun 326(1):79-86. 2005
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| 40 | YY1, REST
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| Identification and characterization of four novel peptide motifs that recognize distinct regions of the transcription factor CP2.
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| Kang HC, Chung BM, Chae JH, Yang SI, Kim CG, Kim CG.
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| FEBS J 272(5):1265-77. 2005
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| 41 | FAS,YY1
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| Inhibition of the transcription factor Yin Yang 1 activity by S-nitrosation.
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| Hongo F, Garban H, Huerta-Yepez S, Vega M, Jazirehi AR, Mizutani Y, Miki T, Bonavida B.
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| Biochem Biophys Res Commun 336(2):692-701. 2005
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| 42 | YY1, YY2
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| Molecular cloning and functional characterization of the transcription factor YY2.
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| Nguyen N, Zhang X, Olashaw N, Seto E.
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| J Biol Chem 279(24):25927-34. Epub 2004 Apr 15. 2004
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| 43 | YY1, YY1AP1
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| YY1AP, a novel co-activator of YY1.
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| Wang CY, Liang YJ, Lin YS, Shih HM, Jou YS, Yu WC.
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| J Biol Chem 279(17):17750-5.
2004
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| 44 | CXCR4, YY1
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| Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin.
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| Cristillo AD, Bierer BE.
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| Mol Immunol 40(8):539-53. 2003
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| 45 | FRG1, HMGB2, NCL, SLC25A4 , YY1
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| Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle.
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| Gabellini D, Green MR, Tupler R.
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| Cell 110(3):339-48. 2002
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| 46 | YY1
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| Transcription factor Yin Yang 1 stimulates poly(ADP-ribosyl)ation and DNA repair.
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| Oei SL, Shi Y.
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| Biochem Biophys Res Commun 284(2):450-4. 2001
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| 47 | ATF6, NFYA, NFYB, NFYC, YY1
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| ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1.
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| Li M, Baumeister P, Roy B, Phan T, Foti D, Luo S, Lee AS.
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| Mol Cell Biol 20(14):5096-106. 2000
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| 48 | YY1
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| Cloning, chromosomal localization and promoter analysis of the human transcription factor YY1.
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| Yao YL, Dupont BR, Ghosh S, Fang Y, Leach RJ, Seto E.
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| Nucleic Acids Res 26 : 3776-3783. 1998
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| 49 | HDAC2, HDAC3, YY1
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| Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3.
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| Yang WM, et al.
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| Proc Natl Acad Sci U S A 93 : 12845-12850. 1996
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| 50 | YY1
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| Chromosomal localization of the transcription factor YY1 in the mouse and human.
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| Zhu W, et al.
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| Mamm Genome 5 : 234-236. 1994
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| 51 | YY1
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| Transcriptional repression by YY1, a human GLI-Krppel-related protein, and relief of repression by adenovirus E1A protein.
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| Shi Y, et al.
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| Cell 67 : 377-388. 1991
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| 52 | YY1
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| Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.
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| Park K, et al.
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| Proc Natl Acad Sci U S A 88 : 9804-9808. 1991
|