| 1 | IFIH1, YWHAH
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| The 14-3-3η chaperone protein promotes antiviral innate immunity via facilitating MDA5 oligomerization and intracellular redistribution
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| Lin JP, Fan YK, Liu HM.
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| PLoS Pathog. Feb 11;15(2):e1007582. doi: 10.1371/journal.ppat.1007582. 2019
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| 2 | YWHAH
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| Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14-3-3η in oncocytomas
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| Feng J, Zhang Q, Li C, Zhou Y, Zhao S, Hong L, Song Q, Yu S, Hu C, Wang H, Mao C, Shepard MJ, Hao S, Dominah G, Sun M, Wan H, Park DM, Gilbert MR, Xu G, Zhuang Z, Zhang Y
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| J Pathol. Jul;245(3):361-372. doi: 10.1002/path.5090. Epub 2018 May 29. 2018
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| 3 | YWHAH
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| Loss of function of Ywhah in mice induces deafness and cochlear outer hair cells' degeneration
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| Buret L, Rebillard G, Brun E, Angebault C, Pequignot M, Lenoir M, Do-Cruzeiro M, Tournier E, Cornille K, Saleur A, Gueguen N, Reynier P, Amati-Bonneau P, Barakat A, Blanchet C, Chinnery P, Yu-Wai-Man P, Kaplan J, Roux AF, Van Camp G, Wissinger B, Boespflug-Tanguy O, Giraudet F, Puel JL, Lenaers G, Hamel C, Delprat B, Delettre C.
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| Cell Death Discov. Mar 7;2:16017. doi: 10.1038/cddiscovery.2016.17. 2016
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| 4 | YWHAH, YWHAQ
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| Changes in Brain 14-3-3 Proteins in Response to Insulin Resistance Induced by a High Palatable Diet
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| Bock H, Zimmer AR, Zimmer ER, de Souza DO, Portela LV, Saraiva-Pereira ML.
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| Mol Neurobiol. Aug;52(1):710-8. doi: 10.1007/s12035-014-8905-4. Epub 2014 Oct 4. 2015
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| 5 | YWHAH
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| 14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage
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| Maksymowych WP, van der Heijde D, Allaart CF, Landewé R, Boire G, Tak PP, Gui Y, Ghahary A, Kilani R, Marotta A
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| Arthritis Res Ther. Apr 21;16(2):R99. doi: 10.1186/ar4547. 2014
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| 6 | YWHAH
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| Roles of 14-3-3η in mitotic progression and its potential use as a therapeutic target for cancers 2013
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| Lee CG, Park GY, Han YK, Lee JH, Chun SH, Park HY, Lim KH, Kim EG, Choi YJ, Yang K, Lee CW.
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| Oncogene Mar 21;32(12):1560-9. doi: 10.1038/onc.2012.170. Epub 2012 May 7 2013
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| 7 | YWHAH
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| Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation
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| De S, Kline D.
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| BMC Dev Biol. Apr 1;13:10. doi: 10.1186/1471-213X-13-10. Erratum in: BMC Dev Biol. 2014;14:20. 2013
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| 8 | YWHAH
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| 14-3-3 η inhibits chondrogenic differentiation of ATDC5 cell.
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| Yoon HE, Kim KS, Kim IY.
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| Biochem Biophys Res Commun 406(1):59-63. Epub 2011 Feb 1.
2011
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| 9 | HDAC7, YWHAE, YWHAH, YWHAZ
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| Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.
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| Margariti A, Zampetaki A, Xiao Q, Zhou B, Karamariti E, Martin D, Yin X, Mayr M, Li H, Zhang Z, De Falco E, Hu Y, Cockerill G, Xu Q, Zeng L.
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| Circ Res 106(7):1202-11. Epub 2010 Mar 11.
2010
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| 10 | YWHAH
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| Family-based association of YWHAH in psychotic bipolar disorder.
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| Grover D, Verma R, Goes FS, Mahon PL, Gershon ES, McMahon FJ, Potash JB; NIMH Genetics Initiative Bipolar Disorder Collaborative, Bipolar Disorder Phenome Group, Gershon ES, McMahon FJ, Potash JB.
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| Am J Med Genet B Neuropsychiatr Genet 150B(7):977-83.
2009
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| 11 | CAMK1, YWHAH
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| 14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.
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| Ichimura T, Taoka M, Hozumi Y, Goto K, Tokumitsu H.
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| FEBS Lett 582(5):661-5. Epub 2008 Jan 31.
2008
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| 12 | YWHAH
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| Detection of high levels of 2 specific isoforms of 14-3-3 proteins in synovial fluid from patients with joint inflammation.
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| Kilani RT, Maksymowych WP, Aitken A, Boire G, St-Pierre Y, Li Y, Ghahary A.
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| J Rheumatol 34(8):1650-7. Epub 2007 Jul 1. 2007
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| 13 | YWHAH, SCN5A
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| 14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.
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| Allouis M, Le Bouffant F, Wilders R, PŽroz D, Schott JJ, Noireaud J, Le Marec H, MŽrot J, Escande D, Bar— I.
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| Circ Res 98(12):1538-46. Epub 2006 May 25. 2006
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| 14 | GREM1, YWHAH
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| The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein.
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| Namkoong H, Shin SM, Kim HK, Ha SA, Cho GW, Hur SY, Kim TE, Kim JW.
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| BMC Cancer 6:74.
2006
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| 15 | YWHAH
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| 14-3-3eta is a novel regulator of parkin ubiquitin ligase.
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| Sato S, Chiba T, Sakata E, Kato K, Mizuno Y, Hattori N, Tanaka K.
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| EMBO J 25(1):211-21. Epub 2005 Aug 11.
2006
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| 16 | YWHAH
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| Role of 14-3-3 eta as a positive regulator of the glucocorticoid receptor transcriptional activation.
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| Kim YS, Jang SW, Sung HJ, Lee HJ, Kim IS, Na DS, Ko J.
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| Endocrinology 146(7):3133-40. Epub 2005 Mar 24. 2005
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| 17 | YWHAH, ZBTB17
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| Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage.
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| Wanzel M, Kleine-Kohlbrecher D, Herold S, Hock A, Berns K, Park J, Hemmings B, Eilers M.
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| Nat Cell Biol 7(1):30-41. Epub 2004 Dec 5. 2005
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| 18 | C22orf24, DEPDC5, YWHAH
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| Complex chromosome 22 rearrangements in astrocytic tumors identified using microsatellite and chromosome 22 tile path array analysis.
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| Seng TJ, Ichimura K, Liu L, Tingby O, Pearson DM, Collins VP.
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| Genes Chromosomes Cancer 43(2):181-93.
2005
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| 19 | ATXN1, YWHAB, YWHAE, YWHAH, YWHAZ
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| Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
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| Chen HK, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, Fernandez MH, Aitken A, Skoulakis EM, Orr HT, Botas J, Zoghbi HY.
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| Cell 113(4):457-68. 2003
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| 20 | YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ, YWHAR, YWHAZ
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| 14-3-3 proteins block apoptosis and differentially regulate MAPK cascades.
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| Xing H, Zhang S, Weinheimer C, Kovacs A, Muslin AJ.
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| EMBO J 19(3):349-358 2000
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| 21 | SCZD4, YWHAH
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| 14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia.
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| Toyooka K, et al.
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| Am J Med Genet 88(2):164-7. 1999
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| 22 | YWHAB, YWHAE, YWHAH, YWHAZ
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| The structural basis for 14-3-3 : phosphopeptide binding specificity.
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| Yaffe MB, Rittinger K, Volinia S, Caron PR, Aitken A, Leffers H, Gamblin SJ, Smerdon SJ, Cantley LC.
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| Cell 91(7):961-71. 1997
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| 23 | YWHAB, YWHAH, YWHAZ
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| Assignment of the human genes encoding 14-3-3 eta (YWHAH) to 22q12, 14-3-3 zeta (YWHAZ) to 2p25.1-p25.2, and 14-3-3 beta (YWHAB) to 20q13.1 by in situ hybridization.
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| Tommerup N, et al.
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| Genomics 33 : 149-150. 1996
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| 24 | YWHAH
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| Structural organization and chromosomal assignment of the human 14-3-3 eta chain gene (YNHAH).
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| Muratake T, et al.
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| Genomics 36 : 63-69. 1996
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| 25 | YWHAH
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| cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain.
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| Ischimura-Ohshima Y, et al.
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| J Neurosci Res 31 : 600-605. 1992
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| 26 | YWHAH
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| Assignment of the brain 14-3-3 protein gene to chromosome 22.
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| Minoshima S, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2049. 1991
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| 27 | YWHAB, YWHAH, YWHAZ
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| Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases.
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| Ichimura T, et al.
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| Proc Natl Acad Sci U S A 85 : 7084-7088. 1988
|