| 1 | CAMKK2, YWHAG
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| 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2)
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| Psenakova K, Petrvalska O, Kylarova S, Lentini Santo D, Kalabova D, Herman P, Obsilova V, Obsil T.
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| Biochim Biophys Acta Gen Subj. Jul;1862(7):1612-1625. doi: 10.1016/j.bbagen.2018.04.006. Epub 2018 Apr 10. 2018
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| 2 | EIEE56, YWHAG
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| De Novo Mutations in YWHAG Cause Early-Onset Epilepsy.
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| Guella I, McKenzie MB, Evans DM, Buerki SE, Toyota EB, Van Allen MI; Epilepsy Genomics Study, Suri M, Elmslie F; Deciphering Developmental Disorders Study, Simon MEH, van Gassen KLI, Héron D, Keren B, Nava C, Connolly MB, Demos M, Farrer MJ.
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| Am J Hum Genet 101(2):300-310. doi: 10.1016/j.ajhg.2017.07.004. 2017
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| 3 | WBS, YWHAG
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| Epilepsy is a possible feature in Williams-Beuren syndrome patients harboring typical deletions of the 7q11.23 critical region.
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| Nicita F, Garone G, Spalice A, Savasta S, Striano P, Pantaleoni C, Spartŕ MV, Kluger G, Capovilla G, Pruna D, Freri E, D'Arrigo S, Verrotti A.
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| Am J Med Genet A 170A(1):148-55. doi: 10.1002/ajmg.a.37410. Epub 2015 Oct 5.
2016
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| 4 | CSNK2A1, DOK7, RAC1, RAPSN, YWHAG
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| Protein kinase CK2 interacts at the neuromuscular synapse with Rapsyn, Rac1, 14-3-3γ, and Dok-7 proteins and phosphorylates the latter two.
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| Herrmann D, Straubinger M, Hashemolhosseini S.
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| J Biol Chem 290(37):22370-84. doi: 10.1074/jbc.M115.647610. Epub 2015 Jul 21.
2015
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| 5 | TP53, YWHAG
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| p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation.
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| Chen DY, Dai DF, Hua Y, Qi WQ.
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| Int J Oncol 46(2):818-24. doi: 10.3892/ijo.2014.2740. Epub 2014 Nov 7.
2015
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| 6 | WBS, YWHAG
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| Smaller and larger deletions of the Williams Beuren syndrome region implicate genes involved in mild facial phenotype, epilepsy and autistic traits.
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| Fusco C, Micale L, Augello B, Teresa Pellico M, Menghini D, Alfieri P, Cristina Digilio M, Mandriani B, Carella M, Palumbo O, Vicari S, Merla G.
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| Eur J Hum Genet 22(1):64-70. doi: 10.1038/ejhg.2013.101. Epub 2013 Jun 12.
2014
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| 7 | TRPM4, YWHAG
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| Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death.
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| Cho CH, Kim E, Lee YS, Yarishkin O, Yoo JC, Park JY, Hong SG, Hwang EM.
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| Mol Brain 7:52. doi: 10.1186/s13041-014-0052-3.
2014
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| 8 | CXXC1, TCF3, YWHAG
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| Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.
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| Mai T, Pone EJ, Li G, Lam TS, Moehlman J, Xu Z, Casali P.
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| J Immunol 191(4):1895-906. doi: 10.4049/jimmunol.1300922. Epub 2013 Jul 12.
2013
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| 9 | RGS18, YWHAG
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| Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets.
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| Gegenbauer K, Elia G, Blanco-Fernandez A, Smolenski A.
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| Blood 119(16):3799-807. doi: 10.1182/blood-2011-11-390369. Epub 2012 Jan 10.
2012
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| 10 | YWHAG
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| Superhelical DNA as a preferential binding target of 14-3-3γ protein.
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| Brázda V, Cechová J, Coufal J, Rumpel S, Jagelská EB.
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| J Biomol Struct Dyn 30(4):371-8. doi: 10.1080/07391102.2012.682205.
2012
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| 11 | YWHAG
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| P53 suppresses expression of the 14-3-3 gamma oncogene.
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| Radhakrishnan VM, Putnam CW, Qi W, Martinez JD.
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| BMC Cancer 11:378. doi: 10.1186/1471-2407-11-378.
2011
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| 12 | MDM4, YWHAG
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| 14-3-3Gamma inhibition of MDMX-mediated p21 turnover independent of p53.
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| Lee JH, Lu H.
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| J Biol Chem 286(7):5136-42. doi: 10.1074/jbc.M110.190470. Epub 2010 Dec 9.
2011
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| 13 | DEL7Q1123, HIP1, YWHAG
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| Recurrent Distal 7q11.23 Deletion Including HIP1 and YWHAG Identified in Patients with Intellectual Disabilities, Epilepsy, and Neurobehavioral Problems.
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| Ramocki MB, Bartnik M, Szafranski P, Kołodziejska KE, Xia Z, Bravo J, Miller GS, Rodriguez DL, Williams CA, Bader PI, Szczepanik E, Mazurczak T, Antczak-Marach D, Coldwell JG, Akman CI, McAlmon K, Cohen MP, McGrath J, Roeder E, Mueller J, Kang SH, Bacino CA, Patel A, Bocian E, Shaw CA, Cheung SW, Mazurczak T, Stankiewicz P.
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| Am J Hum Genet 87(6):857-65. Epub 2010 Nov 25.PMID: 21109226 2010
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| 14 | YWHAG
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| Zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly.
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| Komoike Y, Fujii K, Nishimura A, Hiraki Y, Hayashidani M, Shimojima K, Nishizawa T, Higashi K, Yasukawa K, Saitsu H, Miyake N, Mizuguchi T, Matsumoto N, Osawa M, Kohno Y, Higashinakagawa T, Yamamoto T.
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| Genesis 48(4):233-43. doi: 10.1002/dvg.20607.
2010
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| 15 | YWHAG
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| 14-3-3 Gamma is required to enforce both the incomplete S phase and G2 DNA damage checkpoints.
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| Hosing AS, Kundu ST, Dalal SN.
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| Cell Cycle 7(20):3171-9. Epub 2008 Oct 21.
2008
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| 16 | YWHAG
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| Small heat shock protein Hsp20 (HspB6) as a partner of 14-3-3gamma.
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| Chernik IS, Seit-Nebi AS, Marston SB, Gusev NB.
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| Mol Cell Biochem 295(1-2):9-17. Epub 2006 Nov 16.
2007
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| 17 | YWHAQ, YWHAZ, YWHAG, CENPJ
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| CPAP interacts with 14-3-3 in a cell cycle-dependent manner.
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| Chen CY, Olayioye MA, Lindeman GJ, Tang TK.
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| Biochem Biophys Res Commun 342(4):1203-10. Epub 2006 Feb 24. 2006
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| 18 | YWHAQ, YWHAZ, YWHAG
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| The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein.
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| Satoh J, Onoue H, Arima K, Yamamura T.
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| J Neuropathol Exp Neurol 64(10):858-68. 2005
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| 19 | MLX, MLXIPL, YWHAB, YWHAG, YWHAZ, YWHAQ
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| The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3.
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| Merla G, Howald C, Antonarakis SE, Reymond A.
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| Hum Mol Genet 13(14):1505-14. Epub 2004 May 26. 2004
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| 20 | YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ, YWHAR, YWHAZ
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| 14-3-3 proteins block apoptosis and differentially regulate MAPK cascades.
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| Xing H, Zhang S, Weinheimer C, Kovacs A, Muslin AJ.
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| EMBO J 19(3):349-358 2000
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| 21 | YWHAG
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| Cloning, expression, and chromosomal mapping of the human 14-3-3gamma gene (YWHAG) to 7q11.23.
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| Horie M, et al.
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| Genomics 60(2):241-3 1999
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