Citations for
c-Yes enhances tumor migration and invasion via PI3K/AKT pathway in epithelial ovarian cancer.
Jin Y, Huang M, Wang Y, Yi C, Deng Y, Chen Y, Jiang L, Wang J, Shen Q, Liu R, QinghuaXi.
Exp Mol Pathol 101(1):50-7. doi: 10.1016/j.yexmp.2016.06.002. Epub 2016 Jun 8. 2016
YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cells.
Yoder SM, Dineen SL, Wang Z, Thurmond DC.
J Biol Chem 289(16):11476-87. doi: 10.1074/jbc.M114.559328. Epub 2014 Mar 7. 2014
Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth.
Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ.
Oncogene ncogene. 2013 Jan 14. doi: 10.1038/onc.2012.590. [Epub ahead of print] 2013
YES1 activation elicited by heat stress is anti-apoptotic in mouse pachytene spermatocytes.
Liang Y, Dong Y, Zhao J, Li W.
Biol Reprod 89(6):131. doi: 10.1095/biolreprod.113.112235. Print 2013 Dec. 2013
c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.
Xiao X, Mruk DD, Cheng CY.
Am J Physiol Endocrinol Metab 304(2):E145-59. doi: 10.1152/ajpendo.00422.2012. Epub 2012 Nov 20. Erratum in: Am J Physiol Endocrinol Metab. 2013 Mar 1;304(5): 2013
Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor.
Iida M, Brand TM, Campbell DA, Li C, Wheeler DL.
Oncogene 32(6):759-67. doi: 10.1038/onc.2012.90. Epub 2012 Mar 19. Erratum in: Oncogene. 2019 Mar;38(13):2435. 2013
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC.
Cell 151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Erratum in: Cell. 2013 Mar 28;153(1):267-70. 2012
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.
Xiao X, Mruk DD, Lee WM, Cheng CY.
Int J Biochem Cell Biol 43(4):651-65. doi: 10.1016/j.biocel.2011.01.008. Epub 2011 Jan 21. 2011
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.
Sato I, Obata Y, Kasahara K, Nakayama Y, Fukumoto Y, Yamasaki T, Yokoyama KK, Saito T, Yamaguchi N.
J Cell Sci 122(Pt 7):965-75. Epub 2009 Mar 3. 2009
Yes and PI3K bind CD95 to signal invasion of glioblastoma.
Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A.
Cancer Cell 13(3):235-48.PMID: 18328427 2008
Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: involvement in the early stages of hepatocarcinogenesis.
Nonomura T, Masaki T, Morishita A, Jian G, Uchida N, Himoto T, Izuishi K, Iwama H, Yoshiji H, Watanabe S, Kurokohchi K, Kuriyama S.
Int J Oncol 30(1):105-11. 2007
Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation.
Martín-García JM, Luque I, Mateo PL, Ruiz-Sanz J, Cámara-Artigas A.
FEBS Lett 581(9):1701-6. Epub 2007 Mar 30. 2007
Activation of c-Yes in hepatocellular carcinoma: a preliminary study.
Feng H, Masaki T, Nonomura T, Morishita A, Jian G, Nakai S, Deguchi A, Uchida N, Himoto T, Iwama H, Usuki H, Wakabayashi H, Izuishi K, Yoshiji H, Kurokohchi K, Kuriyama S.
World J Gastroenterol 12(35):5743-5. No abstract available. 2006
Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events.
Werdich XQ, Penn JS.
Angiogenesis 8(4):315-26. Epub 2006 Jan 7. 2005
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal.
Annerén C, Cowan CA, Melton DA.
J Biol Chem 279(30):31590-8. Epub 2004 May 17. 2004
Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas.
Nakakuki K, Imoto I, Pimkhaokham A, Fukuda Y, Shimada Y, Imamura M, Amagasa T, Inazawa J.
Carcinogenesis 23(1):19-24. 2002
Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.
McInnes LA, Service SK, Reus VI, Barnes G, Charlat O, Jawahar S, Lewitzky S, Yang Q, Duong Q, Spesny M, Araya C, Araya X, Gallegos A, Meza L, Molina J, Ramirez R, Mendez R, Silva S, Fournier E, Batki SL, Mathews CA, Neylan T, Glatt CE, Escamilla MA, Luo D, Gajiwala P, Song T, Crook S, Nguyen JB, Roche E, Meyer JM, Leon P, Sandkuijl LA, Freimer NB, Chen H.
Proc Natl Acad Sci U S A 98(20):11485-90. 2001
Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylation.
Sun G, Sharma AK, Budde RJ.
Oncogene 17(12):1587-95.PMID: 9794236 1998
Chromosomal reassignment : YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18.
Silverman GA, et al.
Genomics 15 : 442-445. 1993
20BCL2, YES1
C-yes and bcl-2 genes located on 18q21.3 in a follicular lymphoma cell line carrying a T(14;18) chromosomal translocation.
Ohno H, et al.
Int J Cancer 39 : 785-788. 1987
Location of the c-yes gene on the human chromosome and its expression in various tissues.
Semba K, et al.
Science 227 : 1038-1040. 1985
Localization of the human cellular oncogene c-yes-1 to chromosome 18 band q21.
Yoshida MC, et al.
(HGM8) Cytogenet Cell Genet 40 : 786. 1985
23YES1, D18S3
DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome.
Mattei MG, et al.
Hum Genet 69 : 268-271. 1985