Citations for
1RAD51B, RAD51D, RAD51c, XRCC2, XRCC3
Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
Berti M, Teloni F, Mijic S, Ursich S, Fuchs J, Palumbieri MD, Krietsch J, Schmid JA, Garcin EB, Gon S, Modesti M, Altmeyer M, Lopes M.
Nat Commun. Jul 15;11(1):3531. doi: 10.1038/s41467-020-17324-z. 2020
2RAD51B, RAD51D, RAD51c, XRCC2, XRCC3
Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells
Garcin EB, Gon S, Sullivan MR, Brunette GJ, Cian A, Concordet JP, Giovannangeli C, Dirks WG, Eberth S, Bernstein KA, Prakash R, Jasin M, Modesti M
PLoS Genet. Oct 4;15(10):e1008355. doi: 10.1371/journal.pgen.1008355. 2019
3SPGF50, XRCC2
XRCC2 mutation causes meiotic arrest, azoospermia and infertility
Yang Y, Guo J, Dai L, Zhu Y, Hu H, Tan L, Chen W, Liang D, He J, Tu M, Wang K, Wu L.
J Med Genet. Sep;55(9):628-636. doi: 10.1136/jmedgenet-2017-105145. Epub 2018 Jul 24 2018
4XRCC2
XRCC2 Regulates Replication Fork Progression during dNTP Alterations
Saxena S, Somyajit K, Nagaraju G.
Cell Rep. Dec 18;25(12):3273-3282.e6. doi: 10.1016/j.celrep.2018.11.085. 2018
5RAD51B, RAD51D, RAD51c, XRCC2, XRCC3
Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers
Golmard L, Castéra L, Krieger S, Moncoutier V, Abidallah K, Tenreiro H, Laugé A, Tarabeux J, Millot GA, Nicolas A, Laé M, Abadie C, Berthet P, Polycarpe F, Frébourg T, Elan C, de Pauw A, Gauthier-Villars M, Buecher B, Stern MH, Stoppa-Lyonnet D, Vaur D, Houdayer C.
Eur J Hum Genet Dec;25(12):1345-1353. doi: 10.1038/s41431-017-0021-2. Epub 2017 Nov 8. 2017
6BRCA1, FANCR, FANCS, FANCT, FANCU, FANCV, MAD2L2, RAD51, RAD51B, RAD51C, RAD51D, REV3L, UBE2T, XRCC2
Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia.
Mamrak NE, Shimamura A, Howlett NG.
Blood Rev lood Rev. 2016 Oct 13. pii: S0268-960X(16)30054-6. doi: 10.1016/j.blre.2016.10.002. Review. 2016
7XRCC2, XRCC4, ZNF281
ZNF281 contributes to the DNA damage response by controlling the expression of XRCC2 and XRCC4.
Pieraccioli M, Nicolai S, Antonov A, Somers J, Malewicz M, Melino G, Raschellŕ G.
Oncogene 35(20):2592-601. doi: 10.1038/onc.2015.320. Epub 2015 Aug 24. 2016
8FANCU, XRCC2
Complementation of hypersensitivity to DNA interstrand crosslinking agents demonstrates that XRCC2 is a Fanconi anaemia gene. 2016 PMID:
Park JY, Virts EL, Jankowska A, Wiek C, Othman M, Chakraborty SC, Vance GH, Alkuraya FS, Hanenberg H, Andreassen PR.
J Med Genet. Oct;53(10):672-680. doi: 10.1136/jmedgenet-2016-103847. Epub 2016 May 20. 2016
9XRCC2
XRCC2 promotes colorectal cancer cell growth, regulates cell cycle progression, and apoptosis
Xu K, Song X, Chen Z, Qin C, He Y, Zhan W.
Medicine (Baltimore). Dec;93(28):e294. doi: 10.1097/MD.0000000000000294. 2014
10RAD51B, RAD51C, RAD51D, XRCC2, XRCC3
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy.
Rodrigue A, Coulombe Y, Jacquet K, Gagné JP, Roques C, Gobeil S, Poirier G, Masson JY.
J Cell Sci 126(Pt 1):348-59. doi: 10.1242/jcs.114595. Epub 2012 Oct 29. 2013
11ATR, HELQ, RAD51A, RAD51B, RAD51C, XRCC2
Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs.
Takata K, Reh S, Tomida J, Person MD, Wood RD.
Nat Commun 4:2338. doi: 10.1038/ncomms3338. 2013
12XRCC2, XRCC3
Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway
Chun J, Buechelmaier ES, Powell SN.
Mol Cell Biol. Jan;33(2):387-95. doi: 10.1128/MCB.00465-12. Epub 2012 Nov 12. 2013
13XRCC2
Rare variants in XRCC2 as breast cancer susceptibility alleles.
Hilbers FS, Wijnen JT, Hoogerbrugge N, Oosterwijk JC, Collee MJ, Peterlongo P, Radice P, Manoukian S, Feroce I, Capra F, Couch FJ, Wang X, Guidugli L, Offit K, Shah S, Campbell IG, Thompson ER, James PA, Trainer AH, Gracia J, Benitez J, van Asperen CJ, Devilee P.
J Med Genet 49(10):618-20. doi: 10.1136/jmedgenet-2012-101191. 2012
14RAD51, XRCC1, XRCC2
Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
Cappelli E, Townsend S, Griffin C, Thacker J.
Exp Cell Res 317(8):1203-13. Epub 2011 Jan 27. 2011
15XRCC2
A role for XRCC2 gene polymorphisms in breast cancer risk and survival.
Lin WY, Camp NJ, Cannon-Albright LA, Allen-Brady K, Balasubramanian S, Reed MW, Hopper JL, Apicella C, Giles GG, Southey MC, Milne RL, Arias-Pérez JI, Menéndez-Rodríguez P, Benítez J, Grundmann M, Dubrowinskaja N, Park-Simon TW, Dörk T, Garcia-Closas M, Figueroa J, Sherman M, Lissowska J, Easton DF, Dunning AM, Rajaraman P, Sigurdson AJ, Doody MM, Linet MS, Pharoah PD, Schmidt MK, Cox A.
J Med Genet 48(7):477-84. Epub 2011 May 31. 2011
16RAD51B, RAD51C, RAD51D, XRCC2, XRCC3
RAD51 paralogs: roles in DNA damage signalling, recombinational repair and tumorigenesis.
Suwaki N, Klare K, Tarsounas M.
Semin Cell Dev Biol 22(8):898-905. doi: 10.1016/j.semcdb.2011.07.019. Epub 2011 Jul 28. Review. 2011
17RAD51, XRCC2
The importance of XRCC2 in RAD51-related DNA damage repair.
Tambini CE, Spink KG, Ross CJ, Hill MA, Thacker J.
DNA Repair (Amst) 9(5):517-25. doi: 10.1016/j.dnarep.2010.01.016. Epub 2010 Feb 26. 2010
18BRCA2, XRCC2
Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair.
Savolainen L, Helleday T.
Nucleic Acids Res 37(2):405-12. Epub 2008 Nov 29. 2009
19XRCC2
Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.
Pooley KA, Baynes C, Driver KE, Tyrer J, Azzato EM, Pharoah PD, Easton DF, Ponder BA, Dunning AM.
Cancer Epidemiol Biomarkers Prev 17(12):3482-9. 2008
20XRCC2
A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage.
Danoy P, Sonoda E, Lathrop M, Takeda S, Matsuda F.
Biochem Biophys Res Commun 352(3):763-8. Epub 2006 Nov 27. 2007
21XRCC2
Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
Moreno V, Gemignani F, Landi S, Gioia-Patricola L, Chabrier A, Blanco I, González S, Guino E, Capellŕ G, Canzian F.
Clin Cancer Res 12(7 Pt 1):2101-8. 2006
22RAD51B, RAD51C, RAD51D, XRCC2, XRCC3
The RAD51 gene family, genetic instability and cancer.
Thacker J.
Cancer Lett 219(2):125-35. Review. 2005
23XRCC2
A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer.
Rafii S, O'Regan P, Xinarianos G, Azmy I, Stephenson T, Reed M, Meuth M, Thacker J, Cox A.
Hum Mol Genet 11(12):1433-8. 2002
24XRCC2
XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding.
O'Regan P, Wilson C, Townsend S, Thacker J.
J Biol Chem 276(25):22148-53. 2001
25XRCC2
Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination.
Johnson RD, et al.
Nature 401(6751):397-9 1999
26XRCC2
The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.
Cartwright R, et al.
Nucleic Acids Res 26 : 3084-3089. 1998
27XRCC2
The XRCC2 DNA repair gene : identification of a positional candidate.
Tambini CE, et al.
Genomics 41 : 84-92. 1997
28XRCC2
Assignment of the XRCC2 human DNA repair gene to chromosome 7q36 by complementation analysis.
Jones NJ, et al.
Genomics 26 : 619-622. 1995
29XRCC2
Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents.
Thacker J, et al.
Hum Mol Genet 4 : 113-120. 1995