| 1 | XRCC1
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| PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks.
|
| Kordon MM, Szczurek A, Berniak K, Szelest O, Solarczyk K, Tworzydło M, Wachsmann-Hogiu S, Vaahtokari A, Cremer C, Pederson T, Dobrucki JW.
|
| FASEB J ASEB J. 2018 Sep 27:fj201801379R. doi: 10.1096/fj.201801379R. [Epub ahead of print]
2018
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| 2 | APTX, XRCC1
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| XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity.
|
| Horton JK, Stefanick DF, Çağlayan M, Zhao ML, Janoshazi AK, Prasad R, Gassman NR, Wilson SH.
|
| DNA Repair (Amst) 64:26-33. doi: 10.1016/j.dnarep.2018.02.004. Epub 2018 Feb 15.
2018
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| 3 | XRCC1
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| Meta-analysis of associations between XRCC1 gene polymorphisms and susceptibility to systemic lupus erythematosus and rheumatoid arthritis.
|
| Zhang MY, Yang XK, Lv TT, Wu J, Xu SZ, Wang JB, Pan HF, Ye DQ.
|
| Int J Rheum Dis 21(1):179-185. doi: 10.1111/1756-185X.12966. Epub 2017 Feb 15. Review.
2018
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| 4 | SCAR26, XRCC1
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| XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
|
| Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD; Care4Rare Canada Consortium, Yoon G, Caldecott KW.
|
| Nature 541(7635):87-91. doi: 10.1038/nature20790. Epub 2016 Dec 21.
2017
|
| 5 | CSNK2A2, PNKP, XRCC1
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| XRCC1-mediated repair of strand breaks independent of PNKP binding.
|
| Horton JK, Stefanick DF, Zhao ML, Janoshazi AK, Gassman NR, Seddon HJ, Wilson SH.
|
| DNA Repair (Amst) 60:52-63. doi: 10.1016/j.dnarep.2017.10.007. Epub 2017 Oct 19.
2017
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| 6 | PNKP, XRCC1
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| XRCC1-mediated repair of strand breaks independent of PNKP binding.
|
| Horton JK, Stefanick DF, Zhao ML, Janoshazi AK, Gassman NR, Seddon HJ, Wilson SH.
|
| DNA Repair (Amst) 60:52-63. doi: 10.1016/j.dnarep.2017.10.007. Epub 2017 Oct 19.
2017
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| 7 | XRCC1
|
| Role of the oxidized form of XRCC1 in protection against extreme oxidative stress.
|
| Horton JK, Seddon HJ, Zhao ML, Gassman NR, Janoshazi AK, Stefanick DF, Wilson SH.
|
| Free Radic Biol Med 107:292-300. doi: 10.1016/j.freeradbiomed.2017.02.005. Epub 2017 Feb 4.
2017
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| 8 | PARP1, PARP2, PNKP, XRCC1
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| Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
|
| Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.
|
| Nucleic Acids Res 45(5):2546-2557. doi: 10.1093/nar/gkw1246.
2017
|
| 9 | SMARCA5, XRCC1
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| SNF2H interacts with XRCC1 and is involved in repair of H2O2-induced DNA damage.
|
| Kubota Y, Shimizu S, Yasuhira S, Horiuchi S.
|
| DNA Repair (Amst) 43:69-77. doi: 10.1016/j.dnarep.2016.03.010. Epub 2016 May 19.
2016
|
| 10 | XRCC1
|
| Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
|
| Kirby TW, Gassman NR, Smith CE, Pedersen LC, Gabel SA, Sobhany M, Wilson SH, London RE.
|
| Sci Rep 5:13405. doi: 10.1038/srep13405.
2015
|
| 11 | HSP90AA1, POLB, XRCC1
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| HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.
|
| Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW.
|
| Nat Commun 5:5513. doi: 10.1038/ncomms6513.
2014
|
| 12 | REV1, XRCC1
|
| XRCC1 interaction with the REV1 C-terminal domain suggests a role in post replication repair.
|
| Gabel SA, DeRose EF, London RE.
|
| DNA Repair (Amst) 12(12):1105-13.
2013
|
| 13 | XRCC1
|
| Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
|
| Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH.
|
| DNA Repair (Amst) 12(9):774-85. doi: 10.1016/j.dnarep.2013.06.004. Epub 2013 Jul 18.
2013
|
| 14 | XRCC1
|
| Associations between three XRCC1 polymorphisms and glioma risk: a meta-analysis.
|
| Zhang H, Liu H, Knauss JL.
|
| Tumour Biol 34(5):3003-13. doi: 10.1007/s13277-013-0865-1. Epub 2013 May 29.
2013
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| 15 | LIG3, XRCC1
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| Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1).
|
| Boboila C, Oksenych V, Gostissa M, Wang JH, Zha S, Zhang Y, Chai H, Lee CS, Jankovic M, Saez LM, Nussenzweig MC, McKinnon PJ, Alt FW, Schwer B.
|
| Proc Natl Acad Sci U S A 109(7):2473-8. doi: 10.1073/pnas.1121470109. Epub 2012 Jan 30. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.
2012
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| 16 | XRCC1
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| X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.
|
| Han L, Mao W, Yu K.
|
| Proc Natl Acad Sci U S A 109(12):4604-8. doi: 10.1073/pnas.1120743109. Epub 2012 Mar 5.
2012
|
| 17 | ERCC2, XRCC1
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| XRCC1 and XPD DNA repair gene polymorphisms: a potential risk factor for glaucoma in the Pakistani population.
|
| Yousaf S, Khan MI, Micheal S, Akhtar F, Ali SH, Riaz M, Ali M, Lall P, Waheed NK, den Hollander AI, Ahmed A, Qamar R.
|
| Mol Vis. 17:1153-63. 2011
|
| 18 | RAD51, XRCC1, XRCC2
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| Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
|
| Cappelli E, Townsend S, Griffin C, Thacker J.
|
| Exp Cell Res 317(8):1203-13. Epub 2011 Jan 27. 2011
|
| 19 | PNKP, XRCC1
|
| Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1.
|
| Lu M, Mani RS, Karimi-Busheri F, Fanta M, Wang H, Litchfeld DW, Weinfeld M.
|
| Nucleic Acids Res 38(2):510-21. Epub 2009 Nov 12.PMID: 19910369 2010
|
| 20 | POLB, XRCC1
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| Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
|
| Cuneo MJ, London RE.
|
| Proc Natl Acad Sci U S A 107(15):6805-10. Epub 2010 Mar 29. 2010
|
| 21 | UNG, XRCC1
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| Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes.
|
| Akbari M, Solvang-Garten K, Hanssen-Bauer A, Lieske NV, Pettersen HS, Pettersen GK, Wilson DM 3rd, Krokan HE, Otterlei M.
|
| DNA Repair (Amst) 9(7):785-95. doi: 10.1016/j.dnarep.2010.04.002. Epub 2010 May 13.
2010
|
| 22 | APLF, PNKP, XRCC1
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| Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.
|
| Ali AA, Jukes RM, Pearl LH, Oliver AW.
|
| Nucleic Acids Res 37(5):1701-12. Epub 2009 Jan 20. 2009
|
| 23 | ARL6IP5, XRCC1
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| JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks.
|
| Wang S, Gong Z, Chen R, Liu Y, Li A, Li G, Zhou J.
|
| Nucleic Acids Res 37(6):1936-50. Epub 2009 Feb 10.
2009
|
| 24 | PRIM2, XRCC1
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| XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.
|
| Lévy N, Oehlmann M, Delalande F, Nasheuer HP, Van Dorsselaer A, Schreiber V, de Murcia G, Ménissier-de Murcia J, Maiorano D, Bresson A.
|
| Nucleic Acids Res 37(10):3177-88. Epub 2009 Mar 21.
2009
|
| 25 | XRCC1
|
| The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.
|
| Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ.
|
| Nat Neurosci. 12(8):973-80 2009
|
| 26 | XRCC1
|
| XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells.
|
| Kulkarni A, McNeill DR, Gleichmann M, Mattson MP, Wilson DM 3rd.
|
| Nucleic Acids Res 36(15):5111-21. Epub 2008 Aug 5.
2008
|
| 27 | XRCC1
|
| Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
|
| Chou WC, Wang HC, Wong FH, Ding SL, Wu PE, Shieh SY, Shen CY.
|
| EMBO J 27(23):3140-50. Epub 2008 Oct 30.
2008
|
| 28 | XRCC1, XRCC3
|
| Polymorphisms of the DNA repair genes XRCC1 and XRCC3 and risk of lung and colorectal cancer: a case-control study in a Southern Italian population.
|
| Improta G, Sgambato A, Bianchino G, Zupa A, Grieco V, La Torre G, Traficante A, Cittadini A.
|
| Anticancer Res 28(5B):2941-6.PMID: 19031937 2008
|
| 29 | APLF, XRCC1
|
| APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.
|
| Iles N, Rulten S, El-Khamisy SF, Caldecott KW.
|
| Mol Cell Biol 27(10):3793-803. Epub 2007 Mar 12. 2007
|
| 30 | XRCC1, PNKP
|
| XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates.
|
| Mani RS, Fanta M, Karimi-Busheri F, Silver E, Virgen CA, Caldecott KW, Cass CE, Weinfeld M.
|
| J Biol Chem 282(38):28004-13. Epub 2007 Jul 23. 2007
|
| 31 | XRCC1
|
| XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage.
|
| Levy N, Martz A, Bresson A, Spenlehauer C, de Murcia G, Menissier-de Murcia J.
|
| Nucleic Acids Res 34(1):32-41. Print 2006. 2006
|
| 32 | NCAPH, PARP1, XRCC1
|
| Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.
|
| Heale JT, Ball AR Jr, Schmiesing JA, Kim JS, Kong X, Zhou S, Hudson DF, Earnshaw WC, Yokomori K.
|
| Mol Cell 21(6):837-48. 2006
|
| 33 | XRCC1
|
| Association of XRCC1 gene polymorphisms with the susceptibility and chromosomal aberration of testicular germ cell tumors.
|
| Tsuchiya N, Mishina M, Narita S, Kumazawa T, Inoue T, Horikawa Y, Kakinuma H, Yuasa T, Matsuura S, Satoh S, Ogawa O, Habuchi T.
|
| Int J Oncol 28(5):1217-23. 2006
|
| 34 | XRCC1, LIG3
|
| Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells.
|
| Okano S, Lan L, Tomkinson AE, Yasui A.
|
| Nucleic Acids Res 33(1):422-9. Print 2005. 2005
|
| 35 | XRCC1
|
| Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer.
|
| Chacko P, Rajan B, Joseph T, Mathew BS, Pillai MR.
|
| Breast Cancer Res Treat 89(1):15-21. 2005
|
| 36 | XRCC1
|
| XRCC1 is required for DNA single-strand break repair in human cells.
|
| Brem R, Hall J.
|
| Nucleic Acids Res 33(8):2512-20. Print 2005. 2005
|
| 37 | APTX, XRCC1, TP53, PARP1
|
| Aprataxin, a novel protein that protects against genotoxic stress.
|
| Gueven N, Becherel OJ, Kijas AW, Chen P, Howe O, Rudolph JH, Gatti R, Date H, Onodera O, Taucher-Scholz G, Lavin MF.
|
| Hum Mol Genet 13(10):1081-93. Epub 2004 Mar 25. 2004
|
| 38 | XRCC1
|
| XRCC1 co-localizes and physically interacts with PCNA.
|
| Fan J, Otterlei M, Wong HK, Tomkinson AE, Wilson DM 3rd.
|
| Nucleic Acids Res 32(7):2193-201. Print 2004. 2004
|
| 39 | PARP1, XRCC1, APTX
|
| The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.
|
| Date H, Igarashi S, Sano Y, Takahashi T, Takahashi T, Takano H, Tsuji S, Nishizawa M, Onodera O.
|
| Biochem Biophys Res Commun 325(4):1279-85. 2004
|
| 40 | XRCC1
|
| Biophysical characterization of human XRCC1 and its binding to damaged and undamaged DNA.
|
| Mani RS, Karimi-Busheri F, Fanta M, Caldecott KW, Cass CE, Weinfeld M.
|
| Biochemistry 43(51):16505-14. 2004
|
| 41 | XRCC1
|
| A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment.
|
| Luo H, Chan DW, Yang T, Rodriguez M, Chen BP, Leng M, Mu JJ, Chen D, Songyang Z, Wang Y, Qin J.
|
| Mol Cell Biol. 24(19):8356-65. 2004
|
| 42 | XRCC1
|
| Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1.
|
| Marsin S, Vidal AE, Sossou M, Ménissier-de Murcia J, Le Page F, Boiteux S, de Murcia G, Radicella JP.
|
| J Biol Chem. 278(45):44068-74. 2003
|
| 43 | XRCC1
|
| XRCC1 polymorphisms and head and neck cancer.
|
| Olshan AF, Watson MA, Weissler MC, Bell DA.
|
| Cancer Lett 178(2):181-6. 2002
|
| 44 | XRCC1
|
| Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1.
|
| Schreiber V, Amé JC, Dollé P, Schultz I, Rinaldi B, Fraulob V, Ménissier-de Murcia J, de Murcia G.
|
| J Biol Chem. 277(25):23028-36. 2002
|
| 45 | PNKP, XRCC1
|
| XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair.
|
| Whitehouse CJ, Taylor RM, Thistlethwaite A, Zhang H, Karimi-Busheri F, Lasko DD, Weinfeld M, Caldecott KW.
|
| Cell 104(1):107-17. 2001
|
| 46 | APEX1, XRCC1
|
| XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions.
|
| Vidal AE, Boiteux S, Hickson ID, Radicella JP.
|
| EMBO J 20(22):6530-9. 2001
|
| 47 | XRCC1
|
| BRCT domain interactions in the heterodimeric DNA repair protein XRCC1-DNA ligase III.
|
| Dulic A, Bates PA, Zhang X, Martin SR, Freemont PS, Lindahl T, Barnes DE.
|
| Biochemistry. 40(20):5906-13. 2001
|
| 48 | ERCC2, XRCC1
|
| Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells.
|
| Duell EJ, Wiencke JK, Cheng TJ, Varkonyi A, Zuo ZF, Ashok TD, Mark EJ, Wain JC, Christiani DC, Kelsey KT.
|
| Carcinogenesis 21(5):965-71. 2000
|
| 49 | XRCC1
|
| Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck.
|
| Sturgis EM, Castillo EJ, Li L, Zheng R, Eicher SA, Clayman GL, Strom SS, Spitz MR, Wei Q.
|
| Carcinogenesis 20(11):2125-9 1999
|
| 50 | XRCC1
|
| Requirement for the Xrcc1 DNA base excision repair gene during early mouse development.
|
| Tebbs RS, Flannery ML, Meneses JJ, Hartmann A, Tucker JD, Thompson LH, Cleaver JE, Pedersen RA.
|
| Dev Biol. 208(2):513-29. 1999
|
| 51 | XRCC1, ZNF234, ZNF235, ZNF45
|
| Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse : evidence for orthologous genes.
|
| Shannon M, et al.
|
| Genomics 49 : 112-121. 1998
|
| 52 | XRCC1
|
| XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage.
|
| Masson M, Niedergang C, Schreiber V, Muller S, Menissier-de Murcia J, de Murcia G.
|
| Mol Cell Biol. 18(6):3563-71. 1998
|
| 53 | XRCC1, XRCC3, XRCC5
|
| Rare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity.
|
| Price EA, et al.
|
| Somat Cell Mol Genet 23 : 237-247. 1997
|
| 54 | BRCA1, DNTT, ECT2, MDM4, RAD9A, XPC, XRCC1
|
| From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair.
|
| Callebaut I, et al.
|
| FEBS Lett 400(1):25-30. 1997
|
| 55 | BRCA1, DNTT, ECT2, MDM4, RAD9A, XRCC1
|
| A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
|
| Bork P, et al.
|
| FASEB J 11(1):68-76. 1997
|
| 56 | XRCC1
|
| XRCC1 protein interacts with one of two distinct forms of DNA ligase III.
|
| Nash RA, Caldecott KW, Barnes DE, Lindahl T.
|
| Biochemistry. 36(17):5207-11. 1997
|
| 57 | LIG3, XRCC1
|
| XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro.
|
| Caldecott KW, et al.
|
| Nucleic Acids Res 24 : 4387-4394. 1996
|
| 58 | XRCC1
|
| Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
|
| Kubota Y, Nash RA, Klungland A, Schär P, Barnes DE, Lindahl T.
|
| EMBO J. 15(23):6662-70. 1996
|
| 59 | XRCC1
|
| Genomic sequence comparison of the human and mouse XRCC1 DNA repair gene regions.
|
| Lamerdin JE, et al.
|
| Genomics 25 : 547-554. 1995
|
| 60 | XRCC1
|
| An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III.
|
| Caldecott KW, et al.
|
| Mol Cell Biol 14 : 68-76. 1994
|
| 61 | ERCC1, ERCC2, XRCC1
|
| Complementation of repair gene mutations on the hemizygous chromosome 9 in CHO : a third repair gene on human chromosome 19.
|
| Thompson LH, et al.
|
| Genomics 5 : 670-679. 1989
|
| 62 | ERCC1, ERCC2, XRCC1
|
| Refined mapping ofthe three DNA repair genes, ERCC1, ERCC2, and XRCC1, on? human chromosome 19.
|
| Mohrenweiser HW, et al.
|
| Cytogenet Cell Genet 52 : 11-14. 1989
|
| 63 | ERCC1, ERCC2, XRCC1
|
| Regional assignment of DNA repair genes and a gene order for human chromosome 19.
|
| Bachinski LL, et al.
|
| Am J Hum Genet 43 : A135. 1988
|
| 64 | ERCC3, ERCC4, ERCC5, XRCC1
|
| Chromosomal assignments of human DNA repair genes that complement chinese hamster ovary (CHO) cell mutants.
|
| Siciliano MJ, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 691. 1987
|