1 | SEPTIN4, XIAP
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| The ARTS of Cell Death.
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| Koren E, Fuchs Y.
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| J Cell Death 12:1179066019836967. doi: 10.1177/1179066019836967. eCollection 2019.
2019
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2 | CYP1B1, PRKCE, XIAP
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| CYP1B1 prevents proteasome-mediated XIAP degradation by inducing PKCε activation and phosphorylation of XIAP
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| Baek HS, Kwon YJ, Ye DJ, Cho E, Kwon TU, Chun YJ
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| Biochim Biophys Acta Mol Cell Res. Dec;1866(12):118553. doi: 10.1016/j.bbamcr.2019.118553. Epub 2019 Sep 4. 2019
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3 | SEPTIN4, XIAP
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| ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
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| Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, Ben-Yosef R, Bar-Sela G, Fuchs Y.
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| Nat Commun 9(1):4582. doi: 10.1038/s41467-018-06941-4.
2018
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4 | USP11, XIAP
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| Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis.
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| Zhou Z, Luo A, Shrivastava I, He M, Huang Y, Bahar I, Liu Z, Wan Y.
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| EBioMedicine 15:48-61. doi: 10.1016/j.ebiom.2016.12.014. Epub 2016 Dec 23.
2017
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5 | XIAP
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| Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.
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| Hou Y, Allan LA, Clarke PR.
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| J Cell Sci 130(2):502-511. doi: 10.1242/jcs.192310. Epub 2016 Dec 7.
2017
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6 | SERTAD1, XIAP
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| The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms.
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| Hu W, Yu X, Liu Z, Sun Y, Chen X, Yang X, Li X, Lam WK, Duan Y, Cao X, Steller H, Liu K, Huang P.
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| Elife 6. pii: e28021. doi: 10.7554/eLife.28021.
2017
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7 | BCL2, SEPTIN4, XIAP
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| Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis.
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| Edison N, Curtz Y, Paland N, Mamriev D, Chorubczyk N, Haviv-Reingewertz T, Kfir N, Morgenstern D, Kupervaser M, Kagan J, Kim HT, Larisch S.
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| Cell Rep 21(2):442-454. doi: 10.1016/j.celrep.2017.09.052.
2017
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8 | XIAP
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| Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.
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| Wicki S, Gurzeler U, Wei-Lynn Wong W, Jost PJ, Bachmann D, Kaufmann T.
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| Cell Death Dis 7(10):e2422. doi: 10.1038/cddis.2016.311.
2016
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9 | SERTAD1, XIAP
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| Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.
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| Li C, Jung S, Yang Y, Kim KI, Lim JS, Cheon CI, Lee MS.
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| Int J Oncol 48(6):2639-46. doi: 10.3892/ijo.2016.3454. Epub 2016 Mar 24.
2016
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10 | BIRC5, FOXM1, XIAP
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| FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance.
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| Nestal de Moraes G, Delbue D, Silva KL, Robaina MC, Khongkow P, Gomes AR, Zona S, Crocamo S, Mencalha AL, Magalhães LM, Lam EW, Maia RC.
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| Cell Signal 27(12):2496-505. doi: 10.1016/j.cellsig.2015.09.013. Epub 2015 Sep 25.
2015
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11 | XIAP
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| Role of X-Linked Inhibitor of Apoptosis as a Prognostic Marker and Therapeutic Target in Papillary Thyroid Carcinoma.
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| Hussain AR, Bu R, Ahmed M, Jehan Z, Beg S, Al-Sobhi S, Al-Dayel F, Siraj AK, Uddin S, Al-Kuraya KS.
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| J Clin Endocrinol Metab 100(7):E974-85. doi: 10.1210/jc.2014-4356. Epub 2015 May 14.
2015
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12 | XIAP, XLP2
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| Symptomatic males and female carriers in a large Caucasian kindred with XIAP deficiency.
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| Dziadzio M, Ammann S, Canning C, Boyle F, Hassan A, Cale C, Elawad M, Fiil BK, Gyrd-Hansen M, Salzer U, Speckmann C, Grimbacher B.
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| J Clin Immunol 35(5):439-44. doi: 10.1007/s10875-015-0166-0. Epub 2015 May 6.
2015
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13 | BECN1, BIRC2, XIAP
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| XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation.
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| Lin F, Ghislat G, Luo S, Renna M, Siddiqi F, Rubinsztein DC.
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| Hum Mol Genet 24(10):2899-913. doi: 10.1093/hmg/ddv052. Epub 2015 Feb 10.
2015
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14 | XIAP
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| Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
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| Aoto K, Trainor PA.
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| Hum Mol Genet 24(3):698-713. doi: 10.1093/hmg/ddu489. Epub 2014 Oct 6.
2015
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15 | MAP2K5, MAP3K3, XIAP
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| Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1.
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| Takeda AN, Oberoi-Khanuja TK, Glatz G, Schulenburg K, Scholz RP, Carpy A, Macek B, Remenyi A, Rajalingam K.
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| EMBO J 33(16):1784-801. doi: 10.15252/embj.201487808. Epub 2014 Jun 28.
2014
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16 | STAG2, THOC2, XIAP
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| Definition of minimal duplicated region encompassing the XIAP and STAG2 genes in the Xq25 microduplication syndrome.
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| Di Benedetto D, Musumeci SA, Avola E, Alberti A, Buono S, Scuderi C, Grillo L, Galesi O, Spalletta A, Giudice ML, Luciano D, Vinci M, Bianca S, Romano C, Fichera M.
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| Am J Med Genet A 164A(8):1923-30. doi: 10.1002/ajmg.a.36570. Epub 2014 Apr 14.
2014
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17 | RIPK3, XIAP
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| XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.
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| Yabal M, Müller N, Adler H, Knies N, Groß CJ, Damgaard RB, Kanegane H, Ringelhan M, Kaufmann T, Heikenwälder M, Strasser A, Groß O, Ruland J, Peschel C, Gyrd-Hansen M, Jost PJ.
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| Cell Rep 7(6):1796-808. doi: 10.1016/j.celrep.2014.05.008. Epub 2014 May 29.
2014
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18 | BIRC2, RHOA, XIAP
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| A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation.
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| Hornburger MC, Mayer BA, Leonhardt S, Willer EA, Zahler S, Beyerle A, Rajalingam K, Vollmar AM, Fürst R.
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| FASEB J 28(4):1938-46. doi: 10.1096/fj.13-235754. Epub 2013 Dec 26. 2014
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19 | HTRA2, XIAP
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| Omi/HtrA2 and XIAP are components of platelet apoptosis signalling.
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| Winkler J, Rand ML, Schmugge M, Speer O.
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| Thromb Haemost 109(3). [Epub ahead of print]
2013
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20 | PTK2, PTK2B, XIAP
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| XIAP reverses various functional activities of FRNK in endothelial cells.
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| Ahn S, Kim HJ, Chi SG, Park H.
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| Biochem Biophys Res Commun 419(2):419-24. doi: 10.1016/j.bbrc.2012.02.037. Epub 2012 Feb 14.
2012
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21 | ARHGDIA, XIAP
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| RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.
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| Yu J, Zhang D, Liu J, Li J, Yu Y, Wu XR, Huang C.
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| J Biol Chem 287(17):13752-60. doi: 10.1074/jbc.M111.337469. Epub 2012 Mar 5.
2012
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22 | LYP, SH2D1A, XIAP, XLP2
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| Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency).
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| Pachlopnik Schmid J, Canioni D, Moshous D, Touzot F, Mahlaoui N, Hauck F, Kanegane H, Lopez-Granados E, Mejstrikova E, Pellier I, Galicier L, Galambrun C, Barlogis V, Bordigoni P, Fourmaintraux A, Hamidou M, Dabadie A, Le Deist F, Haerynck F, Ouachée-Chardin M, Rohrlich P, Stephan JL, Lenoir C, Rigaud S, Lambert N, Milili M, Schiff C, Chapel H, Picard C, de Saint Basile G, Blanche S, Fischer A, Latour S.
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| Blood 117(5):1522-9. Epub 2010 Nov 30.
2011
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23 | BIRC2, BIRC3, XIAP
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| Inhibitor of apoptosis proteins as novel targets in inflammatory processes.
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| Mayer BA, Rehberg M, Erhardt A, Wolf A, Reichel CA, Kracht M, Krombach F, Tiegs G, Zahler S, Vollmar AM, Fürst R.
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| Arterioscler Thromb Vasc Biol 31(10):2240-50. Epub 2011 Aug 4.
2011
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24 | TRIM32, XIAP
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| TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).
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| Ryu YS, Lee Y, Lee KW, Hwang CY, Maeng JS, Kim JH, Seo YS, You KH, Song B, Kwon KS.
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| J Biol Chem 286(29):25729-38. Epub 2011 May 31.
2011
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25 | CD40LG, XIAP
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| Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG.
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| Rigaud S, Lopez-Granados E, Sibéril S, Gloire G, Lambert N, Lenoir C, Synaeve C, Stacey M, Fugger L, Stephan JL, Fischer A, Picard C, Durandy A, Chapel H, Latour S.
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| Blood 118(2):252-61. Epub 2011 May 4.
2011
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26 | BIRC2, BIRC3, VGLL4, XIAP
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| A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration.
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| Jin HS, Park HS, Shin JH, Kim DH, Jun SH, Lee CJ, Lee TH.
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| Biochem Biophys Res Commun 412(3):454-9. Epub 2011 Aug 4.
2011
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27 | ARHGDIA, XIAP
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| X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton.
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| Liu J, Zhang D, Luo W, Yu Y, Yu J, Li J, Zhang X, Zhang B, Chen J, Wu XR, Rosas-Acosta G, Huang C.
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| J Biol Chem 286(18):15630-40. doi: 10.1074/jbc.M110.176982. Epub 2011 Mar 14.
2011
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28 | XIAP
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| XIAP as a ubiquitin ligase in cellular signaling.
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| Galbán S, Duckett CS.
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| Cell Death Differ 17(1):54-60. Epub .
2010
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29 | HAX1, XIAP
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| Molecular interaction between HAX-1 and XIAP inhibits apoptosis.
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| Kang YJ, Jang M, Park YK, Kang S, Bae KH, Cho S, Lee CK, Park BC, Chi SW, Park SG.
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| Biochem Biophys Res Commun 393(4):794-9. Epub 2010 Feb 18.PMID: 20171186 2010
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30 | CCS, XIAP
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| Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.
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| Brady GF, Galbán S, Liu X, Basrur V, Gitlin JD, Elenitoba-Johnson KS, Wilson TE, Duckett CS.
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| Mol Cell Biol 30(8):1923-36. Epub 2010 Feb 12.PMID: 20154138 2010
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31 | GZMM, XIAP
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| Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells.
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| Hu D, Liu S, Shi L, Li C, Wu L, Fan Z.
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| J Biol Chem 285(24):18326-35. Epub 2010 Apr 20.PMID: 20406824 2010
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32 | PTK2, XIAP
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| XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK.
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| Ahn S, Park H.
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| Biochem Biophys Res Commun 399(2):256-61. Epub 2010 Jul 22.PMID: 20655298 2010
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33 | DIABLO, XIAP
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| Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation.
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| Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J.
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| Cell Death Differ 17(10):1613-23. Epub 2010 Apr 16.
2010
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34 | CFLAR, XIAP
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| Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
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| Wilson TR, McEwan M, McLaughlin K, Le Clorennec C, Allen WL, Fennell DA, Johnston PG, Longley DB.
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| Oncogene 28(1):63-72. Epub 2008 Sep 29. 2009
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35 | BIIRC2, BIRC3, XIAP
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| cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation.
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| Jin HS, Lee DH, Kim DH, Chung JH, Lee SJ, Lee TH.
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| Cancer Res 69(5):1782-91. Epub 2009 Feb 17. 2009
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36 | XIAP
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| S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.
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| Tsang AH, Lee YI, Ko HS, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KK.
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| Proc Natl Acad Sci U S A 106(12):4900-5. Epub 2009 Mar 9. Erratum in: Proc Natl Acad Sci U S A. 2009 May 26;106(21):8791.
2009
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37 | COMMD1, XIAP
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| COMMD1 expression is controlled by critical residues that determine XIAP binding.
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| Maine GN, Mao X, Muller PA, Komarck CM, Klomp LW, Burstein E.
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| Biochem J 417(2):601-9.
2009
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38 | XIAP
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| X-linked Inhibitor of Apoptosis Protein (XIAP) Regulates PTEN Ubiquitination, Content, and Compartmentalization.
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| Van Themsche C, Leblanc V, Parent S, Asselin E.
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| J Biol Chem 284(31):20462-6. Epub 2009 May 27.
2009
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39 | XIAP
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| XIAP discriminates between type I and type II FAS-induced apoptosis.
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| Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T.
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| Nature 460(7258):1035-9. Epub 2009 Jul 22.
2009
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40 | NOD1, NOD2, RIPK2, XIAP
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| XIAP mediates NOD signaling via interaction with RIP2.
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| Krieg A, Correa RG, Garrison JB, Le Negrate G, Welsh K, Huang Z, Knoefel WT, Reed JC.
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| Proc Natl Acad Sci U S A 106(34):14524-9. Epub 2009 Aug 10.PMID: 19667203 2009
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41 | XIAP
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| XIAP effects on retinal detachment-induced photoreceptor apoptosis
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| Zadro-Lamoureux LA, Zacks DN, Baker AN, Zheng QD, Hauswirth WW, Tsilfidis C.
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| Invest Ophthalmol Vis Sci. 50(4):1530 2009
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42 | XIAP
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| p34SEI-1 inhibits apoptosis through the stabilization of the X-linked inhibitor of apoptosis protein: p34SEI-1 as a novel target for anti-breast cancer strategies.
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| Hong SW, Kim CJ, Park WS, Shin JS, Lee SD, Ko SG, Jung SI, Park IC, An SK, Lee WK, Lee WJ, Jin DH, Lee MS.
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| Cancer Res. 69(3):741-6. 2009
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43 | BIRC5, LAMTOR5, XIAP
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| Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma.
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| Krepela E, Dankova P, Moravcikova E, Krepelova A, Prochazka J, Cermak J, Schützner J, Zatloukal P, Benkova K.
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| Int J Oncol 35(6):1449-62.PMID: 19885569 2009
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44 | BIRC2, BIRC3, XIAP
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| cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation.
|
| Jin HS, Lee DH, Kim DH, Chung JH, Lee SJ, Lee TH.
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| Cancer Res 69(5):1782-91. Epub 2009 Feb 17.
2009
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45 | AATF, XIAP
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| Che-1 activates XIAP expression in response to DNA damage.
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| Bruno T, Iezzi S, De Nicola F, Di Padova M, Desantis A, Scarsella M, Di Certo MG, Leonetti C, Floridi A, Passananti C, Fanciulli M.
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| Cell Death Differ 15(3):515-20. Epub 2007 Nov 30. 2008
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46 | XIAP
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| XIAP regulates intracellular ROS by enhancing antioxidant gene expression.
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| Resch U, Schichl YM, Sattler S, de Martin R.
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| Biochem Biophys Res Commun 375(1):156-61. Epub 2008 Aug 8. 2008
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47 | RAF1, STUB1, XIAP
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| X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility.
|
| Dogan T, Harms GS, Hekman M, Karreman C, Oberoi TK, Alnemri ES, Rapp UR, Rajalingam K.
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| Nat Cell Biol 10(12):1447-55. Epub 2008 Nov 16. Erratum in: Nat Cell Biol. 2009 Jan;11(1):110. 2008
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48 | XIAP
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| XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination of MEKK2.
|
| Winsauer G, Resch U, Hofer-Warbinek R, Schichl YM, de Martin R.
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| Cell Signal. 20(11):2107-12. 2008
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49 | AIFM1, XIAP
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| Apoptosis-inducing factor is a target for ubiquitination through interaction with XIAP.
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| Wilkinson JC, Wilkinson AS, Galbán S, Csomos RA, Duckett CS.
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| Mol Cell Biol 28(1):237-47. Epub 2007 Oct 29.PMID: 17967870 2008
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50 | XIAP
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| X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation.
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| Kairisalo M, Korhonen L, Blomgren K, Lindholm D.
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| Biochem Biophys Res Commun 364(1):138-44. Epub 2007 Oct 4. 2007
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51 | KCNJ6, TAB1, XIAP
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| XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
|
| Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H.
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| Mol Cell 26(5):689-702. 2007
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52 | CASP3, CASP9, XIAP
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| Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.
|
| Denault JB, Eckelman BP, Shin H, Pop C, Salvesen GS.
|
| Biochem J 405(1):11-9.
2007
|
53 | XIAP
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| Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.
|
| Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG.
|
| J Biol Chem. 282(36):26202-9. 2007
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54 | XIAP
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| Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection.
|
| Dohi T, Xia F, Altieri DC.
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| Mol Cell. 27(1):17-28. 2007
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55 | XIAP
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| X-linked inhibitor of apoptosis regulates T cell effector function.
|
| Zehntner SP, Bourbonnière L, Moore CS, Morris SJ, Methot D, St Jean M, Lacasse E, Hebb AL, Robertson GS, Durkin J, Gillard JW, Owens T.
|
| J Immunol 179(11):7553-60.PMID: 18025200 2007
|
56 | AFP, XIAP
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| Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
|
| Dudich E, Semenkova L, Dudich I, Denesyuk A, Tatulov E, Korpela T.
|
| FEBS J 273(16):3837-49. Epub 2006 Jul 26. 2006
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57 | LYP, XIAP, XLP2
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| XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome.
|
| Rigaud S, Fondaneche MC, Lambert N, Pasquier B, Mateo V, Soulas P, Galicier L, Le Deist F, Rieux-Laucat F, Revy P, Fischer A, de Saint Basile G, Latour S.
|
| Nature 444(7115):110-4. 2006
|
58 | XIAP
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| XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders.
|
| Mufti AR, Burstein E, Csomos RA, Graf PC, Wilkinson JC, Dick RD, Challa M, Son JK, Bratton SB, Su GL, Brewer GJ, Jakob U, Duckett CS.
|
| Mol Cell. 21(6):775-85. 2006
|
59 | XIAP
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| XIAP-mediated neuroprotection in retinal ischemia.
|
| Renwick J, Narang MA, Coupland SG, Xuan JY, Baker AN, Brousseau J, Petrin D, Munger R, Leonard BC, Hauswirth WW, Korneluk RG, Tsilfidis C.
|
| Gene Ther. 13(4):339-47. 2006
|
60 | CASP9, DIABLO, XIAP
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| X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
|
| Morizane Y, Honda R, Fukami K, Yasuda H.
|
| J Biochem (Tokyo) 137(2):125-32. 2005
|
61 | MAP3K7, MAPK8, XIAP
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| X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
|
| Kaur S, Wang F, Venkatraman M, Arsura M.
|
| J Biol Chem 280(46):38599-608. Epub 2005 Sep 12. 2005
|
62 | XIAP
|
| X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
|
| Wang X, Zhu C, Wang X, Hagberg H, Korhonen L, Sandberg M, Lindholm D, Blomgren K.
|
| Neurobiol Dis 16(1):179-89. 2004
|
63 | COMMD1, COMMD8, XIAP
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| A novel role for XIAP in copper homeostasis through regulation of MURR1.
|
| Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, Wijmenga C, Brewer GJ, Nabel GJ, Duckett CS.
|
| EMBO J 23(1):244-54. Epub 2003 Dec 18. 2004
|
64 | BIRC2, BIRC3, XAF1, XIAP
|
| Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1.
|
| Perrelet D, Perrin FE, Liston P, Korneluk RG, MacKenzie A, Ferrer-Alcon M, Kato AC.
|
| J Neurosci 24(15):3777-85. 2004
|
65 | XIAP
|
| Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis.
|
| Galvan V, Kurakin AV, Bredesen DE.
|
| FEBS Lett. 558(1-3):57-62. 2004
|
66 | XIAP
|
| X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells.
|
| Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F.
|
| Cancer Res. 64(9):3006-8. 2004
|
67 | XIAP
|
| Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma.
|
| Shiraki K, Sugimoto K, Yamanaka Y, Yamaguchi Y, Saitou Y, Ito K, Yamamoto N, Yamanaka T, Fujikawa K, Murata K, Nakano T.
|
| Int J Mol Med 12(5):705-8. 2003
|
68 | DIABLO, XIAP
|
| Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac.
|
| Huang Y, Rich RL, Myszka DG, Wu H.
|
| J Biol Chem 278(49):49517-22. Epub 2003 Sep 25. 2003
|
69 | GSTP1, XIAP
|
| The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein.
|
| Hegde R, Srinivasula SM, Datta P, Madesh M, Wassell R, Zhang Z, Cheong N, Nejmeh J, Fernandes-Alnemri T, Hoshino S, Alnemri ES.
|
| J Biol Chem 278(40):38699-706. Epub 2003 Jul 15. 2003
|
70 | XIAP
|
| XIAP protects photoreceptors from n-methyl-n-nitrosourea-induced retinal degeneration.
|
| Petrin D, Baker A, Brousseau J, Coupland S, Liston P, Hauswirth WW, Komeluk RG, Tsilfidis C.
|
| Adv Exp Med Biol. 533:385-93. 2003
|
71 | ALS2CR2, XIAP
|
| ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis.
|
| Sanna MG, da Silva Correia J, Luo Y, Chuang B, Paulson LM, Nguyen B, Deveraux QL, Ulevitch RJ.
|
| J Biol Chem 277(34):30454-62. 2002
|
72 | HTRA2, XIAP
|
| HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.
|
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