| 1 | PKD1, WWTR1
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| Polycystin-1 regulates bone development through an interaction with the transcriptional coactivator TAZ
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| Merrick D, Mistry K, Wu J, Gresko N, Baggs JE, Hogenesch JB, Sun Z, Caplan MJ.
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| Hum Mol Genet. Jan 1;28(1):16-30. doi: 10.1093/hmg/ddy322. 2019
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| 2 | LEF1, RUNX2, WNT3, WWTR1
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| Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.
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| Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R.
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| Sci Rep 8(1):10375. doi: 10.1038/s41598-018-28711-4.
2018
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| 3 | CAMTA1, WWTR1
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| Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein.
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| Tanas MR, Ma S, Jadaan FO, Ng CK, Weigelt B, Reis-Filho JS, Rubin BP.
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| Oncogene 35(7):929-38. doi: 10.1038/onc.2015.148. Epub 2015 May 11.
2016
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| 4 | LIMK2, TESK1, WWTR1, YAP1
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| Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking.
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| Kim J, Jo H, Hong H, Kim MH, Kim JM, Lee JK, Heo WD, Kim J.
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| Nat Commun 6:6781. doi: 10.1038/ncomms7781.
2015
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| 5 | ARHGEF7, WWTR1, YAP1
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| Arhgef7 promotes activation of the Hippo pathway core kinase Lats.
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| Heidary Arash E, Song KM, Song S, Shiban A, Attisano L.
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| EMBO J 33(24):2997-3011. doi: 10.15252/embj.201490230.
2014
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| 6 | BMP4, WWTR1
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| BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ.
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| Lai D, Yang X.
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| Cell Signal 25(8):1720-8. doi: 10.1016/j.cellsig.2013.05.002. Epub 2013 May 11.
2013
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| 7 | KLF5, WWTR1
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| TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis.
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| Zhao D, Zhi X, Zhou Z, Chen C.
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| Carcinogenesis 33(1):59-67. Epub 2011 Oct 31.
2012
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| 8 | NFAT5, WWTR1
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| TAZ suppresses NFAT5 activity through tyrosine phosphorylation.
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| Jang EJ, Jeong H, Han KH, Kwon HM, Hong JH, Hwang ES.
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| Mol Cell Biol 32(24):4925-32. doi: 10.1128/MCB.00392-12. Epub 2012 Oct 8.
2012
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| 9 | CAMTA1, WWTR1
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| A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites.
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| Errani C, Zhang L, Sung YS, Hajdu M, Singer S, Maki RG, Healey JH, Antonescu CR.
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| Genes Chromosomes Cancer 50(8):644-53. doi: 10.1002/gcc.20886. Epub 2011 May 16.
2011
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| 10 | AMOT, AMOTL1, WWTR1, YAP1
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| Hippo pathway-independent restriction of TAZ and YAP by angiomotin.
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| Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W.
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| J Biol Chem 286(9):7018-26. Epub 2011 Jan 11. 2011
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| 11 | AMOT, AMOTL2, WWTR1, YAP1
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| Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.
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| Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei Q, Guan KL.
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| Genes Dev 25(1):51-63. 2011
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| 12 | WBP2, WWTR1, YAP1
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| WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ.
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| Chan SW, Lim CJ, Huang C, Chong YF, Gunaratne HJ, Hogue KA, Blackstock WP, Harvey KF, Hong W.
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| Oncogene 30(5):600-10. Epub 2010 Oct 25. 2011
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| 13 | WWTR1
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| TAZ is a novel oncogene in non-small cell lung cancer.
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| Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X.
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| Oncogene 30(18):2181-6. doi: 10.1038/onc.2010.606. Epub 2011 Jan 24.
2011
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| 14 | WWTR1, YAP1
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| Role of YAP/TAZ in mechanotransduction.
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| Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, Elvassore N, Piccolo S.
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| Nature 474(7350):179-83. doi: 10.1038/nature10137.
2011
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| 15 | SCRIB, WWTR1
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| The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.
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| Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S.
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| Cell 147(4):759-72. doi: 10.1016/j.cell.2011.09.048.
2011
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| 16 | WWTR1
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| The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.
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| Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD.
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| Genes Dev 25(24):2594-609. doi: 10.1101/gad.176800.111.
2011
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| 17 | NEK1, PKD2, WWTR1
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| Nek1 and TAZ interact to maintain normal levels of polycystin 2.
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| Yim H, Sung CK, You J, Tian Y, Benjamin T.
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| J Am Soc Nephrol 22(5):832-7. doi: 10.1681/ASN.2010090992. Epub 2011 Apr 7.
2011
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| 18 | WWTR1
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| Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization.
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| Strakova Z, Reed J, Ihnatovych I.
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| Biol Reprod 82(6):1112-8. doi: 10.1095/biolreprod.109.081844. Epub 2010 Feb 17.
2010
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| 19 | MYOD1, WWTR1
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| TAZ as a novel enhancer of MyoD-mediated myogenic differentiation.
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| Jeong H, Bae S, An SY, Byun MR, Hwang JH, Yaffe MB, Hong JH, Hwang ES.
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| FASEB J 24(9):3310-20. doi: 10.1096/fj.09-151324. Epub 2010 May 13.
2010
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| 20 | GLIS2, GLIS3, NPHP7, WWTR1
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| Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
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| Kang HS, Beak JY, Kim YS, Herbert R, Jetten AM.
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| Mol Cell Biol 29(10):2556-69. Epub 2009 Mar 9.
2009
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| 21 | WWTR1
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| A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells.
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| Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, Zeng Q, Hong W.
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| Cancer Res 68(8):2592-8.
2008
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| 22 | CTNNAL1, FLT1, GSTP1, LEP, PAPPA2, S100A8, WWTR1
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| Seven placental transcripts characterize HELLP-syndrome.
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| Buimer M, Keijser R, Jebbink JM, Wehkamp D, van Kampen AH, Boer K, van der Post JA, Ris-Stalpers C.
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| Placenta 29(5):444-53.
2008
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| 23 | WWTR1
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| TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.
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| Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL.
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| Mol Cell Biol 28(7):2426-36. Epub 2008 Jan 28.PMID: 18227151 2008
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| 24 | DCTN5, WWTR1
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| Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
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| Hossain Z, Ali SM, Ko HL, Xu J, Ng CP, Guo K, Qi Z, Ponniah S, Hong W, Hunziker W.
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| Proc Natl Acad Sci U S A 104(5):1631-6. Epub 2007 Jan 24.
2007
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| 25 | NPPA, TBX5, WWTR1, YY1AP1
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| A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome.
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| Murakami M, Nakagawa M, Olson EN, Nakagawa O.
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| Proc Natl Acad Sci U S A 102(50):18034-9. Epub 2005 Dec 6. 2005
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