| 1 | SFRP1, WNT7A
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| Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex.
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| Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T.
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| Front Mol Neurosci 11:247. doi: 10.3389/fnmol.2018.00247. eCollection 2018.
2018
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| 2 | NDP, WNT7A, WNT7B
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| Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance.
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| Wang Y, Cho C, Williams J, Smallwood PM, Zhang C, Junge HJ, Nathans J.
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| Proc Natl Acad Sci U S A 115(50):E11827-E11836. doi: 10.1073/pnas.1813217115. Epub 2018 Nov 26.
2018
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| 3 | WNT7A
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| High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
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| Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K.
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| Sci Rep 8(1):15792. doi: 10.1038/s41598-018-34094-3.
2018
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| 4 | WNT7A
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| Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines.
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| Wallace J, Lutgen V, Avasarala S, St Croix B, Winn RA, Al-Harthi L.
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| Immunology 153(2):203-213. doi: 10.1111/imm.12830. Epub 2017 Oct 12.
2018
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| 5 | LPHAS, WNT7A
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| Al-Awadi-Raas-Rothschild syndrome with dental anomalies and a novel WNT7A mutation.
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| Kantaputra PN, Kapoor S, Verma P, Kaewgahya M, Kawasaki K, Ohazama A, Ketudat Cairns JR.
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| Eur J Med Genet 60(12):695-700. doi: 10.1016/j.ejmg.2017.09.005. Epub 2017 Sep 14.
2017
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| 6 | FACFB, WNT7A
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| Santos syndrome is caused by mutation in the WNT7A gene.
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| Alves LU, Santos S, Musso CM, Ezquina SA, Opitz JM, Kok F, Otto PA, Mingroni-Netto RC.
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| J Hum Genet 62(12):1073-1078. doi: 10.1038/jhg.2017.86. Epub 2017 Aug 31.
2017
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| 7 | GPR124, RECK, WNT7A, WNT7B
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| Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.
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| Cho C, Smallwood PM, Nathans J.
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| Neuron 95(5):1056-1073.e5. doi: 10.1016/j.neuron.2017.07.031. Epub 2017 Aug 10.
2017
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| 8 | FACFB, WNT7A
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| Santos syndrome is caused by mutation in the WNT7A gene.
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| Alves LU, Santos S, Musso CM, Ezquina SA, Opitz JM, Kok F, Otto PA, Mingroni-Netto RC.
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| J Hum Genet 62(12):1073-1078. doi: 10.1038/jhg.2017.86. Epub 2017 Aug 31.
2017
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| 9 | WNT5A, WNT7A
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| Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs.
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| Farah O, Biechele S, Rossant J, Dufort D.
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| Dev Biol 422(1):58-69. doi: 10.1016/j.ydbio.2016.11.023. Epub 2016 Dec 10.
2017
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| 10 | LPHAS, WNT7A
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| A novel missense mutation, p.(R102W) in WNT7A causes Al-Awadi Raas-Rothschild syndrome in a fetus.
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| Mutlu MB, Cetinkaya A, Koc N, Ceylaner G, Erguner B, Aydın H, Karaman S, Demirci O, Goksu K, Karaman A.
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| Eur J Med Genet 59(11):604-606. doi: 10.1016/j.ejmg.2016.09.009. Epub 2016 Sep 13.
2016
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| 11 | DCN, ITGB1, WNT7A
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| Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin.
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| Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C.
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| Nat Commun 7:10354. doi: 10.1038/ncomms10354.
2016
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| 12 | WNT7A
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| Overexpression of Wnt7α protein predicts poor survival in patients with colorectal carcinoma.
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| Wang Y, Wei J, Zhang S, Li G, Zhang T, Yu X, Chen H, Liu M.
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| Tumour Biol 36(11):8781-7. doi: 10.1007/s13277-015-3633-6. Epub 2015 Jun 9.
2015
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| 13 | WNT7A
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| Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer.
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| Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn RA.
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| Oncogene 34(42):5317-28. doi: 10.1038/onc.2015.2. Epub 2015 Mar 2. Erratum in: Oncogene. 2015 Oct 16;34(42):5406.
2015
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| 14 | PAX6, WNT7A
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| WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis.
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| Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, Cai H, Luo J, Zhang M, Zhang M, Yang Y, Li G, Li H, Jiang W, Yeh E, Lin J, Pei M, Zhu J, Cao G, Zhang L, Yu B, Chen S, Fu XD, Liu Y, Zhang K.
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| Nature 511(7509):358-61. doi: 10.1038/nature13465. Epub 2014 Jul 2.
2014
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| 15 | WNT7A
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| Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.
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| Fernando CV, Kele J, Bye CR, Niclis JC, Alsanie W, Blakely BD, Stenman J, Turner BJ, Parish CL.
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| Stem Cells Dev 23(17):1991-2003. doi: 10.1089/scd.2014.0166. Epub 2014 Jun 30.
2014
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| 16 | FN1, WNT7a
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| Fibronectin regulates Wnt7a signaling and satellite cell expansion.
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| Bentzinger CF, Wang YX, von Maltzahn J, Soleimani VD, Yin H, Rudnicki MA.
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| Cell Stem Cell 12(1):75-87. doi: 10.1016/j.stem.2012.09.015.
2013
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| 17 | WNT7A
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| A truncated Wnt7a retains full biological activity in skeletal muscle.
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| von Maltzahn J, Zinoviev R, Chang NC, Bentzinger CF, Rudnicki MA.
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| Nat Commun 4:2869. doi: 10.1038/ncomms3869.
2013
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| 18 | WNT7A
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| Wnt7a regulates multiple steps of neurogenesis.
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| Qu Q, Sun G, Murai K, Ye P, Li W, Asuelime G, Cheung YT, Shi Y.
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| Mol Cell Biol 33(13):2551-9. doi: 10.1128/MCB.00325-13. Epub 2013 Apr 29.
2013
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| 19 | WNT7A
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| WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway.
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| Yoshioka S, King ML, Ran S, Okuda H, MacLean JA 2nd, McAsey ME, Sugino N, Brard L, Watabe K, Hayashi K.
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| Mol Cancer Res 10(3):469-82. doi: 10.1158/1541-7786.MCR-11-0177. Epub 2012 Jan 9.
2012
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| 20 | DMD, WNT7A
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| Wnt7a treatment ameliorates muscular dystrophy.
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| von Maltzahn J, Renaud JM, Parise G, Rudnicki MA.
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| Proc Natl Acad Sci U S A 109(50):20614-9. doi: 10.1073/pnas.1215765109. Epub 2012 Nov 26.
2012
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| 21 | DVL1, WNT7A
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| Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca²⁺/Calmodulin-dependent protein kinase II.
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| Ciani L, Boyle KA, Dickins E, Sahores M, Anane D, Lopes DM, Gibb AJ, Salinas PC.
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| Proc Natl Acad Sci U S A 108(26):10732-7. Epub 2011 Jun 13.
2011
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| 22 | APC, CTNNB1, DISC1, DLG4, FZD1, GSK3B, NEUROD1, PRICKLE1, SFRP1, SYN1, WNT1, WNT3, WNT3A, WNT5A, WNT7A
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| Emerging roles of Wnts in the adult nervous system.
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| Inestrosa NC, Arenas E.
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| Nat Rev Neurosci. 11(2):77-86. 2010
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| 23 | FZD5, WNT7A
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| Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis.
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| Sahores M, Gibb A, Salinas PC.
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| Development 137(13):2215-25. doi: 10.1242/dev.046722.
2010
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| 24 | WNT7A, FZD5
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| Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP.
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| Carmon KS, Loose DS.
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| Biochem Biophys Res Commun 368(2):285-91. Epub 2008 Jan 28. 2008
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| 25 | WNT7A, WNT7B
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| Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature.
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| Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, McMahon J, McMahon AP.
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| Science 322(5905):1247-50.PMID: 19023080 2008
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| 26 | WNT7A, LPHAS
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| Al-Awadi/Raas-Rothschild syndrome: two new cases and review.
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| Lonardo F, Sabba G, Luquetti DV, Monica MD, Scarano G.
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| Am J Med Genet A 143(24):3169-74. 2007
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| 27 | WNT7A
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| Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons.
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| Cerpa W, Godoy JA, Alfaro I, Farķas GG, Metcalfe MJ, Fuentealba R, Bonansco C, Inestrosa NC.
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| J Biol Chem. 283(9):5918-27. 2007
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| 28 | LPHAS, WNT7A
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| Mutations in WNT7A cause a range of limb malformations, including Fuhrmann Syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome.
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| Woods CG, Stricker S, Seemann P, Stern R, Cox J, Sherridan E, Roberts E, Springell K, Scott S, Karbani G, Sharif SM, Toomes C, Bond J, Kumar D, Al-Gazali L, Mundlos S.
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| Am J Hum Genet 79(2):402-8. Epub 2006 Jun 23. 2006
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| 29 | WNT7A
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| Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release.
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| Ahmad-Annuar A, Ciani L, Simeonidis I, Herreros J, Fredj NB, Rosso SB, Hall A, Brickley S, Salinas PC.
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| J Cell Biol. 174(1):127-39. 2006
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| 30 | WNT7A
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| Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.
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| Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE.
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| J Biol Chem. 280(20):19625-34 2005
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| 31 | WNT7A
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| WNTs in the vertebrate nervous system: from patterning to neuronal connectivity.
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| Ciani L, Salinas PC.
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| Nat Rev Neurosci. 6(5):351-62. 2005
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| 32 | WNT7A
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| Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms.
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| Hwang SG, Ryu JH, Kim IC, Jho EH, Jung HC, Kim K, Kim SJ, Chun JS.
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| J Biol Chem 279(25):26597-604. Epub 2004 Apr 13. 2004
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| 33 | WNT7A
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| The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells.
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| Hirabayashi Y, Itoh Y, Tabata H, Nakajima K, Akiyama T, Masuyama N, Gotoh Y.
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| Development. 131(12):2791-801. 2004
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| 34 | CDH1, WNT7A
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| WNT7a induces E-cadherin in lung cancer cells.
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| Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, Wilder E, Rustgi A, Kitajewski J, Gabrielson E, Bremnes R, Franklin W, Drabkin HA.
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| Proc Natl Acad Sci U S A 100(18):10429-34. Epub 2003 Aug 22. 2003
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| 35 | WNT7A
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| Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.
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| Caricasole A, Ferraro T, Iacovelli L, Barletta E, Caruso A, Melchiorri D, Terstappen GC, Nicoletti F.
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| J Biol Chem. 278(39):37024-31. 2003
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| 36 | WNT7A, WNT7B
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| Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer.
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| Kirikoshi H, Katoh M.
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| Int J Oncol 21(4):895-900. 2002
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| 37 | WNT7A
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| Decreased expression of Wnt7a mRNA is inversely associated with the expression of estrogen receptor-alpha in human uterine leiomyoma.
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| Li S, Chiang TC, Davis GR, Williams RM, Wilson VP, McLachlan JA.
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| J Clin Endocrinol Metab. 86(1):454-7. 2001
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| 38 | WNT7A
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| Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a.
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| Parr BA, McMahon AP.
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| Nature 395(6703):707-10. 1998
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| 39 | WNT7A
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| Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25.
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| Bui TD, Lako M, Lejeune S, Curtis AR, Strachan T, Lindsay S, Harris AL.
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| Gene 189(1):25-9. 1997
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| 40 | WNT7A
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| Isolation, characterization and chromosomal assignment of the human WNT7A gene.
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| Ikegawa S, et al.
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| Cytogenet Cell Genet 74 : 149-152. 1996
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| 41 | WNT7A, LMX1A
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| Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb.
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| Riddle RD, et al.
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| Cell 83(4):631-40. 1995
|