1 | NEDD4L, SLC12A3, WNK3
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| WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter.
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| Lagnaz D, Arroyo JP, Chávez-Canales M, Vázquez N, Rizzo F, Spirlí A, Debonneville A, Staub O, Gamba G.
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| Am J Physiol Renal Physiol 307(3):F275-86. doi: 10.1152/ajprenal.00574.2013. Epub 2014 Jun 11.
2014
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2 | LINGO1, WNK3
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| LINGO-1 receptor promotes neuronal apoptosis by inhibiting WNK3 kinase activity.
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| Zhang Z, Xu X, Xiang Z, Yu Z, Feng J, He C.
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| J Biol Chem 288(17):12152-60. doi: 10.1074/jbc.M112.447771. Epub 2013 Mar 12.
2013
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3 | RBFOX1, WNK3
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| Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
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| Lee AY, Chen W, Stippec S, Self J, Yang F, Ding X, Chen S, Juang YC, Cobb MH.
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| Proc Natl Acad Sci U S A 109(42):16841-6. doi: 10.1073/pnas.1215406109. Epub 2012 Oct 1.
2012
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4 | TRPV5, WNK1, WNK2, WNK3, WNK4
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| WNK4 kinase stimulates caveola-mediated endocytosis of TRPV5 amplifying the dynamic range of regulation of the channel by protein kinase C.
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| Cha SK, Huang CL.
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| J Biol Chem 285(9):6604-11. Epub 2010 Jan 8.PMID: 20061383 2010
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5 | SLC12A4, SLC12A5, SLC12A6, SLC12A7, WNK3
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| Renal and brain isoforms of WNK3 have opposite effects on NCCT expression.
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| Glover M, Zuber AM, O'Shaughnessy KM.
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| J Am Soc Nephrol 20(6):1314-22. Epub 2009 May 21.
2009
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6 | STK39, WNK3, SLC12A1
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| Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
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| Ponce-Coria J, San-Cristobal P, Kahle KT, Vazquez N, Pacheco-Alvarez D, de Los Heros P, Ju‡rez P, Mu–oz E, Michel G, Bobadilla NA, Gimenez I, Lifton RP, Hebert SC, Gamba G.
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| Proc Natl Acad Sci U S A 105(24):8458-63. Epub 2008 Jun 11. 2008
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7 | OXSR1, STK39, WNK1, WNK2, WNK3, WNK4
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| The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway.
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| Richardson C, Alessi DR.
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| J Cell Sci 121(Pt 20):3293-304. Review.
2008
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8 | TRPV5, TRPV6, WNK3
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| WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway.
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| Zhang W, Na T, Peng JB.
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| Am J Physiol Renal Physiol 295(5):F1472-84. Epub 2008 Sep 3.
2008
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9 | WNK3, WNK4
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| WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter.
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| San-Cristobal P, Ponce-Coria J, Vázquez N, Bobadilla NA, Gamba G.
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| Am J Physiol Renal Physiol 295(4):F1199-206. Epub 2008 Aug 13.
2008
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10 | SLC12A3, WNK1, WNK3, WNK4
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| The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
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| Yang CL, Zhu X, Ellison DH.
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| J Clin Invest 117(11):3403-11. 2007
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11 | WNK3, SLC12A1, SLC12A3
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| WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.
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| Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP.
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| Proc Natl Acad Sci U S A 102(46):16777-82. Epub 2005 Nov 7. 2005
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12 | WNK3
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| WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.
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| Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP.
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| Proc Natl Acad Sci U S A 102(46):16783-8. Epub 2005 Nov 7. 2005
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13 | WNK2, WNK3
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| Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).
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| Holden S, Cox J, Raymond FL.
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| Gene 335:109-19. 2004
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14 | WNK3
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| Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).
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| Holden S, Cox J, Raymond FL.
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| Gene 335:109-19.
2004
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15 | HNRNPL, WNK2, WNK3
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| Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
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| Ito M, Shichijo S, Tsuda N, Ochi M, Harashima N, Saito N, Itoh K.
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| Cancer Res 61(5):2038-46. 2001
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16 | WNK1, WNK2, WNK3, WNK4
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| WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.
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| Verissimo F, Jordan P.
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| Oncogene 20(39):5562-9. 2001
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17 | ANKRD36B, BCOR, BEND3, CACHD1, CHD8, CNNM4, DDX55, DHTKD1, EIF2C4, EPB41L5, EPG5, FAM160B1, GBA2, GPAM, GPR107, HERC4, KIAA1586, KIAA1609, KIF16B, MAGEE1, MAGI3, MED12L, MED12L, METTL14, MIER1, MOV10, NCKAP5L, NCOA5, PCDHB16, RNF213, SEMA4G, SFMBT2, SMURF1, TNRC6C, TRPM3, USP37, VAT1L, WDFY4, WDR19, WNK3, ZBTB26, ZNF532, ZPR1 ZNF319, ZSWIM5, ZSWIM6
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| Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O.
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| DNA Res 7(4):273-81. 2000
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