| 1 | CUL3, KLHL3, PHA2B, PHA2C, PHA2D, PHA2E, WNK2, WNK4
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| Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.
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| Yoshizaki Y, Mori Y, Tsuzaki Y, Mori T, Nomura N, Wakabayashi M, Takahashi D, Zeniya M, Kikuchi E, Araki Y, Ando F, Isobe K, Nishida H, Ohta A, Susa K, Inoue Y, Chiga M, Rai T, Sasaki S, Uchida S, Sohara E.
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| Biochem Biophys Res Commun 467(2):229-34. doi: 10.1016/j.bbrc.2015.09.184. Epub 2015 Oct 3. 2015
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| 2 | WNK2
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| Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness.
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| Moniz S, Martinho O, Pinto F, Sousa B, Loureiro C, Oliveira MJ, Moita LF, Honavar M, Pinheiro C, Pires M, Lopes JM, Jones C, Costello JF, Paredes J, Reis RM, Jordan P.
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| Hum Mol Genet 22(1):84-95. doi: 10.1093/hmg/dds405. Epub 2012 Oct 3.
2013
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| 3 | SLC12A2, STK39, WNK2
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| WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.
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| Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP.
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| J Biol Chem 286(34):30171-80. Epub 2011 Jul 6.
2011
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| 4 | TRPV5, WNK1, WNK2, WNK3, WNK4
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| WNK4 kinase stimulates caveola-mediated endocytosis of TRPV5 amplifying the dynamic range of regulation of the channel by protein kinase C.
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| Cha SK, Huang CL.
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| J Biol Chem 285(9):6604-11. Epub 2010 Jan 8.PMID: 20061383 2010
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| 5 | WNK2
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| Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.
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| Jun P, Hong C, Lal A, Wong JM, McDermott MW, Bollen AW, Plass C, Held WA, Smiraglia DJ, Costello JF.
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| Neuro Oncol 11(4):414-22. Epub 2008 Nov 11.
2009
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| 6 | WNK2
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| WNK2 modulates MEK1 activity through the Rho GTPase pathway.
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| Moniz S, Matos P, Jordan P.
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| Cell Signal 20(10):1762-8. Epub 2008 Jun 14.
2008
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| 7 | OXSR1, STK39, WNK1, WNK2, WNK3, WNK4
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| The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway.
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| Richardson C, Alessi DR.
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| J Cell Sci 121(Pt 20):3293-304. Review.
2008
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| 8 | WNK2
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| Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2.
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| Moniz S, Veríssimo F, Matos P, Brazão R, Silva E, Kotelevets L, Chastre E, Gespach C, Jordan P.
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| Oncogene 26(41):6071-81. Epub 2007 Jul 30. Erratum in: Oncogene. 2008 Jan 3;27(1):155. Kotevelets, L [corrected to Kotelevets, L].
2007
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| 9 | WNK2, WNK3
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| Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).
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| Holden S, Cox J, Raymond FL.
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| Gene 335:109-19. 2004
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| 10 | HNRNPL, WNK2, WNK3
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| Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
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| Ito M, Shichijo S, Tsuda N, Ochi M, Harashima N, Saito N, Itoh K.
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| Cancer Res 61(5):2038-46. 2001
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| 11 | WNK1, WNK2, WNK3, WNK4
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| WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.
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| Verissimo F, Jordan P.
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| Oncogene 20(39):5562-9. 2001
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| 12 | WNK1, WNK2
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| WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II.
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| Xu B, English JM, Wilsbacher JL, Stippec S, Goldsmith EJ, Cobb MH.
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| J Biol Chem 275(22):16795-801. 2000
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| 13 | ACAP3, AMBRA1, CMIP, CNTNAP3, CNTNAP4, CPEB4, DAB2IP, DDHD1, DISP2, EEPD1, EXOC4, FAM40A, HELZ2, ITPRIP, KIAA1683, KIAA1712, KIAA1715, KIAA1737, KIAA1751, KIAA1755, KIF21A, MTMR12, PHACTR1, PHF21A, PRDM16, RAPH1, RHOXF1, SEMA4B, SEMA4C, SET7, SH3BP5L, SPHKAP, SSH2, TET1, TEX2, TNKS1BP1, UBE2O, UNC13A, UNK, WNK2, ZCCHC2, ZFHX2, ZNF407, ZNF436
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| Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O.
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| DNA Res 7(6):347-55. 2000
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| 14 | CWC27, HSPH1, MBD2, SDCCAG1, SDCCAG3, SDCCAG8, STARD10, STUB1, TSHZ1, USH1C, UTP14A, WNK2
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| Characterization of human colon cancer antigens recognized by autologous antibodies.
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| Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, TureciO, Sahin U, Pfreundschuh M, Old LJ.
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| Int J Cancer 76(5):652-8. 1998
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