Citations for
1WDR45, WDR45B, WIPI1, WIPI2
WIPI proteins: Biological functions and related syndromes.
Almannai M, Marafi D, El-Hattab AW.
Front Mol Neurosci. Sep 9;15:1011918. doi: 10.3389/fnmol.2022.1011918. 2022
2VCP, WIPI2
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
Lu G, Tan HWS, Schmauck-Medina T, Wang L, Chen J, Cho YL, Chen K, Zhang JZ, He W, Wu Y, Xia D, Zhou J, Fang EF, Fang L, Liu W, Shen HM.
Autophagy. Dec;18(12):2865-2879. doi: 10.1080/15548627.2022.2052461. Epub 2022 Apr 7. 2022
3IDSSA, WIPI2
Homozygous missense WIPI2 variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course. . 2021 PMID:
Maroofian R, Gubas A, Kaiyrzhanov R, Scala M, Hundallah K, Severino M, Abdel-Hamid MS, Rosenfeld JA, Ebrahimi-Fakhari D, Ali Z, Rahim F, Houlden H, Tooze SA, Alsaleh NS, Zaki MS.
Brain Commun Sep 3;3(3):fcab183. doi: 10.1093/braincomms/fcab183. 2021
4ATG16L1, WIPI2
Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.
Strong LM, Chang C, Riley JF, Boecker CA, Flower TG, Buffalo CZ, Ren X, Stavoe AK, Holzbaur EL, Hurley JH.
Elife. Sep 10;10:e70372. doi: 10.7554/eLife.70372. 2021
5WIPI2
Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. 2020 PMID:
Stavoe AKH, Holzbaur ELF
Autophagy. Feb;16(2):371-372. doi: 10.1080/15548627.2019.1695401. Epub 2019 Dec 3. 2020
6WDR45, WDR45B, WIPI1, WIPI2
Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins
Liang R, Ren J, Zhang Y, Feng W.
J Mol Biol. Mar 29;431(7):1494-1505. doi: 10.1016/j.jmb.2019.02.019. Epub 2019 Feb 22. 2019
7IDSSA, WIPI2
A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities
Jelani M, Dooley HC, Gubas A, Mohamoud HSA, Khan MTM, Ali Z, Kang C, Rahim F, Jan A, Vadgama N, Khan MI, Al-Aama JY, Khan A, Tooze SA, Nasir J.
Brain. May 1;142(5):1242-1254. doi: 10.1093/brain/awz075. 2019
8CRTC1, HUWE1, WIPI2
MTORC1 regulates autophagic membrane growth by targeting WIPI2
Wan W, Liu W.
Autophagy. Apr;15(4):742-743. doi: 10.1080/15548627.2019.1569949. Epub 2019 Jan 22. 2019
9WDR45B, WIPI1, WIPI2
Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins
Liang R, Ren J, Zhang Y, Feng W.
J Mol Biol. Mar 29;431(7):1494-1505. doi: 10.1016/j.jmb.2019.02.019. Epub 2019 Feb 22. 2019
10WDR45, WDR45B, WIPI1, WIPI2
Function of human WIPI proteins in autophagosomal rejuvenation of endomembranes? 2015 PMID:
Müller AJ, Proikas-Cezanne T.
FEBS Lett. Jun 22;589(14):1546-51. doi: 10.1016/j.febslet.2015.05.008. Epub 2015 May 14. 2015
11WIPI1, WIPI2
Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes.
Proikas-Cezanne T, Robenek H.
J Cell Mol Med. Sep;15(9):2007-10. doi: 10.1111/j.1582-4934.2011.01339.x. 2011
12WIPI2
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S.
Anal Chem 81(11):4493-501. 2009
13WDR45L, WDR45, WIPI1, WIPI2
WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.
Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A.
Oncogene 23(58):9314-25. 2004
14WDR45, WDR45L, WIPI1, WIPI2
PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.
Jeffries TR, Dove SK, Michell RH, Parker PJ.
Mol Biol Cell 15(6):2652-63. Epub 2004 Mar 12. 2004