1 | WDR45, WDR45B, WIPI1, WIPI2
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| WIPI proteins: Biological functions and related syndromes.
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| Almannai M, Marafi D, El-Hattab AW.
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| Front Mol Neurosci. Sep 9;15:1011918. doi: 10.3389/fnmol.2022.1011918. 2022
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2 | VCP, WIPI2
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| WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
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| Lu G, Tan HWS, Schmauck-Medina T, Wang L, Chen J, Cho YL, Chen K, Zhang JZ, He W, Wu Y, Xia D, Zhou J, Fang EF, Fang L, Liu W, Shen HM.
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| Autophagy. Dec;18(12):2865-2879. doi: 10.1080/15548627.2022.2052461. Epub 2022 Apr 7. 2022
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3 | IDSSA, WIPI2
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| Homozygous missense WIPI2 variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course. . 2021 PMID:
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| Maroofian R, Gubas A, Kaiyrzhanov R, Scala M, Hundallah K, Severino M, Abdel-Hamid MS, Rosenfeld JA, Ebrahimi-Fakhari D, Ali Z, Rahim F, Houlden H, Tooze SA, Alsaleh NS, Zaki MS.
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| Brain Commun Sep 3;3(3):fcab183. doi: 10.1093/braincomms/fcab183. 2021
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4 | ATG16L1, WIPI2
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| Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.
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| Strong LM, Chang C, Riley JF, Boecker CA, Flower TG, Buffalo CZ, Ren X, Stavoe AK, Holzbaur EL, Hurley JH.
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| Elife. Sep 10;10:e70372. doi: 10.7554/eLife.70372. 2021
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5 | WIPI2
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| Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. 2020 PMID:
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| Stavoe AKH, Holzbaur ELF
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| Autophagy. Feb;16(2):371-372. doi: 10.1080/15548627.2019.1695401. Epub 2019 Dec 3. 2020
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6 | WDR45, WDR45B, WIPI1, WIPI2
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| Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins
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| Liang R, Ren J, Zhang Y, Feng W.
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| J Mol Biol. Mar 29;431(7):1494-1505. doi: 10.1016/j.jmb.2019.02.019. Epub 2019 Feb 22. 2019
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7 | IDSSA, WIPI2
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| A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities
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| Jelani M, Dooley HC, Gubas A, Mohamoud HSA, Khan MTM, Ali Z, Kang C, Rahim F, Jan A, Vadgama N, Khan MI, Al-Aama JY, Khan A, Tooze SA, Nasir J.
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| Brain. May 1;142(5):1242-1254. doi: 10.1093/brain/awz075. 2019
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8 | CRTC1, HUWE1, WIPI2
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| MTORC1 regulates autophagic membrane growth by targeting WIPI2
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| Wan W, Liu W.
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| Autophagy. Apr;15(4):742-743. doi: 10.1080/15548627.2019.1569949. Epub 2019 Jan 22. 2019
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9 | WDR45B, WIPI1, WIPI2
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| Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins
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| Liang R, Ren J, Zhang Y, Feng W.
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| J Mol Biol. Mar 29;431(7):1494-1505. doi: 10.1016/j.jmb.2019.02.019. Epub 2019 Feb 22. 2019
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10 | WDR45, WDR45B, WIPI1, WIPI2
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| Function of human WIPI proteins in autophagosomal rejuvenation of endomembranes? 2015 PMID:
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| Müller AJ, Proikas-Cezanne T.
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| FEBS Lett. Jun 22;589(14):1546-51. doi: 10.1016/j.febslet.2015.05.008. Epub 2015 May 14. 2015
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11 | WIPI1, WIPI2
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| Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes.
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| Proikas-Cezanne T, Robenek H.
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| J Cell Mol Med. Sep;15(9):2007-10. doi: 10.1111/j.1582-4934.2011.01339.x. 2011
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12 | WIPI2
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| Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
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| Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S.
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| Anal Chem 81(11):4493-501.
2009
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13 | WDR45L, WDR45, WIPI1, WIPI2
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| WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.
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| Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A.
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| Oncogene 23(58):9314-25. 2004
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14 | WDR45, WDR45L, WIPI1, WIPI2
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| PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.
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| Jeffries TR, Dove SK, Michell RH, Parker PJ.
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| Mol Biol Cell 15(6):2652-63. Epub 2004 Mar 12. 2004
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