Citations for
Human epididymis protein 4 (HE4) plays a key role in ovarian cancer cell adhesion and motility.
Lu R, Sun X, Xiao R, Zhou L, Gao X, Guo L.
Biochem Biophys Res Commun 419(2):274-80. doi: 10.1016/j.bbrc.2012.02.008. Epub 2012 Feb 10. 2012
HE4 expression can be associated with lymph node metastases and disease-free survival in breast cancer.
Kamei M, Yamashita S, Tokuishi K, Hashioto T, Moroga T, Suehiro S, Ono K, Miyawaki M, Takeno S, Yamamoto S, Kawahara K.
Anticancer Res 30(11):4779-83. 2010
Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms.
Hellstrom I, Heagerty PJ, Swisher EM, Liu P, Jaffar J, Agnew K, Hellstrom KE.
Cancer Lett 296(1):43-8. Epub 2010 Apr 8. 2010
Human epididymis protein 4 is a biomarker for transitional cell carcinoma in the urinary system.
Xi Z, LinLin M, Ye T.
J Clin Lab Anal 23(6):357-61. 2009
HE4 as a biomarker for ovarian and endometrial cancer management.
Li J, Dowdy S, Tipton T, Podratz K, Lu WG, Xie X, Jiang SW.
Expert Rev Mol Diagn 9(6):555-66. Review. 2009
In silico study of whey-acidic-protein domain containing oral protease inhibitors.
Idoji Y, Watanabe Y, Yamashita A, Yamanishi K, Nishiguchi S, Shimada K, Yasunaga T, Yamanishi H.
Int J Mol Med 21(4):461-8. 2008
WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung.
Bingle L, Cross SS, High AS, Wallace WA, Rassl D, Yuan G, Hellstrom I, Campos MA, Bingle CD.
Respir Res 7:61. 2006
Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas.
Drapkin R, von Horsten HH, Lin Y, Mok SC, Crum CP, Welch WR, Hecht JL.
Cancer Res 65(6):2162-9. 2005
The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.
Bingle L, Singleton V, Bingle CD.
Oncogene 21(17):2768-73. 2002
Molecular characterization of epididymal proteins.
Kirchhoff C.
Rev Reprod 3(2):86-95. Review. 1998
A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors.
Kirchhoff C, Habben I, Ivell R, Krull N.
Biol Reprod 45(2):350-7. 1991