Citations for
1WDR77
E2F and GATA switches turn off WD repeat domain 77 expression in differentiating cells.
Yu M, Wang U, Wang Z.
Biochem J 473(15):2331-43. doi: 10.1042/BCJ20160130. Epub 2016 Jun 7. 2016
2IVL, PRKCD, PRKCD, WDR77
MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
Saha K, Adhikary G, Eckert RL.
J Invest Dermatol 136(1):214-24. doi: 10.1038/JID.2015.400. 2016
3PRMT5, WDR77
Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
Burgos ES, Wilczek C, Onikubo T, Bonanno JB, Jansong J, Reimer U, Shechter D.
J Biol Chem 290(15):9674-89. doi: 10.1074/jbc.M115.636894. Epub 2015 Feb 24. 2015
4WDR77
P44/WDR77 restricts the sensitivity of proliferating cells to TGFβ signaling.
Yi P, Gao S, Gu Z, Huang T, Wang Z.
Biochem Biophys Res Commun 450(1):409-15. doi: 10.1016/j.bbrc.2014.05.125. Epub 2014 Jun 2. 2014
5WDR77
Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.
Wei TY, Hsia JY, Chiu SC, Su LJ, Juan CC, Lee YC, Chen JM, Chou HY, Huang JY, Huang HM, Yu CT.
Cell Signal 26(12):2940-50. doi: 10.1016/j.cellsig.2014.09.014. Epub 2014 Sep 30. 2014
6PRKG1, WDR77
cGMP-dependent protein kinase Iβ interacts with p44/WDR77 to regulate androgen receptor-driven gene expression.
Zhou L, Hosohata K, Gao S, Gu Z, Wang Z.
PLoS One 8(6):e63119. doi: 10.1371/journal.pone.0063119. Print 2014. 2013
7AR, WDR77
Functional domains of androgen receptor coactivator p44/Mep50/WDR77and its interaction with Smad1.
Li Y, Tian L, Ligr M, Daniels G, Peng Y, Wu X, Singh M, Wei J, Shao Y, Lepor H, Xu R, Chang Z, Wang Z, Lee P.
PLoS One 8(5):e64663. doi: 10.1371/journal.pone.0064663. Print 2013. 2013
8CDK19, CDK8, PRMT5, WDR77
Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.
Tsutsui T, Fukasawa R, Shinmyouzu K, Nakagawa R, Tobe K, Tanaka A, Ohkuma Y.
J Biol Chem 288(29):20955-65. doi: 10.1074/jbc.M113.486746. Epub 2013 Jun 9. 2013
9WDR77
Subcellular localization of p44/WDR77 determines proliferation and differentiation of prostate epithelial cells.
Gao S, Wang Z.
PLoS One 7(11):e49173. doi: 10.1371/journal.pone.0049173. Epub 2012 Nov 8. 2012
10WDR77
Loss of the androgen receptor cofactor p44/WDR77 induces astrogliosis.
Vincent B, Wu H, Gao S, Wang Z.
Mol Cell Biol 32(17):3500-12. doi: 10.1128/MCB.00298-12. Epub 2012 Jul 2. 2012
11PRMT5, WDR77
Crystal structure of the human PRMT5:MEP50 complex.
Antonysamy S, Bonday Z, Campbell RM, Doyle B, Druzina Z, Gheyi T, Han B, Jungheim LN, Qian Y, Rauch C, Russell M, Sauder JM, Wasserman SR, Weichert K, Willard FS, Zhang A, Emtage S.
Proc Natl Acad Sci U S A 109(44):17960-5. doi: 10.1073/pnas.1209814109. Epub 2012 Oct 15. 2012
12CLNS1A, PRMT5, RIOK1, WDR77
RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.
Guderian G, Peter C, Wiesner J, Sickmann A, Schulze-Osthoff K, Fischer U, Grimmler M.
J Biol Chem 286(3):1976-86. Epub 2010 Nov 16. 2011
13PRMT5, WDR77
Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.
Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, Hajkova P, Surani MA.
Genes Dev 24(24):2772-7. 2010
14WDR77
Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer.
Peng Y, Chen F, Melamed J, Chiriboga L, Wei J, Kong X, McLeod M, Li Y, Li CX, Feng A, Garabedian MJ, Wang Z, Roeder RG, Lee P.
Proc Natl Acad Sci U S A 105(13):5236-41. Epub 2008 Mar 20. 2008
15PRMT5, WDR77
The expression and function of androgen receptor coactivator p44 and protein arginine methyltransferase 5 in the developing testis and testicular tumors.
Liang JJ, Wang Z, Chiriboga L, Greco MA, Shapiro E, Huang H, Yang XJ, Huang J, Peng Y, Melamed J, Garabedian MJ, Lee P.
J Urol 177(5):1918-22. 2007
16WDR77, PRMT5, SUZ12
Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro.
Furuno K, Masatsugu T, Sonoda M, Sasazuki T, Yamamoto K.
Biochem Biophys Res Commun 345(3):1051-8. Epub 2006 May 11. 2006
17MBD2, MBD3, PRMT5, WDR77
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.
Le Guezennec X, Vermeulen M, Brinkman AB, Hoeijmakers WA, Cohen A, Lasonder E, Stunnenberg HG.
Mol Cell Biol 26(3):843-51. 2006
18WDR77
Roles of the androgen receptor cofactor p44 in the growth of prostate epithelial cells.
Zhou L, Wu H, Lee P, Wang Z.
J Mol Endocrinol 37(2):283-300. 2006
19WDR77, POLR2B, NDRG2, STK38, PRMT5, CTDP1, ERH, FCP1
Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation.
Amente S, Napolitano G, Licciardo P, Monti M, Pucci P, Lania L, Majello B.
FEBS Lett 579(3):683-9. 2005
20PRMT5, WDR77
A novel WD repeat protein component of the methylosome binds Sm proteins.
Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G.
J Biol Chem 277(10):8243-7. Epub 2001 Dec 26. 2002
21ABCB6, ADCK2, ANAPC7, ANKRD46, ASPHD1, AVPI1, AZIN1, BRINP2, C12orf24, C14orf79, C17orf90, C17orf91, C5orf15, C9orf127, C9orf25, C9orf82, CNIH3, COG3, COG7, CREB3L1, CSRNP2, DHX29, DHX57, DLAT, EIF2B2, ERI3, FAM13C1, FAM35A, FAM54B, FLAD1, GHITM, GRIP2, GRPEL1, HMGCLL1, IP6K2, IP6K2, ITGB1BP1, KCMF1, KIFC2, LRP10, MDM1, MFN1, NAPG, NCALD, NECAB2, NIPAL4, NPTN, NTNG2, PASK, PCDHB10, PDIA6, PHPT1, PI4K2A, PNPLA2, POGK, PTOV1, RNF13, RNF41, SAC3D1, SDCBP2, SELT, SLC38A6, SLC39A3, SMURF1, SPRED2, SUCLG2, TMCO1, TMEM183A, TP53I11, TRPC4AP, TSC22D3, TUBB, TXNDC12, UTP18, WDR40A, WDR77, WSB2, ZMIZ1
Large-scale concatenation cDNA sequencing.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY,Wentland MA, Lennon G, Gibbs RA.
Genome Res 7(4):353-8. 1997
22ADCK2, ANAPC7, ARHGAP22, AVPI1, AZIN1, C12orf24, C14orf79, C5orf15, C9orf25, CNIH3, COG3, COG7, CREB3L1, DHX29, DHX57, DLAT, DLGAP3, EIF2B2, EXOC3, FAM13C1, FAM152B, FAM35A, FAM54B, FAM89B, FLAD1, GHITM, GRPEL1, HMGCLL1, IP6K2, IPO4, ITGB1BP1, KCMF1, KIFC2, LRP10, MDM1, MFN1, NAPG, NCALD, NECAB2, NPTN, NTNG2, PASK, PCDHB10, PHPT1, PI4K2A, PNPLA2, POGK, PTOV1, RNF41, SAC3D1, SDCBP2, SELT, SEMA6C, SLC38A6, SLC39A3, SMURF1, SPRED2, STX12, SUCLG2, TAX1BP3, TMEM183A, TP53I11, TRAPPC3, TRPC4AP, TSC22D3, TUBB, TXNDC12, UTP18, WDFY3, WDR40A, WDR77, WSB2, ZMIZ1, ZNF410, ZXDC
A double adaptor method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA.
Anal Biochem 236(1):107-13. 1996