| 1 | MHGDDDF, WBP11, WBP4
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| Bi-allelic loss-of-function variants in WBP4, encoding a spliceosome protein, result in a variable neurodevelopmental syndrome.
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| Engal E, Oja KT, Maroofian R, Geminder O, Le TL, Marzin P, Guimier A, Mor E, Zvi N, Elefant N, Zaki MS, Gleeson JG, Muru K, Pajusalu S, Wojcik MH, Pachat D, Elmaksoud MA, Chan Jeong W, Lee H, Bauer P, Zifarelli G, Houlden H, Daana M, Elpeleg O, Amiel J, Lyonnet S, Gordon CT, Harel T, Õunap K, Salton M, Mor-Shaked H.
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| Am J Hum Genet. Dec 7;110(12):2112-2119. doi: 10.1016/j.ajhg.2023.10.013. Epub 2023 Nov 13. 2023
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| 2 | SNRNP200, WBP4
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| FBP21's C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase
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| Sticht J, Bertazzon M, Henning LM, Licha JR, Abualrous ET, Freund C.
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| Biophys J. Feb 5;116(3):406-418. doi: 10.1016/j.bpj.2018.11.3123. Epub 2018 Nov 29. 2019
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| 3 | SNRNP200, WBP4
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| A new role for FBP21 as regulator of Brr2 helicase activity.
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| Henning LM, Santos KF, Sticht J, Jehle S, Lee CT, Wittwer M, Urlaub H, Stelzl U, Wahl MC, Freund C.
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| Nucleic Acids Res 45(13):7922-7937. doi: 10.1093/nar/gkx535.
2017
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| 4 | WBP4
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| Exploring monovalent and multivalent peptides for the inhibition of FBP21-tWW.
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| Henning LM, Bhatia S, Bertazzon M, Marczynke M, Seitz O, Volkmer R, Haag R, Freund C.
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| Beilstein J Org Chem 11:701-706. doi: 10.3762/bjoc.11.80. eCollection 2015.
2015
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| 5 | SF3B4, WBP4
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| Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome.
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| Klippel S, Wieczorek M, Schümann M, Krause E, Marg B, Seidel T, Meyer T, Knapp EW, Freund C.
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| J Biol Chem 286(44):38478-87. doi: 10.1074/jbc.M111.265710. Epub 2011 Sep 14.
2011
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| 6 | WBP11, WBP4
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| Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).
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| Huang X, Beullens M, Zhang J, Zhou Y, Nicolaescu E, Lesage B, Hu Q, Wu J, Bollen M, Shi Y.
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| J Biol Chem 284(37):25375-87. Epub 2009 Jul 10.PMID: 19592703 2009
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| 7 | DIAPH3, FNBP4, WBP4
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| Identification and characterization of human DIAPH3 gene in silico.
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| Katoh M, Katoh M.
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| Int J Mol Med 13(3):473-8. 2004
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| 8 | FNBP4, KHDRBS1, WBP4
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| Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
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| Bedford MT, Frankel A, Yaffe MB, Clarke S, Leder P, Richard S.
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| J Biol Chem 275(21):16030-6.PMID: 10748127 2000
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| 9 | FNBP4, WBP4
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| A novel pro-Arg motif recognized by WW domains.
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| Bedford MT, Sarbassova D, Xu J, Leder P, Yaffe MB.
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| J Biol Chem 275(14):10359-69.PMID: 10744724 2000
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| 10 | WBP4
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| WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.
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| Bedford MT, et al.
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| Proc Natl Acad Sci U S A 95(18):10602-7 1998
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| 11 | WBP4
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| WW domain-mediated interactions reveal a spliceosome-associated protein thatbinds a third class of proline-rich motif: the proline glycine andmethionine-rich motif.
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| Bedford MT, Reed R, Leder P.
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| Proc Natl Acad Sci U S A 95(18):10602-7. 1998
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| 12 | WBP4
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| Formin binding proteins bear WWP/WW domains that bind proline-rich peptides andfunctionally resemble SH3 domains.
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| Chan DC, Bedford MT, Leder P.
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| EMBO J 15(5):1045-54. 1996
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