| 1 | WASL
|
| Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion.
|
| Frugtniet BA, Martin TA, Zhang L, Jiang WG.
|
| BMC Cancer 17(1):224. doi: 10.1186/s12885-017-3219-3.
2017
|
| 2 | GRB2, WASL
|
| Myogenic differentiation depends on the interplay of Grb2 and N-WASP.
|
| Mitra P, Thanabalu T.
|
| Biochim Biophys Acta 1864(3):487-497. doi: 10.1016/j.bbamcr.2016.12.011. Epub 2016 Dec 10.
2017
|
| 3 | CDC42, WASL, YAP1
|
| Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway.
|
| Huang Z, Zhang L, Chen Y, Zhang H, Zhang Q, Li R, Ma J, Li Z, Yu C, Lai Y, Lin T, Zhao X, Zhang B, Ye Z, Liu S, Wang W, Liang X, Liao R, Shi W.
|
| Cell Death Dis 7:e2142. doi: 10.1038/cddis.2016.51.
2016
|
| 4 | CDC42, WASL
|
| The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation.
|
| Palazzo A, Bluteau O, Messaoudi K, Marangoni F, Chang Y, Souquere S, Pierron G, Lapierre V, Zheng Y, Vainchenker W, Raslova H, Debili N.
|
| J Thromb Haemost 14(12):2524-2535. doi: 10.1111/jth.13519. Epub 2016 Nov 15.
2016
|
| 5 | NCK1, WASL
|
| Allosteric N-WASP activation by an inter-SH3 domain linker in Nck.
|
| Okrut J, Prakash S, Wu Q, Kelly MJ, Taunton J.
|
| Proc Natl Acad Sci U S A 112(47):E6436-45. doi: 10.1073/pnas.1510876112. Epub 2015 Nov 9.
2015
|
| 6 | WAS, WASL
|
| Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1α.
|
| Jain N, Thanabalu T.
|
| Sci Rep 5:15031. doi: 10.1038/srep15031.
2015
|
| 7 | WASL
|
| Role of N-WASP in Endothelial Monolayer Formation and Integrity.
|
| Mooren OL, Kim J, Li J, Cooper JA.
|
| J Biol Chem 290(30):18796-805. doi: 10.1074/jbc.M115.668285. Epub 2015 Jun 12.
2015
|
| 8 | CTTN, WASF2, WASL
|
| Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens.
|
| Han SP, Gambin Y, Gomez GA, Verma S, Giles N, Michael M, Wu SK, Guo Z, Johnston W, Sierecki E, Parton RG, Alexandrov K, Yap AS.
|
| J Biol Chem 289(11):7764-75. doi: 10.1074/jbc.M113.544478. Epub 2014 Jan 27.
2014
|
| 9 | BIN1, WASL
|
| N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.
|
| Falcone S, Roman W, Hnia K, Gache V, Didier N, Lainé J, Auradé F, Marty I, Nishino I, Charlet-Berguerand N, Romero NB, Marazzi G, Sassoon D, Laporte J, Gomes ER.
|
| EMBO Mol Med 6(11):1455-75. doi: 10.15252/emmm.201404436.
2014
|
| 10 | WASL
|
| N-wasp is required for structural integrity of the blood-testis barrier.
|
| Xiao X, Mruk DD, Tang EI, Massarwa R, Mok KW, Li N, Wong CK, Lee WM, Snapper SB, Shilo BZ, Schejter ED, Cheng CY.
|
| PLoS Genet 10(6):e1004447. doi: 10.1371/journal.pgen.1004447. eCollection 2014 Jun.
2014
|
| 11 | BCAR1, WASL
|
| N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.
|
| Zhang X, Moore SW, Iskratsch T, Sheetz MP.
|
| J Cell Sci 127(Pt 7):1394-405. doi: 10.1242/jcs.134692. Epub 2014 Jan 30.
2014
|
| 12 | CDC42, ITSN1, NCK1, WASL
|
| Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation.
|
| Humphries AC, Donnelly SK, Way M.
|
| J Cell Sci 127(Pt 3):673-85. doi: 10.1242/jcs.141366. Epub 2013 Nov 27.
2014
|
| 13 | NCK1, WASL, WIPF1
|
| WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization.
|
| Donnelly SK, Weisswange I, Zettl M, Way M.
|
| Curr Biol 23(11):999-1006. doi: 10.1016/j.cub.2013.04.051. Epub 2013 May 23.
2013
|
| 14 | WASL
|
| N-wasp is required for stabilization of podocyte foot processes.
|
| Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB.
|
| J Am Soc Nephrol 24(5):713-21. doi: 10.1681/ASN.2012080844. Epub 2013 Mar 7.
2013
|
| 15 | MMP14, WASL
|
| N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.
|
| Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM.
|
| J Cell Biol 199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22.
2012
|
| 16 | WASL
|
| N-WASP is required for membrane wrapping and myelination by Schwann cells.
|
| Novak N, Bar V, Sabanay H, Frechter S, Jaegle M, Snapper SB, Meijer D, Peles E.
|
| J Cell Biol 192(2):243-50.
2011
|
| 17 | ABI1, KCNN3, WASL
|
| An SK3 channel/nWASP/Abi-1 complex is involved in early neurogenesis.
|
| Liebau S, Steinestel J, Linta L, Kleger A, Storch A, Schoen M, Steinestel K, Proepper C, Bockmann J, Schmeisser MJ, Boeckers TM.
|
| PLoS One 6(3):e18148.
2011
|
| 18 | WASL, WIPF2
|
| N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway.
|
| Kovacs EM, Verma S, Ali RG, Ratheesh A, Hamilton NA, Akhmanova A, Yap AS.
|
| Nat Cell Biol 13(8):934-43. doi: 10.1038/ncb2290.
2011
|
| 19 | ENAH, PDGFA, WASF2, WASL
|
| WAVE2, N-WASP, and Mena facilitate cell invasion via phosphatidylinositol 3-kinase-dependent local accumulation of actin filaments.
|
| Takahashi K, Suzuki K.
|
| J Cell Biochem 112(11):3421-9. doi: 10.1002/jcb.23276.
2011
|
| 20 | WASF2, WASL
|
| IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function.
|
| Orange JS, Roy-Ghanta S, Mace EM, Maru S, Rak GD, Sanborn KB, Fasth A, Saltzman R, Paisley A, Monaco-Shawver L, Banerjee PP, Pandey R.
|
| J Clin Invest 121(4):1535-48. doi: 10.1172/JCI44862. Epub 2011 Mar 7.
2011
|
| 21 | WASL, WIPF3
|
| CR16 forms a complex with N-WASP in human testes.
|
| Xiang W, Wen Z, Pang W, Hu L, Xiong C, Zhang Y.
|
| Cell Tissue Res 344(3):519-26. doi: 10.1007/s00441-011-1159-9. Epub 2011 Apr 20.
2011
|
| 22 | GAS7, NCKIPSD, WASL
|
| Gas7 functions with N-WASP to regulate the neurite outgrowth of hippocampal neurons.
|
| You JJ, Lin-Chao S.
|
| J Biol Chem Biol Chem. 2010 Feb 11. [Epub ahead of print]PMID: 20150425 2010
|
| 23 | WASL
|
| Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice.
|
| Lyubimova A, Garber JJ, Upadhyay G, Sharov A, Anastasoaie F, Yajnik V, Cotsarelis G, Dotto GP, Botchkarev V, Snapper SB.
|
| J Clin Invest 120(2):446-56. doi: 10.1172/JCI36478. Epub 2010 Jan 11.PMID: 20071778 2010
|
| 24 | WASL
|
| N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways.
|
| Lefever T, Pedersen E, Basse A, Paus R, Quondamatteo F, Stanley AC, Langbein L, Wu X, Wehland J, Lommel S, Brakebusch C.
|
| J Cell Sci 123(Pt 1):128-40.PMID: 20016073 2010
|
| 25 | NEB, WASL
|
| Nebulin and N-WASP cooperate to cause IGF-1-induced sarcomeric actin filament formation.
|
| Takano K, Watanabe-Takano H, Suetsugu S, Kurita S, Tsujita K, Kimura S, Karatsu T, Takenawa T, Endo T.
|
| Science 330(6010):1536-40.
2010
|
| 26 | FNBP1L, WASL
|
| The Toca-1-N-WASP complex links filopodial formation to endocytosis.
|
| Bu W, Chou AM, Lim KB, Sudhaharan T, Ahmed S.
|
| J Biol Chem 284(17):11622-36. Epub 2009 Feb 11.PMID: 19213734 2009
|
| 27 | WASL
|
| N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses.
|
| Wegner AM, Nebhan CA, Hu L, Majumdar D, Meier KM, Weaver AM, Webb DJ.
|
| J Biol Chem 283(23):15912-20. Epub 2008 Apr 21.PMID: 18430734 2008
|
| 28 | WASL
|
| N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer.
|
| Martin TA, Pereira G, Watkins G, Mansel RE, Jiang WG.
|
| Clin Exp Metastasis 25(2):97-108. Epub 2007 Nov 6.PMID: 17985201 2008
|
| 29 | WAS, WASL
|
| Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.
|
| Cotta-de-Almeida V, Westerberg L, Maillard MH, Onaldi D, Wachtel H, Meelu P, Chung UI, Xavier R, Alt FW, Snapper SB.
|
| Proc Natl Acad Sci U S A 104(39):15424-9. Epub 2007 Sep 18. 2007
|
| 30 | SNX9, WASL, DNM1
|
| Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis.
|
| Shin N, Lee S, Ahn N, Kim SA, Ahn SG, YongPark Z, Chang S.
|
| J Biol Chem 282(39):28939-50. Epub 2007 Aug 6. 2007
|
| 31 | WASL
|
| N-WASP plays a critical role in fibroblast adhesion and spreading.
|
| Misra A, Lim RP, Wu Z, Thanabalu T.
|
| Biochem Biophys Res Commun 364(4):908-12. Epub 2007 Oct 24. 2007
|
| 32 | FGF2, FGFR1, IQGAP1, WASL
|
| IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly.
|
| Benseñor LB, Kan HM, Wang N, Wallrabe H, Davidson LA, Cai Y, Schafer DA, Bloom GS.
|
| J Cell Sci 120(Pt 4):658-69. Epub 2007 Jan 30.
2007
|
| 33 | WASL, CTTN
|
| A neural Wiskott-Aldrich Syndrome protein-mediated pathway for localized activation of actin polymerization that is regulated by cortactin.
|
| Kempiak SJ, Yamaguchi H, Sarmiento C, Sidani M, Ghosh M, Eddy RJ, Desmarais V, Way M, Condeelis J, Segall JE.
|
| J Biol Chem 280(7):5836-42. Epub 2004 Dec 4. 2005
|
| 34 | WIPF2, WIPF3, WASL
|
| WICH, a member of WASP-interacting protein family, cross-links actin filaments.
|
| Kato M, Takenawa T.
|
| Biochem Biophys Res Commun 328(4):1058-66. 2005
|
| 35 | WASL, CDC42, FNBP1L
|
| Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex.
|
| Ho HY, Rohatgi R, Lebensohn AM, Le Ma, Li J, Gygi SP, Kirschner MW.
|
| Cell 118(2):203-16. 2004
|
| 36 | WASL, WASF1
|
| Two verprolin homology domains increase the Arp2/3 complex-mediated actin polymerization activities of N-WASP and WAVE1 C-terminal regions.
|
| Yamaguchi H, Miki H, Takenawa T.
|
| Biochem Biophys Res Commun 297(2):214-9. 2002
|
| 37 | WIPF3, WASL
|
| CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family.
|
| Ho HY, Rohatgi R, Ma L, Kirschner MW.
|
| Proc Natl Acad Sci U S A 98(20):11306-11. Epub 2001 Sep 11. 2001
|
| 38 | WASL
|
| Signalling to actin: the Cdc42-N-WASP-Arp2/3 connection.
|
| Carlier MF, Ducruix A, Pantaloni D.
|
| Chem Biol 6(9):R235-40. Review. 1999
|
| 39 | WASL
|
| Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP.
|
| Miki H, et al.
|
| Nature 391(6662):93-6. 1998
|
| 40 | WASL
|
| Identification of N-WASP homologs in human and rat brain.
|
| Fukuoka M, et al.
|
| Gene 196(1-2):43-8. 1997
|