Citations for
1VSX2
Chx10 Consolidates V2a Interneuron Identity through Two Distinct Gene Repression Modes.
Clovis YM, Seo SY, Kwon JS, Rhee JC, Yeo S, Lee JW, Lee S, Lee SK.
Cell Rep 16(6):1642-52. doi: 10.1016/j.celrep.2016.06.100. Epub 2016 Jul 28. 2016
2VSX2
Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells.
Capowski EE, Wright LS, Liang K, Phillips MJ, Wallace K, Petelinsek A, Hagstrom A, Pinilla I, Borys K, Lien J, Min JH, Keles S, Thomson JA, Gamm DM.
Stem Cells tem Cells. 2016 Jun 14. doi: 10.1002/stem.2414. [Epub ahead of print] 2016
3VSX2
Chx10 functions as a regulator of molecular pathways controlling the regional identity in the primordial retina.
Wang Z, Yasugi S, Ishii Y.
Dev Biol 413(1):104-11. doi: 10.1016/j.ydbio.2016.03.023. Epub 2016 Mar 19. 2016
4DMBX1, VSX2
Coordinating progenitor cell cycle exit and differentiation in the developing vertebrate retina.
Miles A, Tropepe V.
Neurogenesis (Austin) 3(1):e1161697. doi: 10.1080/23262133.2016.1161697. eCollection 2016. 2016
5ASCL1, VSX2
VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures.
Wright LS, Pinilla I, Saha J, Clermont JM, Lien JS, Borys KD, Capowski EE, Phillips MJ, Gamm DM.
PLoS One 10(8):e0135830. doi: 10.1371/journal.pone.0135830. eCollection 2015. 2015
6MITF, VSX2
Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.
Sigulinsky CL, German ML, Leung AM, Clark AM, Yun S, Levine EM.
Neural Dev 10:12. doi: 10.1186/s13064-015-0039-5. 2015
7DMBX1, VSX2
Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression.
Wong L, Power N, Miles A, Tropepe V.
Dev Biol 402(2):216-28. doi: 10.1016/j.ydbio.2015.03.020. Epub 2015 Apr 11. 2015
8LHX3, VSX2
Lhx3-Chx10 reticulospinal neurons in locomotor circuits.
Bretzner F, Brownstone RM.
J Neurosci 33(37):14681-92. doi: 10.1523/JNEUROSCI.5231-12.2013. 2013
9VSX2
Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.
Zou C, Levine EM.
PLoS Genet 8(9):e1002924. doi: 10.1371/journal.pgen.1002924. Epub 2012 Sep 20. 2012
10VSX2
Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma.
Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM.
PLoS One 6(8):e23410. doi: 10.1371/journal.pone.0023410. Epub 2011 Aug 16. 2011
11NXNL1, VSX2
The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina.
Reichman S, Kalathur RK, Lambard S, Aït-Ali N, Yang Y, Lardenois A, Ripp R, Poch O, Zack DJ, Sahel JA, Léveillard T.
Hum Mol Genet 19(2):250-61. Epub 2009 Oct 20.PMID: 19843539 2010
12MCOP2, VSX2
Use of genome-wide SNP homozygosity mapping in small pedigrees to identify new mutations in VSX2 causing recessive microphthalmia and a semidominant inner retinal dystrophy.
Iseri SU, Wyatt AW, Nürnberg G, Kluck C, Nürnberg P, Holder GE, Blair E, Salt A, Ragge NK.
Hum Genet 128(1):51-60. Epub 2010 Apr 23.PMID: 20414678 2010
13PRDM1, VSX2
Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development.
Katoh K, Omori Y, Onishi A, Sato S, Kondo M, Furukawa T.
J Neurosci 30(19):6515-26. 2010
14PRDM1, VSX2
Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development.
Brzezinski JA 4th, Lamba DA, Reh TA.
Development 137(4):619-29. 2010
15VSX2
Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina.
Kokkinopoulos I, Pearson RA, Macneil A, Dhomen NS, MacLaren RE, Ali RR, Sowden JC.
Mol Cell Neurosci 38(3):359-73. Epub 2008 Apr 10. 2008
16VSX2
Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina.
Sigulinsky CL, Green ES, Clark AM, Levine EM.
Dev Biol 317(2):560-75. Epub 2008 Mar 14. 2008
17VSX1, VSX2
Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina.
Clark AM, Yun S, Veien ES, Wu YY, Chow RL, Dorsky RI, Levine EM.
Brain Res 1192:99-113. Epub 2007 Jun 18. 2008
18MCIA, MCOP2, VSX2
Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar.
Faiyaz-Ul-Haque M, Zaidi SH, Al-Mureikhi MS, Peltekova I, Tsui LC, Teebi AS.
Clin Genet 72(2):164-6. No abstract available. 2007
19VSX2
CHX10 targets a subset of photoreceptor genes.
Dorval KM, Bobechko BP, Fujieda H, Chen S, Zack DJ, Bremner R.
J Biol Chem 281(2):744-51. Epub 2005 Oct 18. 2006
20ALX4, PFM1, MNX1, SCRA, VSX1, KTCN1, VSX2, MCIA, SOPT, HESX1, HOXD13, PSDY2, MSX2, PFM2, SIX3, HPE2, DCS, SHOX
Homeodomain revisited: a lesson from disease-causing mutations.
Chi YI.
Hum Genet 116(6):433-44. Epub 2005 Feb 23. 2005
21VSX2
Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1.
Dorval KM, Bobechko BP, Ahmad KF, Bremner R.
J Biol Chem 280(11):10100-8. Epub 2005 Jan 12. 2005
22MCIA, VSX2
CHX10 mutations cause non-syndromic microphthalmia/anophthalmia in Arab and Jewish kindreds.
Bar-Yosef U, Abuelaish I, Harel T, Hendler N, Ofir R, Birk OS.
Hum Genet um Genet. 2004 Jul 15 [Epub ahead of print] 2004
23MCOP2, VSX2
CHX10 mutations cause non-syndromic microphthalmia/ anophthalmia in Arab and Jewish kindreds.
Bar-Yosef U, Abuelaish I, Harel T, Hendler N, Ofir R, Birk OS.
Hum Genet 115(4):302-9. 2004
24VSX2, MCIA
Human microphthalmia associated with mutations in the retinal homeobox gene CHX10.
Ferda Percin E, Ploder LA, Yu JJ, Arici K, Horsford DJ, Rutherford A, Bapat B, Cox DW, Duncan AM, Kalnins VI, Kocak-Altintas A, Sowden JC, Traboulsi E, Sarfarazi M, McInnes RR.
Nat Genet 25(4):397-401. 2000
25VSX2
Identification of neural progenitors in the adult mammalian eye.
Ahmad I, Tang L, Pham H.
Biochem Biophys Res Commun 270(2):517-21. 2000
26VSX2
Mammalian HOX10 and the nematode gene ceh-10 define a novel class of homeobox genes : evidence that HOX10 plays a fundamental role in mammalian retinal development.
Liu SC, et al.
Am J Hum Genet 51 : A55. 1992
27VSX2
Identification of a developmentally regulated human retinal homeobox gene.
De Chen J, et al.
Am J Hum Genet 45 : A111. 1989