Citations for
1PARK17, VPS26A, VPS29, VPS35
An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex.
Macías-Calvio V, Fuentealba LM, Marzolo MP.
J Neurosci Res. Jan;99(1):163-179. doi: 10.1002/jnr.24675. Epub 2020 Jul 7. 2021
2CCDC85C, KLF7, VPS35
KLF7/VPS35 axis contributes to hepatocellular carcinoma progression through CCDC85C-activated β-catenin pathway
Guo Y, Chai B, Jia J, Yang M, Li Y, Zhang R, Wang S, Xu J.
Cell Biosci. Apr 15;11(1):73. doi: 10.1186/s13578-021-00585-6. 2021
3TBC1D5, VPS26A, VPS29, VPS35
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain.
Ye H, Ojelade SA, Li-Kroeger D, Zuo Z, Wang L, Li Y, Gu JY, Tepass U, Rodal AA, Bellen HJ, Shulman JM.
Elife. Apr 14;9:e51977. doi: 10.7554/eLife.51977 2020
4AIMP2, VPS35
VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
Yun SP, Kim H, Ham S, Kwon SH, Lee GH, Shin JH, Lee SH, Ko HS, Lee Y.
Cell Death Dis. Apr 6;8(4):e2741. doi: 10.1038/cddis.2017.157. 2017
5EIF4G1, SNCA, VPS35
Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein.
Dhungel N, Eleuteri S, Li LB, Kramer NJ, Chartron JW, Spencer B, Kosberg K, Fields JA, Stafa K, Adame A, Lashuel H, Frydman J, Shen K, Masliah E, Gitler AD.
Neuron 85(1):76-87. doi: 10.1016/j.neuron.2014.11.027. Epub 2014 Dec 18. Erratum in: Neuron. 2015 Feb 4;85(3):657. 2015
6VPS26A, VPS29, VPS35
VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process
Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, Saiki S, Hattori N.
FEBS Lett. Jun 4;589(13):1430-6. doi: 10.1016/j.febslet.2015.04.040. Epub 2015 May 1 2015
7ANKRD27, TYRP1, VPS35
Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling.
McGough IJ, Steinberg F, Gallon M, Yatsu A, Ohbayashi N, Heesom KJ, Fukuda M, Cullen PJ.
J Cell Sci. Nov 15;127(Pt 22):4940-53. doi: 10.1242/jcs.156299. Epub 2014 Oct 2. 2014
8MAGEL2, TRIM27, VPS26A, VPS35
Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.
Hao YH, Doyle JM, Ramanathan S, Gomez TS, Jia D, Xu M, Chen ZJ, Billadeau DD, Rosen MK, Potts PR.
Cell 152(5):1051-64. doi: 10.1016/j.cell.2013.01.051. 2013
9PARK17, VPS35
Identification of VPS35 mutations replicated in French families with Parkinson disease.
Lesage S, Condroyer C, Klebe S, Honoré A, Tison F, Brefel-Courbon C, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group.
Neurology 78(18):1449-50. Epub 2012 Apr 18. No abstract available. 2012
10PARK17, VPS35
Screening for VPS35 mutations in Parkinson's disease.
Sheerin UM, Charlesworth G, Bras J, Guerreiro R, Bhatia K, Foltynie T, Limousin P, Silveira-Moriyama L, Lees A, Wood N.
Neurobiol Aging 33(4):838.e1-5. Epub 2011 Dec 7. 2012
11FAM21C, VPS35, WASH1
Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer.
Jia D, Gomez TS, Billadeau DD, Rosen MK.
Mol Biol Cell 23(12):2352-61. doi: 10.1091/mbc.E11-12-1059. Epub 2012 Apr 18. 2012
12PARK17, VPS35
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease.
Zimprich A, Benet-Pagès A, Struhal W, Graf E, Eck SH, Offman MN, Haubenberger D, Spielberger S, Schulte EC, Lichtner P, Rossle SC, Klopp N, Wolf E, Seppi K, Pirker W, Presslauer S, Mollenhauer B, Katzenschlager R, Foki T, Hotzy C, Reinthaler E, Harutyunyan A, Kralovics R, Peters A, Zimprich F, Brücke T, Poewe W, Auff E, Trenkwalder C, Rost B, Ransmayr G, Winkelmann J, Meitinger T, Strom TM.
Am J Hum Genet 89(1):168-75. 2011
13PARK17, VPS35
VPS35 mutations in Parkinson disease.
Vilariño-Güell C, Wider C, Ross OA, Dachsel JC, Kachergus JM, Lincoln SJ, Soto-Ortolaza AI, Cobb SA, Wilhoite GJ, Bacon JA, Behrouz B, Melrose HL, Hentati E, Puschmann A, Evans DM, Conibear E, Wasserman WW, Aasly JO, Burkhard PR, Djaldetti R, Ghika J, Hentati F, Krygowska-Wajs A, Lynch T, Melamed E, Rajput A, Rajput AH, Solida A, Wu RM, Uitti RJ, Wszolek ZK, Vingerhoets F, Farrer MJ.
Am J Hum Genet 89(1):162-7. Erratum in: Am J Hum Genet. 2011 Aug 12;89(2):347. 2011
14VPS35
VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.
Wen L, Tang FL, Hong Y, Luo SW, Wang CL, He W, Shen C, Jung JU, Xiong F, Lee DH, Zhang QG, Brann D, Kim TW, Yan R, Mei L, Xiong WC.
J Cell Biol 195(5):765-79. Epub 2011 Nov 21. 2011
15GLRB, GPHN, NBEA, VPS35
The trafficking proteins Vacuolar Protein Sorting 35 and Neurobeachin interact with the glycine receptor β-subunit.
del Pino I, Paarmann I, Karas M, Kilimann MW, Betz H.
Biochem Biophys Res Commun 412(3):435-40. Epub 2011 Jul 29. 2011
16VPS26, VPS29, VPS35
The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.
Harbour ME, Breusegem SY, Antrobus R, Freeman C, Reid E, Seaman MN.
J Cell Sci 123(Pt 21):3703-17. Epub 2010 Oct 5. 2010
17VPS35
Vps35 mediates vesicle transport between the mitochondria and peroxisomes.
Braschi E, Goyon V, Zunino R, Mohanty A, Xu L, McBride HM.
Curr Biol 20(14):1310-5. Epub 2010 Jul 8. 2010
18TBC1D5, VPS26A, VPS29, VPS35
Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.
Seaman MN, Harbour ME, Tattersall D, Read E, Bright N.
J Cell Sci 122(Pt 14):2371-82. Epub 2009 Jun 16. 2009
19VPS35
Functional architecture of the retromer cargo-recognition complex.
Hierro A, Rojas AL, Rojas R, Murthy N, Effantin G, Kajava AV, Steven AC, Bonifacino JS, Hurley JH.
Nature 449(7165):1063-7. Epub 2007 Sep 23. 2007
20VPS35
Dominant-negative behavior of mammalian Vps35 in yeast requires a conserved PRLYL motif involved in retromer assembly.
Zhao X, Nothwehr S, Lara-Lemus R, Zhang BY, Peter H, Arvan P.
Traffic 8(12):1829-40. Epub 2007 Oct 17. 2007
21VPS26, VPS26A, VPS35
Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval.
Reddy JV, Seaman MN.
Mol Biol Cell 12(10):3242-56. 2001
22SNX1, SNX2, VPS26A, VPS29, VPS35
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.
Haft CR, de la Luz Sierra M, Bafford R, Lesniak MA, Barr VA, Taylor SI.
Mol Biol Cell 11(12):4105-16. 2000
23VPS35
Cloning and characterization of human VPS35 and mouse Vps35 and mapping of VPS35 to human chromosome 16q13-q21.
Zhang P, Yu L, Gao J, Fu Q, Dai F, Zhao Y, Zheng L, Zhao S.
Genomics 70(2):253-7. 2000
24VPS29, VPS35
Human homologues of yeast vacuolar protein sorting 29 and 35.
Edgar AJ, Polak JM.
Biochem Biophys Res Commun 277(3):622-30. 2000
25VPS35
Genetic mapping and embryonic expression of a novel, maternally transcribed gene Mem3.
Hwang SY, et al.
Mamm Genome 7 : 586-590. 1996