| 1 | VCL
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| Mechanisms and Functions of Vinculin Interactions with Phospholipids at Cell Adhesion Sites.
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| Izard T, Brown DT.
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| J Biol Chem 291(6):2548-55. doi: 10.1074/jbc.R115.686493. Epub 2016 Jan 4. Review.
2016
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| 2 | VCL
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| The Structural Basis of Actin Organization by Vinculin and Metavinculin.
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| Kim LY, Thompson PM, Lee HT, Pershad M, Campbell SL, Alushin GM.
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| J Mol Biol 428(1):10-25. doi: 10.1016/j.jmb.2015.09.031. Epub 2015 Oct 20.
2016
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| 3 | TLN1, VCL
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| Vinculin controls talin engagement with the actomyosin machinery.
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| Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C.
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| Nat Commun 6:10038. doi: 10.1038/ncomms10038.
2015
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| 4 | VCL
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| A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.
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| Hernández-Varas P, Berge U, Lock JG, Strömblad S.
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| Nat Commun 6:7524. doi: 10.1038/ncomms8524.
2015
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| 5 | VCL
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| Vinculin-dependent actin bundling regulates cell migration and traction forces.
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| Jannie KM, Ellerbroek SM, Zhou DW, Chen S, Crompton DJ, García AJ, DeMali KA.
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| Biochem J 465(3):383-93. doi: 10.1042/BJ20140872.
2015
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| 6 | INPP5J, VCL
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| Lipid binding promotes oligomerization and focal adhesion activity of vinculin.
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| Chinthalapudi K, Rangarajan ES, Patil DN, George EM, Brown DT, Izard T.
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| J Cell Biol 207(5):643-56. doi: 10.1083/jcb.201404128.
2014
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| 7 | VCL
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| Identification of vinculin as a potential plasma marker for age-related macular degeneration.
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| Kim HJ, Woo SJ, Suh EJ, Ahn J, Park JH, Hong HK, Lee JE, Ahn SJ, Hwang DJ, Kim KW, Park KH, Lee C.
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| Invest Ophthalmol Vis Sci 55(11):7166-76. doi: 10.1167/iovs.14-15168.
2014
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| 8 | VCL
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| Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions.
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| Bays JL, Peng X, Tolbert CE, Guilluy C, Angell AE, Pan Y, Superfine R, Burridge K, DeMali KA.
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| J Cell Biol 205(2):251-63. doi: 10.1083/jcb.201309092. Epub 2014 Apr 21.
2014
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| 9 | VCL
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| Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.
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| Thompson PM, Tolbert CE, Shen K, Kota P, Palmer SM, Plevock KM, Orlova A, Galkin VE, Burridge K, Egelman EH, Dokholyan NV, Superfine R, Campbell SL.
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| Structure 22(5):697-706. doi: 10.1016/j.str.2014.03.002. Epub 2014 Mar 27.
2014
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| 10 | VCL
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| Vinculin regulates osteoclast function.
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| Fukunaga T, Zou W, Warren JT, Teitelbaum SL.
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| J Biol Chem 289(19):13554-64. doi: 10.1074/jbc.M114.550731. Epub 2014 Mar 27.
2014
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| 11 | TJP, VCL
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| Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes.
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| Zemljic-Harpf AE, Godoy JC, Platoshyn O, Asfaw EK, Busija AR, Domenighetti AA, Ross RS.
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| J Cell Sci 127(Pt 5):1104-16. doi: 10.1242/jcs.143743. Epub 2014 Jan 10.
2014
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| 12 | TJP1, VCL
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| Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes.
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| Zemljic-Harpf AE, Godoy JC, Platoshyn O, Asfaw EK, Busija AR, Domenighetti AA, Ross RS.
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| J Cell Sci 127(Pt 5):1104-16. doi: 10.1242/jcs.143743. Epub 2014 Jan 10.
2014
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| 13 | VCL
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| Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse.
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| Saez de Guinoa J, Barrio L, Carrasco YR.
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| J Immunol 191(5):2742-51. doi: 10.4049/jimmunol.1300684. Epub 2013 Jul 19.
2013
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| 14 | VCL
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| Deletion of the cell adhesion adaptor protein vinculin disturbs the localization of GFAP in Bergmann glial cells.
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| Winkler U, Hirrlinger PG, Sestu M, Wilhelm F, Besser S, Zemljic-Harpf AE, Ross RS, Bornschein G, Krügel U, Ziegler WH, Hirrlinger J.
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| Glia 61(7):1067-83. doi: 10.1002/glia.22495. Epub 2013 Apr 17.
2013
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| 15 | VCL
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| Novel role for vinculin in ventricular myocyte mechanics and dysfunction.
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| Tangney JR, Chuang JS, Janssen MS, Krishnamurthy A, Liao P, Hoshijima M, Wu X, Meininger GA, Muthuchamy M, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH.
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| Biophys J 104(7):1623-33. doi: 10.1016/j.bpj.2013.02.021.
2013
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| 16 | APBB1IP, VCL
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| RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
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| Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL.
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| J Biol Chem 288(12):8238-49. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6. 2013
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| 17 | VCL
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| Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner.
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| Carisey A, Tsang R, Greiner AM, Nijenhuis N, Heath N, Nazgiewicz A, Kemkemer R, Derby B, Spatz J, Ballestrem C.
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| Curr Biol 23(4):271-81. doi: 10.1016/j.cub.2013.01.009. Epub 2013 Jan 31.
2013
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| 18 | VCL
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| Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling.
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| Huveneers S, Oldenburg J, Spanjaard E, van der Krogt G, Grigoriev I, Akhmanova A, Rehmann H, de Rooij J.
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| J Cell Biol. 196(5):641-52. 2012
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| 19 | RAVER1, VCL
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| The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA.
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| Lee JH, Rangarajan ES, Vonrhein C, Bricogne G, Izard T.
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| J Mol Biol 422(5):697-704. doi: 10.1016/j.jmb.2012.06.015. Epub 2012 Jun 15.
2012
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| 20 | VCL
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| Vinculin functions as regulator of chondrogenesis.
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| Koshimizu T, Kawai M, Kondou H, Tachikawa K, Sakai N, Ozono K, Michigami T.
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| J Biol Chem 287(19):15760-75. doi: 10.1074/jbc.M111.308072. Epub 2012 Mar 13.
2012
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| 21 | VCL
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| The C-terminal tail domain of metavinculin, vinculin's splice variant, severs actin filaments.
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| Janssen ME, Liu H, Volkmann N, Hanein D.
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| J Cell Biol 197(5):585-93. doi: 10.1083/jcb.201111046. Epub 2012 May 21.
2012
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| 22 | VCL
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| Vinculin's C-terminal region facilitates phospholipid membrane insertion.
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| Wirth VF, List F, Diez G, Goldmann WH.
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| Biochem Biophys Res Commun. 398(3):433-7. 2010
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| 23 | VCL
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| Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini.
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| Palmer SM, Playford MP, Craig SW, Schaller MD, Campbell SL.
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| J Biol Chem 284(11):7223-31. Epub 2008 Dec 24.
2009
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| 24 | TLN1, VCL
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| Dystrophin-glycoprotein complex and vinculin-talin-integrin system in human adult cardiac muscle.
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| Anastasi G, Cutroneo G, Gaeta R, Di Mauro D, Arco A, Consolo A, Santoro G, Trimarchi F, Favaloro A.
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| Int J Mol Med 23(2):149-59.PMID: 19148538 2009
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| 25 | RBP1, VCL
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| Vinculin and cellular retinol-binding protein-1 are markers for quiescent and activated hepatic stellate cells in formalin-fixed paraffin embedded human liver.
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| Van Rossen E, Vander Borght S, van Grunsven LA, Reynaert H, Bruggeman V, Blomhoff R, Roskams T, Geerts A.
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| Histochem Cell Biol 131(3):313-25. Epub 2008 Dec 4.PMID: 19052772 2009
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| 26 | VCL
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| Direct evidence of vinculin tail-lipid membrane interaction in beta-sheet conformation.
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| Diez G, List F, Smith J, Ziegler WH, Goldmann WH.
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| Biochem Biophys Res Commun 373(1):69-73. Epub 2008 Jun 11.
2008
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| 27 | TLN1, VCL
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| Vinculin controls focal adhesion formation by direct interactions with talin and actin.
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| Humphries JD, Wang P, Streuli C, Geiger B, Humphries MJ, Ballestrem C.
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| J Cell Biol 179(5):1043-57. 2007
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| 28 | VCL
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| Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells.
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| Maddugoda MP, Crampton MS, Shewan AM, Yap AS.
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| J Cell Biol. 178(3):529-40 2007
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| 29 | VCL, CMD1W
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| Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy.
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| Vasile VC, Will ML, Ommen SR, Edwards WD, Olson TM, Ackerman MJ.
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| Mol Genet Metab 87(2):169-74. Epub 2005 Oct 19. 2006
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| 30 | VCL
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| Structural dynamics of alpha-actinin-vinculin interactions.
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| Bois PR, Borgon RA, Vonrhein C, Izard T.
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| Mol Cell Biol. 25(14):6112-22. 2005
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| 31 | TLN2, VCL
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| Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.
|
| Critchley DR.
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| Biochem Soc Trans 32(Pt 5):831-6. Review. 2004
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| 32 | VCL
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| The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading.
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| Zhang Z, Izaguirre G, Lin SY, Lee HY, Schaefer E, Haimovich B.
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| Mol Biol Cell. 15(9):4234-47. 2004
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| 33 | VCL
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| Vinculin activation by talin through helical bundle conversion.
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| Izard T, Evans G, Borgon RA, Rush CL, Bricogne G, Bois PR.
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| Nature. 427(6970):171-5. 2004
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| 34 | CMD1W, CMH1, CMH2, VCL
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| Dilated cardiomyopathy: a genetically heterogeneous disease.
|
| Shaw T,Elliott P,McKenna WJ.
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| Lancet 360(31):654-655. 2002
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| 35 | VCL
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| A lipid-regulated docking site on vinculin for protein kinase C.
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| Ziegler WH, Tigges U, Zieseniss A, Jockusch BM.
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| J Biol Chem. 277(9):7396-404. 2002
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| 36 | RAVER1, VCL
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| Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.
|
| Huttelmaier S, Illenberger S, Grosheva I, Rudiger M, Singer RH, Jockusch BM.
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| J Cell Biol 155(5):775-86. Epub 2001 Nov 26. 2001
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| 37 | PKD1, VCL
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| Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.
|
| Geng L, Burrow CR, Li HP, Wilson PD.
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| Biochim Biophys Acta. 1535(1):21-35. 2000
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| 38 | VCL
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| Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin.
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| Harbeck B, Hüttelmaier S, Schluter K, Jockusch BM, Illenberger S.
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| J Biol Chem. 275(40):30817-25. 2000
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| 39 | CORO2B, VCL
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| A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein.
|
| Nakamura T, et al.
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| J Biol Chem 274(19):13322-7 1999
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| 40 | VCL
|
| alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells.
|
| Watabe-Uchida M, Uchida N, Imamura Y, Nagafuchi A, Fujimoto K, Uemura T, Vermeulen S, van Roy F, Adamson ED, Takeichi M.
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| J Cell Biol. 142(3):847-57. 1998
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| 41 | VCL
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| Vinculin knockout results in heart and brain defects during embryonic development.
|
| Xu W, Baribault H, Adamson ED.
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| Development. 125(2):327-37. 1998
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| 42 | VCL
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| Vinculin is associated with the E-cadherin adhesion complex.
|
| Hazan RB, Kang L, Roe S, Borgen PI, Rimm DL.
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| J Biol Chem. 272(51):32448-53. 1997
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| 43 | VCL
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| Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.
|
| Brown MC, Perrotta JA, Turner CE.
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| J Cell Biol. 135(4):1109-23. 1996
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| 44 | VCL
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| F-actin binding site masked by the intramolecular association of vinculin head and tail domains.
|
| Johnson RP, Craig SW.
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| Nature. 373(6511):261-4. 1995
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| 45 | VCL
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| Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region.
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| Turner CE, Miller JT.
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| J Cell Sci. 107 ( Pt 6):1583-91. 1994
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| 46 | VCL
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| Interaction of vinculin with the clathrin heavy chain.
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| Fausser JL, Ungewickell E, Ruch JV, Lesot H.
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| J Biochem. 114(4):498-503. 1993
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| 47 | VCL
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| Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q.
|
| Mulligan LM, et al.
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| Genomics 13 : 1347-1349. 1992
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| 48 | VCL
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| An SphI polymorphism at the vinculin locus (VCL).
|
| Mulligan LM, et al.
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| Hum Mol Genet 1 : 550. 1992
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| 49 | VCL
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| Complete sequence of human vinculin and assignment of the gene to chromosome 10.
|
| Weller PA, et al.
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| Proc Natl Acad Sci U S A 87 : 5667-5671. 1990
|