| 1 | VAV3
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| Truncated isoform Vav3.1 is highly expressed in ovarian cancer stem cells and clinically relevant in predicting prognosis and platinum-response.
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| Reimer D, Boesch M, Wolf D, Marth C, Sopper S, Hatina J, Altevogt P, Parson W, Hackl H, Zeimet AG.
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| Int J Cancer 142(8):1640-1651. doi: 10.1002/ijc.31186. Epub 2017 Dec 14.
2018
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| 2 | VAV1, VAV2, VAV3
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| The C1 domain of Vav3, a novel potential therapeutic target.
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| Kelsey JS, Géczy T, Kaler CJ, Blumberg PM.
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| Cell Signal 40:133-142. doi: 10.1016/j.cellsig.2017.09.008. Epub 2017 Sep 18.
2017
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| 3 | VAV3
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| The clinical value of Vav3 in peripheral blood for predicting lymphatic metastasis of gastric cancer.
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| Tan B, Li Y, Wang C, Tan M, Fan L, Zhao Q, Wang D, Jia N.
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| Br J Biomed Sci 74(3):133-137. doi: 10.1080/09674845.2017.1278889. Epub 2017 May 17.
2017
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| 4 | VAV1, VAV3
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| Involvement of the guanine nucleotide exchange factor Vav3 in central nervous system development and plasticity.
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| Ulc A, Gottschling C, Schäfer I, Wegrzyn D, van Leeuwen S, Luft V, Reinhard J, Faissner A.
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| Biol Chem 398(5-6):663-675. doi: 10.1515/hsz-2016-0275. Review.
2017
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| 5 | VAV2, VAV3
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| Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors.
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| Perretta-Tejedor N, Fernández-Mateos J, García-Ortiz L, Gómez-Marcos MA, Recio-Rodríguez JI, Agudo-Conde C, Rodriguez-Sánchez E, Morales AI, López-Hernández FJ, López-Novoa JM, González-Sarmiento R, Martínez-Salgado C.
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| Sci Rep 7:41875. doi: 10.1038/srep41875. Erratum in: Sci Rep. 2018 May 11;8:46977.
2017
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| 6 | TNFRSF11A, TRAF6, VAV3
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| Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.
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| Yu J, Yun H, Shin B, Kim Y, Park ES, Choi S, Yu J, Amarasekara DS, Kim S, Inoue J, Walsh MC, Choi Y, Takami M, Rho J.
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| J Biol Chem 291(39):20643-60. doi: 10.1074/jbc.M116.728303. Epub 2016 Aug 9.
2016
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| 7 | VAV2, VAV3
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| VAV3 Gene Polymorphism Is Associated with Paget's Disease of Bone.
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| Usategui-Martín R, Calero-Paniagua I, García-Aparicio J, Corral-Gudino L, Del Pino Montes J, González Sarmiento R.
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| Genet Test Mol Biomarkers 20(6):335-7. doi: 10.1089/gtmb.2015.0292. Epub 2016 May 12.
2016
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| 8 | OSR2, PPFIA3, VAV3
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| Establishment of a DNA methylation marker to evaluate cancer cell fraction in gastric cancer
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| Zong L, Hattori N, Yoda Y, Yamashita S, Takeshima H, Takahashi T, Maeda M, Katai H, Nanjo S, Ando T, Seto Y, Ushijima T.
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| Gastric Cancer Apr;19(2):361-369. doi: 10.1007/s10120-015-0475-2. Epub 2015 Feb 13. 2016
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| 9 | VAV3
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| VAV3 oncogene expression in colorectal cancer: clinical aspects and functional characterization.
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| Uen YH, Fang CL, Hseu YC, Shen PC, Yang HL, Wen KS, Hung ST, Wang LH, Lin KY.
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| Sci Rep 5:9360. doi: 10.1038/srep09360.
2015
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| 10 | VAV3
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| The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina.
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| Luft V, Reinhard J, Shibuya M, Fischer KD, Faissner A.
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| Cell Tissue Res 359(2):423-440. doi: 10.1007/s00441-014-2050-2. Epub 2014 Dec 12. Erratum in: Cell Tissue Res. 2015 May;360(2):431-3.
2015
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| 11 | VAV3
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| The Vav3 oncogene enhances the malignant potential of prostate cancer cells under chronic hypoxia.
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| Hirai K, Nomura T, Yamasaki M, Inoue T, Narimatsu T, Chisato Nakada PD, Yoshiyuki Tsukamoto PD, Matsuura K, Sato F, Moriyama M, Mimata H.
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| Urol Oncol 32(2):101-9. doi: 10.1016/j.urolonc.2012.09.005. Epub 2013 Feb 9.
2014
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| 12 | VAV2, VAV3
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| The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.
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| Menacho-Márquez M, García-Escudero R, Ojeda V, Abad A, Delgado P, Costa C, Ruiz S, Alarcón B, Paramio JM, Bustelo XR.
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| PLoS Biol 11(7):e1001615. doi: 10.1371/journal.pbio.1001615. Epub 2013 Jul 23.
2013
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| 13 | VAV3
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| Novel interaction between the co-chaperone Cdc37 and Rho GTPase exchange factor Vav3 promotes androgen receptor activity and prostate cancer growth.
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| Wu F, Peacock SO, Rao S, Lemmon SK, Burnstein KL.
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| J Biol Chem 288(8):5463-74. doi: 10.1074/jbc.M112.390963. Epub 2012 Dec 31.
2013
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| 14 | RAC1, VAV3
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| Vav3-rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence.
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| Lin KT, Gong J, Li CF, Jang TH, Chen WL, Chen HJ, Wang LH.
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| Cancer Res 72(12):3000-9. doi: 10.1158/0008-5472.CAN-11-2502. Epub 2012 Jun 1.
2012
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| 15 | VAV3
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| A novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancer.
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| Rao S, Lyons LS, Fahrenholtz CD, Wu F, Farooq A, Balkan W, Burnstein KL.
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| Oncogene 31(6):716-27. doi: 10.1038/onc.2011.273. Epub 2011 Jul 18.
2012
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| 16 | VAV2, VAV3
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| The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.
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| Citterio C, Menacho-Márquez M, García-Escudero R, Larive RM, Barreiro O, Sánchez-Madrid F, Paramio JM, Bustelo XR.
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| Sci Signal 5(244):ra71. doi: 10.1126/scisignal.2002962.
2012
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| 17 | AHR, VAV3
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| Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene.
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| Sauzeau V, Carvajal-González JM, Riolobos AS, Sevilla MA, Menacho-Márquez M, Román AC, Abad A, Montero MJ, Fernández-Salguero P, Bustelo XR.
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| J Biol Chem 286(4):2896-909. doi: 10.1074/jbc.M110.187534. Epub 2010 Nov 29.
2011
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| 18 | VAV3
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| Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters.
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| Sauzeau V, Horta-Junior JA, Riolobos AS, Fernández G, Sevilla MA, López DE, Montero MJ, Rico B, Bustelo XR.
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| Mol Biol Cell 21(23):4251-63. doi: 10.1091/mbc.E10-07-0639. Epub 2010 Oct 6.
2010
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| 19 | VAV3
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| Vav3-deficient mice exhibit a transient delay in cerebellar development.
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| Quevedo C, Sauzeau V, Menacho-Márquez M, Castro-Castro A, Bustelo XR.
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| Mol Biol Cell 21(6):1125-39. doi: 10.1091/mbc.E09-04-0292. Epub 2010 Jan 20.
2010
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| 20 | VAV3
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| Vav3-deficient mice exhibit a transient delay in cerebellar development.
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| Quevedo C, Sauzeau V, Menacho-Márquez M, Castro-Castro A, Bustelo XR.
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| Mol Biol Cell 21(6):1125-39. doi: 10.1091/mbc.E09-04-0292. Epub 2010 Jan 20.
2010
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| 21 | VAV2, VAV3
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| Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo.
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| Brantley-Sieders DM, Zhuang G, Vaught D, Freeman T, Hwang Y, Hicks D, Chen J.
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| Mol Cancer Res 7(5):615-23. doi: 10.1158/1541-7786.MCR-08-0401. Epub 2009 May 12.
2009
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| 22 | VAV3
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| Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer.
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| Lee K, Liu Y, Mo JQ, Zhang J, Dong Z, Lu S.
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| BMC Cancer 8:158. doi: 10.1186/1471-2407-8-158.
2008
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| 23 | VAV3
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| Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction.
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| Sauzeau V, Sevilla MA, Rivas-Elena JV, de Alava E, Montero MJ, Lopez-Novoa JM, Bustelo XR.
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| Nat Med 12(7):841-845. Epub 2006 Jun 11. 2006
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| 24 | VAV3
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| Vav3 regulates osteoclast function and bone mass.
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| Faccio R, Teitelbaum SL, Fujikawa K, Chappel J, Zallone A, Tybulewicz VL, Ross FP, Swat W.
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| Nat Med 11(3):284-290. Epub 2005 Feb 13. 2005
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| 25 | VAV3
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| Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors.
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| Trenkle T, McClelland M, Adlkofer K, Welsh J.
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| Gene 245(1):139-49. 2000
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| 26 | VAV1, VAV2, VAV3
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| Genomic organization and regulation of the vav proto-oncogene.
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| Denkinger DJ, Borges CR, Butler CL, Cushman AM, Kawahara RS.
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| Biochim Biophys Acta 1491(1-3):253-62. 2000
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| 27 | VAV3
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| Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins.
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| Movilla N, Bustelo XR.
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| Mol Cell Biol 19(11):7870-85. 1999
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