| 1 | VAV1, VAV2, VAV3
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| The C1 domain of Vav3, a novel potential therapeutic target.
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| Kelsey JS, Géczy T, Kaler CJ, Blumberg PM.
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| Cell Signal 40:133-142. doi: 10.1016/j.cellsig.2017.09.008. Epub 2017 Sep 18.
2017
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| 2 | VAV2, VAV3
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| Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors.
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| Perretta-Tejedor N, Fernández-Mateos J, García-Ortiz L, Gómez-Marcos MA, Recio-Rodríguez JI, Agudo-Conde C, Rodriguez-Sánchez E, Morales AI, López-Hernández FJ, López-Novoa JM, González-Sarmiento R, Martínez-Salgado C.
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| Sci Rep 7:41875. doi: 10.1038/srep41875. Erratum in: Sci Rep. 2018 May 11;8:46977.
2017
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| 3 | CUX1, VAV2
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| Transcription factor CUX1 is required for intestinal epithelial wound healing and targets the VAV2-RAC1 Signalling complex.
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| Latreille R, Servant R, Darsigny M, Marcoux S, Jones C, Perreault N, Boudreau F.
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| Biochim Biophys Acta 1864(12):2347-2355. doi: 10.1016/j.bbamcr.2017.09.005. Epub 2017 Sep 8.
2017
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| 4 | VAV2
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| Upregulated Vav2 in gastric cancer tissues promotes tumor invasion and metastasis.
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| Tan BB, Li Y, Fan LQ, Zhao Q, Liu QW, Liu Y, Wang D, Jia N.
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| Tumour Biol 39(5):1010428317698392. doi: 10.1177/1010428317698392.
2017
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| 5 | VAV2, VAV3
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| VAV3 Gene Polymorphism Is Associated with Paget's Disease of Bone.
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| Usategui-Martín R, Calero-Paniagua I, García-Aparicio J, Corral-Gudino L, Del Pino Montes J, González Sarmiento R.
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| Genet Test Mol Biomarkers 20(6):335-7. doi: 10.1089/gtmb.2015.0292. Epub 2016 May 12.
2016
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| 6 | TXNIP, VAV2
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| Structural basis for a novel interaction between TXNIP and Vav2.
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| Liu S, Wu X, Zong M, Tempel W, Loppnau P, Liu Y.
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| FEBS Lett 590(6):857-65. doi: 10.1002/1873-3468.12110. Epub 2016 Mar 4.
2016
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| 7 | VAV2
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| VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.
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| Veluthakal R, Tunduguru R, Arora DK, Sidarala V, Syeda K, Vlaar CP, Thurmond DC, Kowluru A.
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| Diabetologia 58(11):2573-81. doi: 10.1007/s00125-015-3707-4. Epub 2015 Jul 31.
2015
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| 8 | GIT2, VAV2
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| Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration.
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| Jones MC, Machida K, Mayer BJ, Turner CE.
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| Mol Biol Cell 24(12):1882-94. doi: 10.1091/mbc.E12-09-0654.
2013
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| 9 | VAV2, VAV3
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| The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.
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| Menacho-Márquez M, García-Escudero R, Ojeda V, Abad A, Delgado P, Costa C, Ruiz S, Alarcón B, Paramio JM, Bustelo XR.
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| PLoS Biol 11(7):e1001615. doi: 10.1371/journal.pbio.1001615. Epub 2013 Jul 23.
2013
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| 10 | VAV2, VAV3
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| The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.
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| Citterio C, Menacho-Márquez M, García-Escudero R, Larive RM, Barreiro O, Sánchez-Madrid F, Paramio JM, Bustelo XR.
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| Sci Signal 5(244):ra71. doi: 10.1126/scisignal.2002962.
2012
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| 11 | ARAP3, VAV2
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| Identification and structural basis for a novel interaction between Vav2 and Arap3.
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| Wu B, Wang F, Zhang J, Zhang Z, Qin L, Peng J, Li F, Liu J, Lu G, Gong Q, Yao X, Wu J, Shi Y.
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| J Struct Biol 180(1):84-95. doi: 10.1016/j.jsb.2012.06.011. Epub 2012 Jun 28. 2012
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| 12 | RAC1, SSX2IP, VAV2
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| Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.
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| Fukumoto Y, Kurita S, Takai Y, Ogita H.
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| J Biol Chem 286(50):43537-48. doi: 10.1074/jbc.M111.308858. Epub 2011 Oct 25.
2011
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| 13 | EGFR, VAV2
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| VAV2 regulates epidermal growth factor receptor endocytosis and degradation.
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| Thalappilly S, Soubeyran P, Iovanna JL, Dusetti NJ.
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| Oncogene 29(17):2528-39. Epub 2010 Feb 8.
2010
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| 14 | FLNA, FLNB, KDR, RAC1, VAV2
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| Filamin B plays a key role in vascular endothelial growth factor-induced endothelial cell motility through its interaction with Rac-1 and Vav-2.
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| Del Valle-Pérez B, Martínez VG, Lacasa-Salavert C, Figueras A, Shapiro SS, Takafuta T, Casanovas O, Capellà G, Ventura F, Viñals F.
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| J Biol Chem 285(14):10748-60. Epub 2010 Jan 28. 2010
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| 15 | VAV2, VAV3
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| Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo.
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| Brantley-Sieders DM, Zhuang G, Vaught D, Freeman T, Hwang Y, Hicks D, Chen J.
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| Mol Cancer Res 7(5):615-23. doi: 10.1158/1541-7786.MCR-08-0401. Epub 2009 May 12.
2009
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| 16 | RAC1, VAV2
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| VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2.
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| Garrett TA, Van Buul JD, Burridge K.
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| Exp Cell Res 313(15):3285-97. Epub 2007 Jun 29.
2007
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| 17 | EGFR, VAV2
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| Persistent activation of Rac1 in squamous carcinomas of the head and neck: evidence for an EGFR/Vav2 signaling axis involved in cell invasion.
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| Patel V, Rosenfeldt HM, Lyons R, Servitja JM, Bustelo XR, Siroff M, Gutkind JS.
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| Carcinogenesis 28(6):1145-52. Epub 2007 Jan 18.
2007
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| 18 | VAV2
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| Vav family GEFs link activated Ephs to endocytosis and axon guidance.
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| Cowan CW, Shao YR, Sahin M, Shamah SM, Lin MZ, Greer PL, Gao S, Griffith EC, Brugge JS, Greenberg ME.
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| Neuron 46(2):205-17.
2005
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| 19 | VAV1, VAV2, VAV3
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| Genomic organization and regulation of the vav proto-oncogene.
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| Denkinger DJ, Borges CR, Butler CL, Cushman AM, Kawahara RS.
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| Biochim Biophys Acta 1491(1-3):253-62. 2000
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| 20 | VAV2
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| Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1.
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| Henske EP, et al.
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| Ann Hum Genet 59 : 25-37. 1995
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