Citations for
KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers.
Lee KH, Ahn EJ, Oh SJ, Kim O, Joo YE, Bae JA, Yoon S, Ryu HH, Jung S, Kim KK, Lee JH, Moon KS.
Oncotarget 6(5):3240-53. 2015
The homologous genes Vangl1 and Vangl2 are required for embryo implantation in the uterus of mice during early pregnancy.
Zhang H, Chen X, Zhao Y, Gao R, Geng Y, Ding Y, Liu X, Wang Y, He J.
Gene 555(2):140-9. doi: 10.1016/j.gene.2014.10.055. Epub 2014 Nov 1. 2015
Expanding the mutational spectrum associated to neural tube defects: literature revision and description of novel VANGL1 mutations.
Merello E, Mascelli S, Raso A, Piatelli G, Consales A, Cama A, Kibar Z, Capra V, Marco PD.
Birth Defects Res A Clin Mol Teratol 103(1):51-61. doi: 10.1002/bdra.23305. Epub 2014 Sep 10. 2015
Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer.
Hatakeyama J, Wald JH, Printsev I, Ho HY, Carraway KL 3rd.
Endocr Relat Cancer 21(5):R345-56. doi: 10.1530/ERC-14-0141. Epub 2014 Jun 30. 2014
Association between VANGL1 gene polymorphisms and neural tube defects.
Cai C, Shi O, Wang B, Chang B, Yang R, Wang Y, Wang F, Shen C.
Neuropediatrics 45(4):234-9. doi: 10.1055/s-0033-1364103. Epub 2014 Jan 9. 2014
Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals.
Pryor SE, Massa V, Savery D, Andre P, Yang Y, Greene ND, Copp AJ.
Development 141(16):3153-8. doi: 10.1242/dev.111427. Epub 2014 Jul 18. 2014
The intracellular carboxyl terminal domain of Vangl proteins contains plasma membrane targeting signals.
Iliescu A, Gros P.
Protein Sci 23(4):337-43. doi: 10.1002/pro.2432. Epub 2014 Mar 10. 2014
Vangl2, the planar cell polarity protein, is complexed with postsynaptic density protein PSD-95 [corrected].
Yoshioka T, Hagiwara A, Hida Y, Ohtsuka T.
FEBS Lett 587(10):1453-9. doi: 10.1016/j.febslet.2013.03.030. Epub 2013 Apr 6. Erratum in: FEBS Lett. 2013 Jul 11;587(14):2288. 2013
Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.
Belotti E, Puvirajesinghe TM, Audebert S, Baudelet E, Camoin L, Pierres M, Lasvaux L, Ferracci G, Montcouquiol M, Borg JP.
PLoS One 7(9):e46213. doi: 10.1371/journal.pone.0046213. Epub 2012 Sep 28. 2012
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.
Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT.
Oncogene 31(32):3696-708. doi: 10.1038/onc.2011.528. Epub 2011 Dec 19. 2012
Loss of membrane targeting of Vangl proteins causes neural tube defects.
Iliescu A, Gravel M, Horth C, Kibar Z, Gros P.
Biochemistry 50(5):795-804. Epub 2011 Jan 13. 2011
Transmembrane topology of mammalian planar cell polarity protein Vangl1.
Iliescu A, Gravel M, Horth C, Apuzzo S, Gros P.
Biochemistry 50(12):2274-82. doi: 10.1021/bi101767a. Epub 2011 Feb 25. 2011
VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.
Reynolds A, McDearmid JR, Lachance S, De Marco P, Merello E, Capra V, Gros P, Drapeau P, Kibar Z.
Mech Dev 127(7-8):385-92. doi: 10.1016/j.mod.2009.12.002. Epub 2010 Jan 4. 2010
Novel mutations in VANGL1 in neural tube defects.
Kibar Z, Bosoi CM, Kooistra M, Salem S, Finnell RH, De Marco P, Merello E, Bassuk AG, Capra V, Gros P.
Hum Mutat 30(7):E706-15.PMID: 19319979 2009
KITENIN recruits Dishevelled/PKC delta to form a functional complex and controls the migration and invasiveness of colorectal cancer cells.
Kho DH, Bae JA, Lee JH, Cho HJ, Cho SH, Lee JH, Seo YW, Ahn KY, Chung IJ, Kim KK.
Gut 58(4):509-19. Epub 2008 Jul 24.PMID: 18653728 2009
Mutations in VANGL1 associated with neural-tube defects.
Kibar Z, Torban E, McDearmid JR, Reynolds A, Berghout J, Mathieu M, Kirillova I, De Marco P, Merello E, Hayes JM, Wallingford JB, Drapeau P, Capra V, Gros P.
N Engl J Med 356(14):1432-7. 2007
Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium.
Kalabis J, Rosenberg I, Podolsky DK.
J Biol Chem 281(10):6434-41. Epub 2006 Jan 12.PMID: 16410243 2006
Expression of planar cell polarity genes during development of the mouse CNS.
Tissir F, Goffinet AM.
Eur J Neurosci 23(3):597-607.PMID: 16487141 2006
19VANGL1, CD82
KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer.
Lee JH, Park SR, Chay KO, Seo YW, Kook H, Ahn KY, Kim YJ, Kim KK.
Cancer Res 64(12):4235-43. 2004
Molecular cloning and characterization of Strabismus 2 (STB2).
Katoh M.
Int J Oncol 20(5):993-8. 2002
Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Yagyu R, Hamamoto R, Furukawa Y, Okabe H, Yamamura T, Nakamura Y.
Int J Oncol 20(6):1173-8. 2002