1 | SNTB2, UTRN
|
| The utrophin-beta 2 syntrophin complex regulates adipocyte lipid droplet size independent of adipogenesis.
|
| Krautbauer S, Neumeier M, Haberl EM, Pohl R, Feder S, Eisinger K, Rein-Fischboeck L, Buechler C.
|
| Mol Cell Biochem ol Cell Biochem. 2018 Jul 16. doi: 10.1007/s11010-018-3409-6. [Epub ahead of print]
2018
|
2 | FHL1, NFATC1, UTRN
|
| Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy.
|
| D'Arcy CE, Feeney SJ, McLean CA, Gehrig SM, Lynch GS, Smith JE, Cowling BS, Mitchell CA, McGrath MJ.
|
| Hum Mol Genet 23(3):618-36. doi: 10.1093/hmg/ddt449. Epub 2013 Sep 18.
2014
|
3 | UTRN
|
| Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.
|
| Tan N, Lansman JB.
|
| J Physiol 592(Pt 15):3303-23. doi: 10.1113/jphysiol.2014.274332. Epub 2014 May 30.
2014
|
4 | UTRN
|
| The actin binding affinity of the utrophin tandem calponin-homology domain is primarily determined by its N-terminal domain.
|
| Singh SM, Bandi S, Winder SJ, Mallela KM.
|
| Biochemistry 53(11):1801-9. doi: 10.1021/bi500149q. Epub 2014 Mar 14.
2014
|
5 | DMD, UTRN
|
| Microtubule binding distinguishes dystrophin from utrophin.
|
| Belanto JJ, Mader TL, Eckhoff MD, Strandjord DM, Banks GB, Gardner MK, Lowe DA, Ervasti JM.
|
| Proc Natl Acad Sci U S A 111(15):5723-8. doi: 10.1073/pnas.1323842111. Epub 2014 Mar 31.
2014
|
6 | DMD, UTRN
|
| Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice.
|
| van Putten M, Hulsker M, Young C, Nadarajah VD, Heemskerk H, van der Weerd L, 't Hoen PA, van Ommen GJ, Aartsma-Rus AM.
|
| FASEB J 27(6):2484-95. doi: 10.1096/fj.12-224170. Epub 2013 Mar 4.
2013
|
7 | DMD, UTRN
|
| UtroUp is a novel six zinc finger artificial transcription factor that recognises 18 base pairs of the utrophin promoter and efficiently drives utrophin upregulation.
|
| Onori A, Pisani C, Strimpakos G, Monaco L, Mattei E, Passananti C, Corbi N.
|
| BMC Mol Biol 14:3. doi: 10.1186/1471-2199-14-3.
2013
|
8 | DMD, SSPN, UTRN
|
| Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice.
|
| Marshall JL, Chou E, Oh J, Kwok A, Burkin DJ, Crosbie-Watson RH.
|
| Hum Mol Genet 21(20):4378-93. Epub 2012 Jul 13.
2012
|
9 | AKT1, SSPN, UTRN
|
| Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.
|
| Marshall JL, Holmberg J, Chou E, Ocampo AC, Oh J, Lee J, Peter AK, Martin PT, Crosbie-Watson RH.
|
| J Cell Biol 197(7):1009-27. doi: 10.1083/jcb.201110032.
2012
|
10 | DMD, UTRN
|
| Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.
|
| van Putten M, Kumar D, Hulsker M, Hoogaars WM, Plomp JJ, van Opstal A, van Iterson M, Admiraal P, van Ommen GJ, 't Hoen PA, Aartsma-Rus A.
|
| Neuromuscul Disord 22(5):406-17. doi: 10.1016/j.nmd.2011.10.011. Epub 2012 Jan 27.
2012
|
11 | DMD, UTRN
|
| Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.
|
| Singh SM, Molas JF, Kongari N, Bandi S, Armstrong GS, Winder SJ, Mallela KM.
|
| Proteins 80(5):1377-92. doi: 10.1002/prot.24033. Epub 2012 Feb 17.
2012
|
12 | UTRN
|
| Tissue expression and actin binding of a novel N-terminal utrophin isoform.
|
| Zuellig RA, Bornhauser BC, Amstutz R, Constantin B, Schaub MC.
|
| J Biomed Biotechnol 2011:904547. doi: 10.1155/2011/904547. Epub 2011 Nov 14.
2011
|
13 | UTRN
|
| Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice.
|
| Albesa M, Ogrodnik J, Rougier JS, Abriel H.
|
| Cardiovasc Res 89(2):320-8. doi: 10.1093/cvr/cvq326. Epub 2010 Oct 14.
2011
|
14 | DUP6QD, UTRN
|
| Molecular characterization of a de novo 6q24.2q25.3 duplication interrupting UTRN in a patient with arthrogryposis.
|
| Tabet AC, Aboura A, Gérard M, Pilorge M, Dupont C, Gadisseux JF, Hervy N, Pipiras E, Delahaye A, Kanafani S, Verloes A, Benzacken B, Betancur C.
|
| Am J Med Genet A 152A(7):1781-1788. [Epub ahead of print]PMID: 20583184 2010
|
15 | DMD, UTRN
|
| Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.
|
| Perronnet C, Vaillend C.
|
| J Biomed Biotechnol 2010:849426. Epub 2010 Jun 17. Review.PMID: 20625423 2010
|
16 | DMD, UTRN
|
| Dystrophin and utrophin have distinct effects on the structural dynamics of actin.
|
| Prochniewicz E, Henderson D, Ervasti JM, Thomas DD.
|
| Proc Natl Acad Sci U S A 106(19):7822-7. Epub 2009 Apr 30.
2009
|
17 | ITGA7, UTRN
|
| Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin.
|
| Welser JV, Rooney JE, Cohen NC, Gurpur PB, Singer CA, Evans RA, Haines BA, Burkin DJ.
|
| Am J Pathol 175(4):1545-54. doi: 10.2353/ajpath.2009.090052. Epub 2009 Sep 3.
2009
|
18 | UTRN
|
| Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function.
|
| Lu Y, Tian C, Danialou G, Gilbert R, Petrof BJ, Karpati G, Nalbantoglu J.
|
| J Biol Chem 283(50):34720-7. Epub 2008 Oct 21.
2008
|
19 | SSPN, UTRN
|
| Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex.
|
| Peter AK, Marshall JL, Crosbie RH.
|
| J Cell Biol 183(3):419-27. doi: 10.1083/jcb.200808027.
2008
|
20 | ADRA1, UTRN
|
| Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
|
| Lyssand JS, DeFino MC, Tang XB, Hertz AL, Feller DB, Wacker JL, Adams ME, Hague C.
|
| J Biol Chem 283(27):18792-800. doi: 10.1074/jbc.M801860200. Epub 2008 May 9.
2008
|
21 | UTRN
|
| UTRN on chromosome 6q24 is mutated in multiple tumors.
|
| Li Y, Huang J, Zhao YL, He J, Wang W, Davies KE, Nosé V, Xiao S.
|
| Oncogene 26(42):6220-8. Epub 2007 Mar 26.
2007
|
22 | UTRN
|
| Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.
|
| Perkins KJ, Basu U, Budak MT, Ketterer C, Baby SM, Lozynska O, Lunde JA, Jasmin BJ, Rubinstein NA, Khurana TS.
|
| Mol Biol Cell 18(8):2864-72. Epub 2007 May 16.
2007
|
23 | DMD, SYNM, UTRN
|
| Interactions of intermediate filament protein synemin with dystrophin and utrophin.
|
| Bhosle RC, Michele DE, Campbell KP, Li Z, Robson RM.
|
| Biochem Biophys Res Commun 346(3):768-77. Epub 2006 Jun 9.
2006
|
24 | DMD, UTRN
|
| ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan.
|
| Ishikawa-Sakurai M, Yoshida M, Imamura M, Davies KE, Ozawa E.
|
| Hum Mol Genet 13(7):693-702. Epub 2004 Feb 12. 2004
|
25 | UTRN, DMD
|
| Comparative analysis of the human dystrophin and utrophin gene structures.
|
| Pozzoli U, Sironi M, Cagliani R, Comi GP, Bardoni A, Bresolin N.
|
| Genetics 160(2):793-8. 2002
|
26 | UTRN
|
| The 2.0 A structure of the second calponin homology domain from the actin-binding region of the dystrophin homologue utrophin.
|
| Keep NH, et al.
|
| J Mol Biol 285(3):1257-64. 1999
|
27 | UTRN
|
| Up71 and Up140, two novel transcripts of utrophin that are homologues of short forms of dystrophin.
|
| Wilson J, et al.
|
| Hum Mol Genet 8(7):1271-1278. 1999
|
28 | UTRN
|
| Expression of the utrophin gene during myogenic differentiation.
|
| Gramolini AO, et al.
|
| Nucleic Acids Res 27(17):3603-3609. 1999
|
29 | UTRN
|
| G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed insensory ganglia and brain.
|
| Blake DJ, et al.
|
| Proc Natl Acad Sci U S A 92 : 3697-3701. 1995
|
30 | DAG1, UTRN
|
| A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering.
|
| Campanelli JT, et al.
|
| Cell 77 : 663-674. 1994
|
31 | DMD, UTRN
|
| The utrophin and dystrophin genes share similarities in genomic structure.
|
| Pearce M, et al.
|
| Hum Mol Genet 2 : 1765-1772. 1993
|
32 | D6S129, UTRN
|
| Localization of two new DNA markers on the linkage map of human chromosome 6q.
|
| Byth BC, et al.
|
| Cytogenet Cell Genet 60 : 216-218. 1992
|
33 | UTRN
|
| A (CA)n dinucleotide repeat polymorphism within the DMDL gene on chromosome 6q24.
|
| Byth BC, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1908-1909. 1991
|
34 | UTRN
|
| Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus.
|
| Buckle VJ, et al.
|
| Hum Genet 85 : 324-326. 1990
|
35 | UTRN
|
| Further characterisation of the chromosome 6 gene (DMDL) showing homology to dystrophin.
|
| Love DR, et al.
|
| Am J Hum Genet 47 : A227. 1990
|
36 | UTRN
|
| Identification of a chromosome 6-encoded dystrophin-related protein.
|
| Khurana TS, et al.
|
| J Biol Chem 265 : 16717-16720. 1990
|
37 | UTRN
|
| An autosomal transcript in skeletal muscle with homology to dystrophin.
|
| Love DR, et al.
|
| Nature 339 : 55-58. 1989
|
38 | UTRN
|
| Assignment of a dystrophin-related autosomal gene to 6q24.
|
| Buckle VJ, et al.
|
| (HGM10) Cytogenet Cell Genet 51 : 972. 1989
|