Citations for
1SNTB2, UTRN
The utrophin-beta 2 syntrophin complex regulates adipocyte lipid droplet size independent of adipogenesis.
Krautbauer S, Neumeier M, Haberl EM, Pohl R, Feder S, Eisinger K, Rein-Fischboeck L, Buechler C.
Mol Cell Biochem ol Cell Biochem. 2018 Jul 16. doi: 10.1007/s11010-018-3409-6. [Epub ahead of print] 2018
2FHL1, NFATC1, UTRN
Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy.
D'Arcy CE, Feeney SJ, McLean CA, Gehrig SM, Lynch GS, Smith JE, Cowling BS, Mitchell CA, McGrath MJ.
Hum Mol Genet 23(3):618-36. doi: 10.1093/hmg/ddt449. Epub 2013 Sep 18. 2014
3UTRN
Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.
Tan N, Lansman JB.
J Physiol 592(Pt 15):3303-23. doi: 10.1113/jphysiol.2014.274332. Epub 2014 May 30. 2014
4UTRN
The actin binding affinity of the utrophin tandem calponin-homology domain is primarily determined by its N-terminal domain.
Singh SM, Bandi S, Winder SJ, Mallela KM.
Biochemistry 53(11):1801-9. doi: 10.1021/bi500149q. Epub 2014 Mar 14. 2014
5DMD, UTRN
Microtubule binding distinguishes dystrophin from utrophin.
Belanto JJ, Mader TL, Eckhoff MD, Strandjord DM, Banks GB, Gardner MK, Lowe DA, Ervasti JM.
Proc Natl Acad Sci U S A 111(15):5723-8. doi: 10.1073/pnas.1323842111. Epub 2014 Mar 31. 2014
6DMD, UTRN
Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice.
van Putten M, Hulsker M, Young C, Nadarajah VD, Heemskerk H, van der Weerd L, 't Hoen PA, van Ommen GJ, Aartsma-Rus AM.
FASEB J 27(6):2484-95. doi: 10.1096/fj.12-224170. Epub 2013 Mar 4. 2013
7DMD, UTRN
UtroUp is a novel six zinc finger artificial transcription factor that recognises 18 base pairs of the utrophin promoter and efficiently drives utrophin upregulation.
Onori A, Pisani C, Strimpakos G, Monaco L, Mattei E, Passananti C, Corbi N.
BMC Mol Biol 14:3. doi: 10.1186/1471-2199-14-3. 2013
8DMD, SSPN, UTRN
Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice.
Marshall JL, Chou E, Oh J, Kwok A, Burkin DJ, Crosbie-Watson RH.
Hum Mol Genet 21(20):4378-93. Epub 2012 Jul 13. 2012
9AKT1, SSPN, UTRN
Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.
Marshall JL, Holmberg J, Chou E, Ocampo AC, Oh J, Lee J, Peter AK, Martin PT, Crosbie-Watson RH.
J Cell Biol 197(7):1009-27. doi: 10.1083/jcb.201110032. 2012
10DMD, UTRN
Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.
van Putten M, Kumar D, Hulsker M, Hoogaars WM, Plomp JJ, van Opstal A, van Iterson M, Admiraal P, van Ommen GJ, 't Hoen PA, Aartsma-Rus A.
Neuromuscul Disord 22(5):406-17. doi: 10.1016/j.nmd.2011.10.011. Epub 2012 Jan 27. 2012
11DMD, UTRN
Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.
Singh SM, Molas JF, Kongari N, Bandi S, Armstrong GS, Winder SJ, Mallela KM.
Proteins 80(5):1377-92. doi: 10.1002/prot.24033. Epub 2012 Feb 17. 2012
12UTRN
Tissue expression and actin binding of a novel N-terminal utrophin isoform.
Zuellig RA, Bornhauser BC, Amstutz R, Constantin B, Schaub MC.
J Biomed Biotechnol 2011:904547. doi: 10.1155/2011/904547. Epub 2011 Nov 14. 2011
13UTRN
Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice.
Albesa M, Ogrodnik J, Rougier JS, Abriel H.
Cardiovasc Res 89(2):320-8. doi: 10.1093/cvr/cvq326. Epub 2010 Oct 14. 2011
14DUP6QD, UTRN
Molecular characterization of a de novo 6q24.2q25.3 duplication interrupting UTRN in a patient with arthrogryposis.
Tabet AC, Aboura A, Gérard M, Pilorge M, Dupont C, Gadisseux JF, Hervy N, Pipiras E, Delahaye A, Kanafani S, Verloes A, Benzacken B, Betancur C.
Am J Med Genet A 152A(7):1781-1788. [Epub ahead of print]PMID: 20583184 2010
15DMD, UTRN
Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.
Perronnet C, Vaillend C.
J Biomed Biotechnol 2010:849426. Epub 2010 Jun 17. Review.PMID: 20625423 2010
16DMD, UTRN
Dystrophin and utrophin have distinct effects on the structural dynamics of actin.
Prochniewicz E, Henderson D, Ervasti JM, Thomas DD.
Proc Natl Acad Sci U S A 106(19):7822-7. Epub 2009 Apr 30. 2009
17ITGA7, UTRN
Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin.
Welser JV, Rooney JE, Cohen NC, Gurpur PB, Singer CA, Evans RA, Haines BA, Burkin DJ.
Am J Pathol 175(4):1545-54. doi: 10.2353/ajpath.2009.090052. Epub 2009 Sep 3. 2009
18UTRN
Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function.
Lu Y, Tian C, Danialou G, Gilbert R, Petrof BJ, Karpati G, Nalbantoglu J.
J Biol Chem 283(50):34720-7. Epub 2008 Oct 21. 2008
19SSPN, UTRN
Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex.
Peter AK, Marshall JL, Crosbie RH.
J Cell Biol 183(3):419-27. doi: 10.1083/jcb.200808027. 2008
20ADRA1, UTRN
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
Lyssand JS, DeFino MC, Tang XB, Hertz AL, Feller DB, Wacker JL, Adams ME, Hague C.
J Biol Chem 283(27):18792-800. doi: 10.1074/jbc.M801860200. Epub 2008 May 9. 2008
21UTRN
UTRN on chromosome 6q24 is mutated in multiple tumors.
Li Y, Huang J, Zhao YL, He J, Wang W, Davies KE, Nosé V, Xiao S.
Oncogene 26(42):6220-8. Epub 2007 Mar 26. 2007
22UTRN
Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.
Perkins KJ, Basu U, Budak MT, Ketterer C, Baby SM, Lozynska O, Lunde JA, Jasmin BJ, Rubinstein NA, Khurana TS.
Mol Biol Cell 18(8):2864-72. Epub 2007 May 16. 2007
23DMD, SYNM, UTRN
Interactions of intermediate filament protein synemin with dystrophin and utrophin.
Bhosle RC, Michele DE, Campbell KP, Li Z, Robson RM.
Biochem Biophys Res Commun 346(3):768-77. Epub 2006 Jun 9. 2006
24DMD, UTRN
ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan.
Ishikawa-Sakurai M, Yoshida M, Imamura M, Davies KE, Ozawa E.
Hum Mol Genet 13(7):693-702. Epub 2004 Feb 12. 2004
25UTRN, DMD
Comparative analysis of the human dystrophin and utrophin gene structures.
Pozzoli U, Sironi M, Cagliani R, Comi GP, Bardoni A, Bresolin N.
Genetics 160(2):793-8. 2002
26UTRN
The 2.0 A structure of the second calponin homology domain from the actin-binding region of the dystrophin homologue utrophin.
Keep NH, et al.
J Mol Biol 285(3):1257-64. 1999
27UTRN
Up71 and Up140, two novel transcripts of utrophin that are homologues of short forms of dystrophin.
Wilson J, et al.
Hum Mol Genet 8(7):1271-1278. 1999
28UTRN
Expression of the utrophin gene during myogenic differentiation.
Gramolini AO, et al.
Nucleic Acids Res 27(17):3603-3609. 1999
29UTRN
G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed insensory ganglia and brain.
Blake DJ, et al.
Proc Natl Acad Sci U S A 92 : 3697-3701. 1995
30DAG1, UTRN
A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering.
Campanelli JT, et al.
Cell 77 : 663-674. 1994
31DMD, UTRN
The utrophin and dystrophin genes share similarities in genomic structure.
Pearce M, et al.
Hum Mol Genet 2 : 1765-1772. 1993
32D6S129, UTRN
Localization of two new DNA markers on the linkage map of human chromosome 6q.
Byth BC, et al.
Cytogenet Cell Genet 60 : 216-218. 1992
33UTRN
A (CA)n dinucleotide repeat polymorphism within the DMDL gene on chromosome 6q24.
Byth BC, et al.
(HGM11) Cytogenet Cell Genet 58 : 1908-1909. 1991
34UTRN
Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus.
Buckle VJ, et al.
Hum Genet 85 : 324-326. 1990
35UTRN
Further characterisation of the chromosome 6 gene (DMDL) showing homology to dystrophin.
Love DR, et al.
Am J Hum Genet 47 : A227. 1990
36UTRN
Identification of a chromosome 6-encoded dystrophin-related protein.
Khurana TS, et al.
J Biol Chem 265 : 16717-16720. 1990
37UTRN
An autosomal transcript in skeletal muscle with homology to dystrophin.
Love DR, et al.
Nature 339 : 55-58. 1989
38UTRN
Assignment of a dystrophin-related autosomal gene to 6q24.
Buckle VJ, et al.
(HGM10) Cytogenet Cell Genet 51 : 972. 1989