1 | USP5
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| USP5 Promotes Metastasis in Non-Small Cell Lung Cancer by Inducing Epithelial-Mesenchymal Transition via Wnt/β-Catenin Pathway
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| Xue S, Wu W, Wang Z, Lu G, Sun J, Jin X, Xie L, Wang X, Tan C, Wang Z, Wang W, Ding X.
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| Front Pharmacol. May 8;11:668. doi: 10.3389/fphar.2020.00668. Erratum in: Front Pharmacol. 2020 Jun 24;11:948. 2020
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2 | CACNA1H, USP5
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| SUMOylation regulates USP5-Cav3.2 calcium channel interactions
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| Garcia-Caballero A, Zhang FX, Chen L, M'Dahoma S, Huang J, Zamponi GW.
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| Mol Brain. Aug 27;12(1):73. doi: 10.1186/s13041-019-0493-9. 2019
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3 | USP13, USP5
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| Deubiquitylases USP5 and USP13 are recruited to and regulate heat-induced stress granules through their deubiquitylating activities.
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| Xie X, Matsumoto S, Endo A, Fukushima T, Kawahara H, Saeki Y, Komada M.
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| J Cell Sci. Apr 12;131(8):jcs210856. doi: 10.1242/jcs.210856. 2018
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4 | OTUD6A, TP53, USP5
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| Ubiquitin-specific peptidase 5 and ovarian tumor deubiquitinase 6A are differentially expressed in p53+/+ and p53-/- HCT116 cells
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| Kim SY, Kwon SK, Lee SY, Baek KH.
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| Int J Oncol. May;52(5):1705-1714. doi: 10.3892/ijo.2018.4302. Epub 2018 Mar 5. 2018
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5 | SMURF1, USP5
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| Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5
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| Qian G, Ren Y, Zuo Y, Yuan Y, Zhao P, Wang X, Cheng Q, Liu J, Zhang L, Guo T, Liu C, Zheng H.
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| Biochem Biophys Res Commun. Jun 3;474(3):491-496. doi: 10.1016/j.bbrc.2016.04.135. Epub 2016 Apr 29. 2016
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6 | CACNA1H, USP5
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| Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain.
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| Gadotti VM, Caballero AG, Berger ND, Gladding CM, Chen L, Pfeifer TA, Zamponi GW.
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| Mol Pain. Mar 14;11:12. doi: 10.1186/s12990-015-0011-8. 2015
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7 | UBA1, UBTD2, USP5
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| A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes
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| Song AX, Yang H, Gao YG, Zhou CJ, Zhang YH, Hu HY
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| PLoS One. Sep 10;9(9):e107509. doi: 10.1371/journal.pone.0107509. 2014
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8 | USP5
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| Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks
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| Nakajima S, Lan L, Wei L, Hsieh CL, Rapić-Otrin V, Yasui A, Levine AS.
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| PLoS One Jan 14;9(1):e84899. doi: 10.1371/journal.pone.0084899. 2014
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9 | USP5
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| Two ZnF-UBP domains in isopeptidase T (USP5).
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| Avvakumov GV, Walker JR, Xue S, Allali-Hassani A, Asinas A, Nair UB, Fang X, Zuo X, Wang YX, Wilkinson KD, Dhe-Paganon S.
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| Biochemistry. Feb 14;51(6):1188-98. doi: 10.1021/bi200854q. Epub 2012 Feb 3. 2012
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10 | USP13, USP5
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| Domain analysis reveals that a deubiquitinating enzyme USP13 performs non-activating catalysis for Lys63-linked polyubiquitin.
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| Zhang YH, Zhou CJ, Zhou ZR, Song AX, Hu HY.
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| PLoS One 6(12):e29362. Epub 2011 Dec 28.
2011
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11 | USP5
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| Zinc is required for the catalytic activity of the human deubiquitinating isopeptidase T.
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| Gabriel JM, Lacombe T, Carobbio S, Paquet N, Bisig R, Cox JA, Jaton JC.
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| Biochemistry 41(46):13755-66. 2002
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12 | USP5
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| Further characterization of the putative human isopeptidase T catalytic site.
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| Lacombe T, Gabriel JM.
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| FEBS Lett 531(3):469-74. 2002
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13 | C12orf57, CD4, EMG1, GNB3, GPR162, LEPREL2, LPCAT3, PHB2, SPSB2, TPI1, USP5
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| A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.
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| Ansari-Lari MA, Muzny DM, Lu J, Lu F, Lilley CE, Spanos S, Malley T, GibbsRA.
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| Genome Res 6(4):314-26. 1996
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14 | USP5
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| Metabolism of the polyubiquitin degradation signal : structure, mechanism, and role of isopeptidase T.
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| Wilkinson KD, et al.
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| Biochemistry 34 : 14535-14546. 1995
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15 | USP5
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| cDNA cloning of a human 100 kDa de-ubiquitinating enzyme : the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2).
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| Falquet L, et al.
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| FEBS Lett 376 : 233-237. 1995
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16 | USP5
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| Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T.
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| Wilkinson KD, Tashayev VL, O'Connor LB, Larsen CN, Kasperek E, Pickart CM.
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| Biochemistry 34(44):14535-46. 1995
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