1 | RNF168, RNF8, USP44
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| The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.
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| Mosbech A, Lukas C, Bekker-Jensen S, Mailand N.
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| J Biol Chem 288(23):16579-87. doi: 10.1074/jbc.M113.459917. Epub 2013 Apr 24.
2013
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2 | USP44
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| The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation.
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| Holland AJ, Cleveland DW.
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| J Clin Invest 122(12):4325-8. doi: 10.1172/JCI66420. Epub 2012 Nov 26. Erratum in: J Clin Invest. 2013 Feb 1;123(2):933.
2012
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3 | USP44
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| USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis.
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| Zhang Y, Foreman O, Wigle DA, Kosari F, Vasmatzis G, Salisbury JL, van Deursen J, Galardy PJ.
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| J Clin Invest 122(12):4362-74. doi: 10.1172/JCI63084. Epub 2012 Nov 26.
2012
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4 | RNF20, USP44
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| RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.
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| Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M, Feldmesser E, Brik A, Yu X, Hanna J, Aberdam D, Domany E, Oren M.
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| Mol Cell 46(5):662-73. doi: 10.1016/j.molcel.2012.05.023. Erratum in: Mol Cell. 2015 Oct 15;60(2):338.
2012
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5 | USP44
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| Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia.
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| Zhang Y, van Deursen J, Galardy PJ.
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| PLoS One 6(8):e23389. doi: 10.1371/journal.pone.0023389. Epub 2011 Aug 11.
2011
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6 | USP44
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| K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44.
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| Suresh B, Ramakrishna S, Lee HJ, Choi JH, Kim JY, Ahn WS, Baek KH.
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| Cell Biol Int 34(8):799-808. doi: 10.1042/CBI20090144.
2010
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7 | USP44
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| Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
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| Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER 3rd, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
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| Nature 446(7138):876-81.
2007
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8 | MED20, PAN2, USP24, USP30, USP31, USP34, USP35, USP36, USP37, USP38, USP40, USP41, USP42, USP43, USP44, USP45, USP46, USP47, USP48, USP50, USP51, USP53, USP54
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| Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.
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| Quesada V, Diaz-Perales A, Gutierrez-Fernandez A, Garabaya C, Cal S, Lopez-Otin C.
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| Biochem Biophys Res Commun 314(1):54-62. 2004
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9 | FREM1, OVCH2, USP48, TMPRSS7, DDI2, MPN2, TESSP2, C1RL, OVCH1, USP12P1, USP27X, USP30, USP35, USP36, USP37, USP38, USP39, USP40, USP41, USP42, USP43, USP44, USP45, USP46, USP47, MED20, USP50, USP51, USP31, USP32
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| Human and mouse proteases: a comparative genomic approach.
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| Puente XS, Sanchez LM, Overall CM, Lopez-Otin C.
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| Nat Rev Genet 4(7):544-58. Review. 2003
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