1 | ULK1, USP20
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| The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.
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| Kim JH, Seo D, Kim SJ, Choi DW, Park JS, Ha J, Choi J, Lee JH, Jung SM, Seo KW, Lee EW, Lee YS, Cheong H, Choi CY, Park SH.
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| EMBO Rep MBO Rep. 2018 Feb 27. pii: e44378. doi: 10.15252/embr.201744378. [Epub ahead of print]
2018
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2 | CLSPN, USP20
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| Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.
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| Wang C, Yang C, Ji J, Jiang J, Shi M, Cai Q, Yu Y, Zhu Z, Zhang J.
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| Int J Oncol nt J Oncol. 2017 Mar 8. doi: 10.3892/ijo.2017.3904. [Epub ahead of print]
2017
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3 | MAPK6, USP20
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| Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.
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| Mathien S, Déléris P, Soulez M, Voisin L, Meloche S.
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| Mol Cell Biol 37(9). pii: e00432-16. doi: 10.1128/MCB.00432-16. Print 2017 May 1.
2017
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4 | USP18, USP20
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| USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.
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| Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B.
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| Cell Res 26(12):1302-1319. doi: 10.1038/cr.2016.125. Epub 2016 Nov 1.
2016
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5 | ARRB2, USP20
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| Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.
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| Jean-Charles PY, Zhang L, Wu JH, Han SO, Brian L, Freedman NJ, Shenoy SK.
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| J Biol Chem 291(14):7450-64. doi: 10.1074/jbc.M115.687129. Epub 2016 Feb 2.
2016
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6 | ADRB2, NEDD4, USP20, USP33
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| Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.
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| Kommaddi RP, Jean-Charles PY, Shenoy SK.
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| J Biol Chem 290(14):8888-903. doi: 10.1074/jbc.M114.630541. Epub 2015 Feb 9.
2015
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7 | USP20, USP33
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| Regulation of neuronal morphogenesis and positioning by ubiquitin-specific proteases in the cerebellum.
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| Anckar J, Bonni A.
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| PLoS One 10(1):e0117076. doi: 10.1371/journal.pone.0117076. eCollection 2015. Erratum in: PLoS One. 2015;10(8):e0135535. PLoS One. 2015;1 2015
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8 | ATR, HERC2, USP20
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| HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.
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| Yuan J, Luo K, Deng M, Li Y, Yin P, Gao B, Fang Y, Wu P, Liu T, Lou Z.
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| Nucleic Acids Res 42(21):13110-21. doi: 10.1093/nar/gku1034. Epub 2014 Oct 29.
2014
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9 | CHEK1, CLSPN, HERC2, USP20
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| HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability.
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| Zhu M, Zhao H, Liao J, Xu X.
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| Nucleic Acids Res 42(21):13074-81. doi: 10.1093/nar/gku978. Epub 2014 Oct 17.
2014
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10 | RAD17, USP20
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| Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination.
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| Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M.
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| J Biol Chem 289(33):22739-48. doi: 10.1074/jbc.M114.550459. Epub 2014 Jun 12.
2014
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11 | USP20
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| Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling.
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| Yasunaga J, Lin FC, Lu X, Jeang KT.
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| J Virol 85(13):6212-9. doi: 10.1128/JVI.00079-11. Epub 2011 Apr 27.
2011
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12 | USP20, USP33
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| The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.
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| Berthouze M, Venkataramanan V, Li Y, Shenoy SK.
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| EMBO J 28(12):1684-96. doi: 10.1038/emboj.2009.128. Epub 2009 May 7.
2009
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13 | HIF1A, USP20
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| VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.
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| Li Z, Wang D, Messing EM, Wu G.
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| EMBO Rep 6(4):373-8. 2005
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14 | USP20
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| Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
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| Curcio-Morelli C, Zavacki AM, Christofollete M, Gereben B, de Freitas BC, Harney JW, Li Z, Wu G, Bianco AC.
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| J Clin Invest 112(2):189-96. 2003
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15 | USP20, USP33, VHL
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| Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.
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| Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G.
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| Biochem Biophys Res Commun 294(3):700-9. 2002
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16 | C9orf16, CCBL1, CIZ1, DOLPP1, USP20, ST6GALNAC4
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| Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes.
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| Gilley J, Fried M.
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| Hum Mol Genet 8(7):1313-20. 1999
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17 | AKAP2, AMOTL2, ANKRD6, ARSG, ASXL1, ATG4B, BAHD1, BIRC6, BTBD3, C6orf84, CAMK2A, CAMKK2, CARD8, CHSY1, CORO2A, CPEB3, DIP2C, DLGAP4, DNAJC16, DNAJC9, DZIP1, EFR3B, EXOC6B, FAIM2, FASTKD2, FNBP4, INPP5F, LRCH1, NLGN4Y, NLRP1, NRXN2, PADI2, PCNX, PDS5B, PLEKHA6, PSD3, R3HDM2, RPH3A, SBNO2, SEZ6L, STK38L, TBC1D30, THOC5, TLL2, USP20, ZBTB1, ZFP30
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| Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A,Kotani H, Nomura N, Ohara O.
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| DNA Res 6(1):63-70. 1999
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