1 | RORC, USP15
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| Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.
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| He Z, Wang F, Ma J, Sen S, Zhang J, Gwack Y, Zhou Y, Sun Z.
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| J Immunol 197(4):1148-58. doi: 10.4049/jimmunol.1600548. Epub 2016 Jul 18.
2016
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2 | USP15
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| Zebrafish transforming growth factor-β-stimulated clone 22 domain 3 (TSC22D3) plays critical roles in Bmp-dependent dorsoventral patterning via 2 deubiquitinating enzymes Usp15 and Otud4.
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| Tse WK, Jiang YJ, Wong CK.
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| Biochim Biophys Acta. 2013
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3 | USP15
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| The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit.
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| Faronato M, Patel V, Darling S, Dearden L, Clague MJ, Urbé S, Coulson JM.
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| Cell Cycle. 12(12) 2013
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4 | USP15
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| USP15 Negatively Regulates Nrf2 through Deubiquitination of Keap1.
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| Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD.
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| Mol Cell. 2013
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5 | KEAP1, NFE2L2, USP15
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| USP15 negatively regulates Nrf2 through deubiquitination of Keap1.
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| Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD.
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| Mol Cell 51(1):68-79. doi: 10.1016/j.molcel.2013.04.022. Epub 2013 May 30.
2013
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6 | USP15
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| Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.
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| Hayes SD, Liu H, MacDonald E, Sanderson CM, Coulson JM, Clague MJ, Urbé S.
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| J Biol Chem. 287(51):43007-18. 2012
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7 | USP15, USP4
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| Ubiquitin removal in the TGF-β pathway.
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| Aggarwal K, Massagué J.
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| Nat Cell Biol 14(7):656-7. doi: 10.1038/ncb2534.
2012
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8 | USP15
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| USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma.
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| Eichhorn PJ, Rodón L, Gonzàlez-Juncà A, Dirac A, Gili M, Martínez-Sáez E, Aura C, Barba I, Peg V, Prat A, Cuartas I, Jimenez J, García-Dorado D, Sahuquillo J, Bernards R, Baselga J, Seoane J.
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| Nat Med. 18(3):429-35. 2012
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9 | USP15
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| USP15 is a deubiquitylating enzyme for receptor-activated SMADs.
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| Inui M, Manfrin A, Mamidi A, Martello G, Morsut L, Soligo S, Enzo E, Moro S, Polo S, Dupont S, Cordenonsi M, Piccolo S.
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| Nat Cell Biol 13(11):1368-75. doi: 10.1038/ncb2346.
2011
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10 | USP15
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| Structure of the USP15 N-terminal domains: a β-hairpin mediates close association between the DUSP and UBL domains.
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| Harper S, Besong TM, Emsley J, Scott DJ, Dreveny I.
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| Biochemistry 50(37):7995-8004. doi: 10.1021/bi200726e. Epub 2011 Aug 26.
2011
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11 | USP15
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| Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
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| Elliott PR, Liu H, Pastok MW, Grossmann GJ, Rigden DJ, Clague MJ, Urbé S, Barsukov IL.
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| FEBS Lett 585(21):3385-90. doi: 10.1016/j.febslet.2011.09.040. Epub 2011 Oct 10.
2011
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12 | FHL1, USP15
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| Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice.
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| Isumi Y, Hirata T, Saitoh H, Miyakawa T, Murakami K, Kudoh G, Doi H, Ishibashi K, Nakajima H.
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| Biochem Biophys Res Commun 405(2):216-21. doi: 10.1016/j.bbrc.2011.01.012. Epub 2011 Jan 8.
2011
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13 | USP15
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| USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis.
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| Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M, Kuroda M.
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| Biochem Biophys Res Commun 388(2):366-71. doi: 10.1016/j.bbrc.2009.08.015. Epub 2009 Aug 8.
2009
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14 | USP15
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| The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability.
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| Vos RM, Altreuter J, White EA, Howley PM.
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| J Virol 83(17):8885-92. doi: 10.1128/JVI.00605-09. Epub 2009 Jun 24.
2009
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15 | USP15
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| Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development.
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| Tse WK, Eisenhaber B, Ho SH, Ng Q, Eisenhaber F, Jiang YJ.
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| BMC Genomics. 10.1186/1471-2164-10-637 2009
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16 | USP15
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| Solution structure of the human ubiquitin-specific protease 15 DUSP domain.
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| de Jong RN, Ab E, Diercks T, Truffault V, Daniels M, Kaptein R, Folkers GE.
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| J Biol Chem 281(8):5026-31. Epub 2005 Nov 18. 2006
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17 | USP15
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| The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1.
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| Hetfeld BK, Helfrich A, Kapelari B, Scheel H, Hofmann K, Guterman A, Glickman M, Schade R, Kloetzel PM, Dubiel W.
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| Curr Biol 15(13):1217-21.
2005
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18 | USP15
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| Isolation and characterization of the mouse ubiquitin-specific protease Usp15.
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| Angelats C, Wang XW, Jermiin LS, Copeland NG, Jenkins NA, Baker RT.
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| Mamm Genome 14(1):31-46. 2003
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19 | USP15
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| Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases.
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| Baker RT, Wang XW, Woollatt E, White JA, Sutherland GR.
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| Genomics 59(3):264-74. 1999
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20 | ADAMTSL2, ARMCX2, C2CD5, CACNA2D2, CEP104, CEP68, DHX16, ERAP1, GPRIN2, HDAC5, IFT140, IQSEC2, JAKMIP2, KIAA0513, KIAA0556, KIAA0564, KIAA0586, KIF5C, LCMT2, LRRC37A, MARCHF6, MED13, NCDN, PCLO, PIP5K1C, PLCB1, PLEKHG3, PPFIA4, PPRC1, PRPF4B, ProSAPiP1, RASA4, SARM1, SMC5, ST18, TRIM2, URB1, USP15, ZCCHC14, ZNF292, ZNF451
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| Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
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| Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O.
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| DNA Res 5(1):31-9. 1998
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21 | EIF4A1, USP15
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| USP15 Enhances Re-epithelialization Through Deubiquitinating EIF4A1 During Cutaneous Wound Repair.
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| Zhao Y, Huang X, Zhang Z, Zhang Y, Zhang G, Zan T, Li Q.
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