Citations for
1SMUG1, UNG
SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress.
Nagaria P, Svilar D, Brown AR, Wang XH, Sobol RW, Wyatt MD.
Mutat Res 743-744:26-32. doi: 10.1016/j.mrfmmm.2012.12.001. Epub 2012 Dec 17. 2013
2UNG
Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase.
Sharbeen G, Yee CW, Smith AL, Jolly CJ.
J Exp Med 209(5):965-74. doi: 10.1084/jem.20112379. Epub 2012 Apr 23. 2012
3PCNA, UNG
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.
Torseth K, Doseth B, Hagen L, Olaisen C, Liabakk NB, Græsmann H, Durandy A, Otterlei M, Krokan HE, Kavli B, Slupphaug G.
DNA Repair (Amst) 11(6):559-69. doi: 10.1016/j.dnarep.2012.03.006. Epub 2012 Apr 20. 2012
4RPA1, UNG
Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
Doseth B, Ekre C, Slupphaug G, Krokan HE, Kavli B.
DNA Repair (Amst) 11(6):587-93. doi: 10.1016/j.dnarep.2012.03.003. Epub 2012 Apr 6. 2012
5UNG
Uracil DNA N-glycosylase promotes assembly of human centromere protein A.
Zeitlin SG, Chapados BR, Baker NM, Tai C, Slupphaug G, Wang JY.
PLoS One 6(3):e17151. doi: 10.1371/journal.pone.0017151. 2011
6UNG, XRCC1
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes.
Akbari M, Solvang-Garten K, Hanssen-Bauer A, Lieske NV, Pettersen HS, Pettersen GK, Wilson DM 3rd, Krokan HE, Otterlei M.
DNA Repair (Amst) 9(7):785-95. doi: 10.1016/j.dnarep.2010.04.002. Epub 2010 May 13. 2010
7RPA2, UNG
Replication protein A 32 interacts through a similar binding interface with TIPIN, XPA, and UNG2.
Ali SI, Shin JS, Bae SH, Kim B, Choi BS.
Int J Biochem Cell Biol 42(7):1210-5. doi: 10.1016/j.biocel.2010.04.011. Epub 2010 Apr 22. 2010
8UNG
Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription.
Fenard D, Houzet L, Bernard E, Tupin A, Brun S, Mougel M, Devaux C, Chazal N, Briant L.
Nucleic Acids Res 37(18):6008-18. doi: 10.1093/nar/gkp673. Epub 2009 Aug 20. 2009
9UNG
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
Hagen L, Kavli B, Sousa MM, Torseth K, Liabakk NB, Sundheim O, Pena-Diaz J, Otterlei M, H¿rning O, Jensen ON, Krokan HE, Slupphaug G.
EMBO J 27(1):51-61. Epub 2007 Dec 13. 2008
10UNG
Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Parker JB, Bianchet MA, Krosky DJ, Friedman JI, Amzel LM, Stivers JT.
Nature 449(7161):433-7. Epub 2007 Aug 19. 2007
11NEIL1, NEIL2, SMUG1, UNG, TDG, MPG
Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition.
Broderick P, Bagratuni T, Vijayakrishnan J, Lubbe S, Chandler I, Houlston RS.
BMC Cancer 6:243. 2006
12SMUG1, UNG
SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair.
Di Noia JM, Rada C, Neuberger MS.
EMBO J 25(3):585-95. Epub 2006 Jan 12. 2006
13UNG
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair.
Lu X, Bocangel D, Nannenga B, Yamaguchi H, Appella E, Donehower LA.
Mol Cell 15(4):621-34. 2004
14UNG
Mutational analysis of arginine 276 in the leucine-loop of human uracil-DNA glycosylase.
Chen CY, Mosbaugh DW, Bennett SE.
J Biol Chem 279(46):48177-88. Epub 2004 Aug 31. 2004
15HIGM4, UNG
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.
Imai K, Slupphaug G, Lee WI, Revy P, Nonoyama S, Catalan N, Yel L, Forveille M, Kavli B, Krokan HE, Ochs HD, Fischer A, Durandy A.
Nat Immunol 4(10):1023-8. Epub 2003 Sep 7. 2003
16UNG
Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG.
Saikrishnan K, Bidya Sagar M, Ravishankar R, Roy S, Purnapatre K, Handa P, Varshney U, Vijayan M.
Acta Crystallogr D Biol Crystallogr 58(Pt 8):1269-76. Epub 2002 Jul 20. 2002
17UNG
Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase.
Haug T, et al.
Nucleic Acids Res 26 : 1449-1457. 1998
18UNG
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively.
Otterlei M, Haug T, Nagelhus TA, Slupphaug G, Lindmo T, Krokan HE.
Nucleic Acids Res 26(20):4611-7. 1998
19UNG
Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites.
Bharati S, Krokan HE, Kristiansen L, Otterlei M, Slupphaug G.
Nucleic Acids Res 26 : 4953-4959. 1998
20UNG
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.
Nilsen H, et al.
Nucleic Acids Res 25 : 750-755. 1997
21UNG
Human uracil-DNA glycosylase gene : sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1.
Haug T, et al.
Genomics 36 : 408-416. 1996
22UNG
BglII polymorphism in the UNG gene in 4 populations.
Skorpen F, et al.
Hum Mol Genet 3 : 522. 1994
23UNG
Nuclear and mitochondrial forms of human uracil-DNA glycolase are encoded by the same gene.
Slupphaug G, et al.
Nucleic Acids Res 21 : 2579-2584. 1993
24UNG
A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase.
Meyer-Siegler K, et al.
Proc Natl Acad Sci U S A 88 : 8460-8464. 1991
25UNG
Chromosomal assignment of human uracil-DNA glycosylase to chromosome 12.
Aasland R, et al.
Genomics 7 : 139-141. 1990
26UNG
Isolation and characterization of the human uracil DNA glycosylase gene.
Vollberg TM, Siegler KM, Cool BL, Sirover MA.
Proc Natl Acad Sci U S A 86 : 8693-8697. 1989