| 1 | STXBP1, UNC13A
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| Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release.
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| Ma C, Su L, Seven AB, Xu Y, Rizo J.
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| Science 339(6118):421-5. doi: 10.1126/science.1230473. Epub 2012 Dec 20.
2013
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| 2 | CADPS, STX1A, UNC13A
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| Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.
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| Parsaud L, Li L, Jung CH, Park S, Saw NM, Park S, Kim MY, Sugita S.
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| J Biol Chem 288(32):23050-63. doi: 10.1074/jbc.M113.494088. Epub 2013 Jun 25.
2013
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| 3 | UNC13A, UNC13B, UNC13C
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| The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.
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| Chen Z, Cooper B, Kalla S, Varoqueaux F, Young SM Jr.
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| J Neurosci 33(19):8336-51. doi: 10.1523/JNEUROSCI.5128-12.2013.
2013
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| 4 | UNC13A
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| UNC13A influences survival in Italian amyotrophic lateral sclerosis patients: a population-based study.
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| Chiò A, Mora G, Restagno G, Brunetti M, Ossola I, Barberis M, Ferrucci L, Canosa A, Manera U, Moglia C, Fuda G, Traynor BJ, Calvo A.
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| Neurobiol Aging 34(1):357.e1-5. doi: 10.1016/j.neurobiolaging.2012.07.016. Epub 2012 Aug 22.
2013
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| 5 | UNC13A
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| UNC13A is a modifier of survival in amyotrophic lateral sclerosis.
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| Diekstra FP, van Vught PW, van Rheenen W, Koppers M, Pasterkamp RJ, van Es MA, Schelhaas HJ, de Visser M, Robberecht W, Van Damme P, Andersen PM, van den Berg LH, Veldink JH.
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| Neurobiol Aging 33(3):630.e3-8. doi: 10.1016/j.neurobiolaging.2011.10.029. Epub 2011 Nov 25.
2012
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| 6 | STXBP1, UNC13A
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| Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex.
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| Ma C, Li W, Xu Y, Rizo J.
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| Nat Struct Mol Biol 18(5):542-9. Epub 2011 Apr 17.
2011
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| 7 | FBXO45, UNC13A
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| Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.
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| Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H.
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| J Biol Chem 285(6):3840-9. Epub 2009 Dec 7.PMID: 19996097 2010
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| 8 | STXBP1, UNC13A
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| Munc18 and Munc13 regulate early neurite outgrowth.
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| Broeke JH, Roelandse M, Luteijn MJ, Boiko T, Matus A, Toonen RF, Verhage M.
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| Biol Cell 102(8):479-88. doi: 10.1042/BC20100036.
2010
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| 9 | UNC13A
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| Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.
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| van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH Jr, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH.
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| Nat Genet 41(10):1083-7. Epub 2009 Sep 6.PMID: 19734901 2009
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| 10 | RIMS1, UNC13A
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| Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.
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| Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY.
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| Diabetes 56(10):2579-88. Epub 2007 Jul 16.
2007
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| 11 | UNC13A
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| Munc13-1 is required for the sustained release of insulin from pancreatic beta cells.
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| Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T.
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| Cell Metab 3(6):463-8. Epub 2006 May 11.
2006
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| 12 | UNC13A
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| Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.
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| Rossner S, Fuchsbrunner K, Lange-Dohna C, Hartlage-Rübsamen M, Bigl V, Betz A, Reim K, Brose N.
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| J Biol Chem 279(27):27841-4. Epub 2004 Apr 30.
2004
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| 13 | BSN, ERC2, RIMS1, UNC13A
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| Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.
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| Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y.
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| J Cell Biol 164(2):301-11.
2004
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| 14 | BSN, ERC2, RIMS1, UNC13A
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| Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.
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| Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y.
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| J Cell Biol 158(3):577-90. Epub 2002 Aug 5.
2002
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| 15 | ACAP3, AMBRA1, CMIP, CNTNAP3, CNTNAP4, CPEB4, DAB2IP, DDHD1, DISP2, EEPD1, EXOC4, FAM40A, HELZ2, ITPRIP, KIAA1683, KIAA1712, KIAA1715, KIAA1737, KIAA1751, KIAA1755, KIF21A, MTMR12, PHACTR1, PHF21A, PRDM16, RAPH1, RHOXF1, SEMA4B, SEMA4C, SET7, SH3BP5L, SPHKAP, SSH2, TET1, TEX2, TNKS1BP1, UBE2O, UNC13A, UNK, WNK2, ZCCHC2, ZFHX2, ZNF407, ZNF436
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| Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O.
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| DNA Res 7(6):347-55. 2000
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| 16 | UNC13A, UNC13B, UNC13C
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| Differential expression of two novel Munc13 proteins in rat brain.
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| Augustin I, Betz A, Herrmann C, Jo T, Brose N.
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| Biochem J 337 ( Pt 3):363-71.PMID: 9895278 1999
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