Citations for
Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.
Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, Hou YC, Griffith OL, Cheng GS, Novik K, Moore R, Luk M, Owen D, Brown CJ, Morin GB, Gill S, Tai IT, Marra MA.
Pharmacogenomics J 13(2):148-58. doi: 10.1038/tpj.2011.65. Epub 2012 Jan 17. 2013
Frequency of uridine monophosphate synthase Gly(213)Ala polymorphism in Caucasian gastrointestinal cancer patients and healthy subjects, investigated by means of new, rapid genotyping assays.
Gusella M, Bertolaso L, Bolzonella C, Pasini F, Padrini R.
Genet Test Mol Biomarkers 15(10):691-5. doi: 10.1089/gtmb.2011.0021. Epub 2011 Jun 1. 2011
High orotate phosphoribosyltransferase gene expression predicts complete response to chemoradiotherapy in patients with squamous cell carcinoma of the esophagus.
Kajiwara T, Nishina T, Hyodo I, Moriwaki T, Endo S, Nasu J, Hori S, Matsuura B, Hiasa Y, Onji M.
Oncology 76(5):342-9. doi: 10.1159/000209964. Epub 2009 Mar 23. 2009
Overexpression of orotate phosphoribosyl transferase in hormone-refractory prostate cancer.
Tanaka T, Kawashima H, Matsumura K, Yamashita-Hosono T, Yoshimura R, Kuratsukuri K, Harimoto K, Nakatani T.
Oncol Rep 21(1):33-7. 2009
Expression of orotate phosphoribosyltransferase in colorectal carcinoma: an immunohistochemical analysis in several components of neoplastic lesions.
Sanada Y, Yoshida K, Hihara J, Okada M.
Oncol Rep 20(5):1005-11. 2008
Expression of orotate phosphoribosyltransferase (OPRT) in hepatobiliary and pancreatic carcinoma.
Sanada Y, Yoshida K, Ohara M, Tsutani Y.
Pathol Oncol Res 13(2):105-13. Epub 2007 Jul 3. 2007
Regulation of ornithine decarboxylase.
Pegg AE.
J Biol Chem 281(21):14529-32. Epub 2006 Feb 3. Review. 2006
Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
Subhi AL, Tang B, Balsara BR, Altomare DA, Testa JR, Cooper HS, Hoffman JP, Meropol NJ, Kruger WD.
Clin Cancer Res 10(21):7290-6. 2004
Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families.
Suchi M, et al.
Am J Hum Genet 60 : 525-539. 1997
Localization of the gene for uridine monophosphate synthase to human chromosome region 3q13 by in situ hybridization.
Qumsiyeh MB, et al.
Genomics 5 : 160-162. 1989
Isolation and characterization of the orotidine 5'-monophosphate decarboxylase domain of the multifunctional protein uridine 5'-monophosphate synthase.
Floyd EE, Jones ME.
J Biol Chem 260(16):9443-51. 1985
Structural gene coding for multifunctional protein carrying orotate phosphoribosyltransferase and OMP decarboxylase activity is located on long arm of human chromosome 3.
Patterson D, et al.
Somatic Cell Genet 9 : 359-374. 1983
Hereditary orotic aciduria : type I and II.
Fox RM, et al.
Am J Med 55 : 791-798. 1973