| 1 | FAF2, UBQLN2
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| Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
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| Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C.
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| J Neurochem Neurochem. 2013 Nov 12. doi: 10.1111/jnc.12606. [Epub ahead of print]
2013
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| 2 | ALS15, UBQLN2
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| Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia.
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| Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, Bigio EH, Brooks BR, Ajroud K, Sufit RL, Haines JL, Mugnaini E, Pericak-Vance MA, Siddique T.
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| Nature 477(7363):211-5. doi: 10.1038/nature10353.
2011
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| 3 | UBQLN1, UBQLN2, UBQLN3, UBQLN4
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| Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
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| Rothenberg C, Srinivasan D, Mah L, Kaushik S, Peterhoff CM, Ugolino J, Fang S, Cuervo AM, Nixon RA, Monteiro MJ.
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| Hum Mol Genet 19(16):3219-32. Epub 2010 Jun 7.PMID: 20529957 2010
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| 4 | UBQLN1, UBQLN2, UBQLN3, UBQLN4
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| Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation.
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| N'diaye EN, Debnath J, Brown EJ.
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| Autophagy 5(4). [Epub ahead of print]
2009
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| 5 | RAD23A,UBQLN2
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| Ubiquitin receptor proteins hHR23a and hPLIC2 interact.
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| Kang Y, Zhang N, Koepp DM, Walters KJ.
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| J Mol Biol 365(4):1093-101. Epub 2006 Oct 21. 2007
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| 6 | UBQLN1, UBQLN2
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| Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin.
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| Massey LK, Mah AL, Monteiro MJ.
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| Biochem J 391(Pt 3):513-25. 2005
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| 7 | UBQLN2
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| The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome.
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| Kleijnen MF, Alarcon RM, Howley PM.
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| Mol Biol Cell 14(9):3868-75. Epub 2003 May 29. 2003
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| 8 | UBQLN2
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| Assignment of ubiquilin2 (UBQLN2) to human chromosome xp11. 23-->p11.1 by GeneBridge radiation hybrids.
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| Kaye FJ, Shows TB.
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| Cytogenet Cell Genet 89(1-2):116-7. No abstract available. 2000
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| 9 | UBQLN1, UBQLN2
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| The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
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| Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM.
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| Mol Cell 6(2):409-19. 2000
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