1 | BCL2L10, ESYT2, IGF1R, UBQLN1
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| The STI and UBA Domains of UBQLN1 Are Critical Determinants of Substrate Interaction and Proteostasis.
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| Kurlawala Z, Shah PP, Shah C, Beverly LJ.
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| J Cell Biochem 118(8):2261-2270. doi: 10.1002/jcb.25880. Epub 2017 Apr 25. 2017
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2 | ORAI1, UBQLN1
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| Ubiquilin 1 interacts with Orai1 to regulate calcium mobilization.
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| Lee JE, Jeon IS, Han NE, Song HJ, Kim EG, Choi JW, Song KD, Lee HK, Choi JK.
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| Mol Cells 35(1):41-6. doi: 10.1007/s10059-013-2268-7. Epub 2013 Jan 9.
2013
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3 | BCL2L10, UBQLN1
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| Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.
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| Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H.
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| Proc Natl Acad Sci U S A 109(3):E119-26. Epub 2012 Jan 10.
2012
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4 | APP, UBQLN1
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| Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688.
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| El Ayadi A, Stieren ES, Barral JM, Boehning D.
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| Proc Natl Acad Sci U S A 109(33):13416-21. doi: 10.1073/pnas.1206786109. Epub 2012 Jul 30.
2012
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5 | UBQLN1
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| Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein.
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| Stieren ES, El Ayadi A, Xiao Y, Siller E, Landsverk ML, Oberhauser AF, Barral JM, Boehning D.
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| J Biol Chem 286(41):35689-98. Epub 2011 Aug 18.
2011
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6 | TICAM1, UBQLN1
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| The ubiquitin-like protein PLIC-1 or ubiquilin 1 inhibits TLR3-Trif signaling.
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| Biswas N, Liu S, Ronni T, Aussenberg SE, Liu W, Fujita T, Wang T.
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| PLoS One 6(6):e21153. Epub 2011 Jun 17.
2011
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7 | UBQLN1, UBQLN2, UBQLN3, UBQLN4
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| Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
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| Rothenberg C, Srinivasan D, Mah L, Kaushik S, Peterhoff CM, Ugolino J, Fang S, Cuervo AM, Nixon RA, Monteiro MJ.
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| Hum Mol Genet 19(16):3219-32. Epub 2010 Jun 7.PMID: 20529957 2010
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8 | SPEM1, UBQLN1
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| UBQLN1 interacts with SPEM1 and participates in spermiogenesis.
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| Bao J, Zhang J, Zheng H, Xu C, Yan W.
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| Mol Cell Endocrinol 327(1-2):89-97. Epub 2010 Jun 14.
2010
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9 | UBQLN1, UBQLN2, UBQLN3, UBQLN4
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| Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation.
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| N'diaye EN, Debnath J, Brown EJ.
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| Autophagy 5(4). [Epub ahead of print]
2009
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10 | UBQLN1
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| Effects of ubiquilin 1 on the unfolded protein response.
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| Lu A, Hiltunen M, Romano DM, Soininen H, Hyman BT, Bertram L, Tanzi RE.
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| J Mol Neurosci 38(1):19-30. Epub 2008 Oct 25.
2009
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11 | UBQLN1
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| The ubiquitin-like protein Plic-1 enhances the membrane insertion of GABAA receptors by increasing their stability within the endoplasmic reticulum.
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| Saliba RS, Pangalos M, Moss SJ.
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| J Biol Chem 283(27):18538-44. Epub 2008 May 8.
2008
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12 | HTT, UBQLN1, HD
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| Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin.
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| Wang H, Lim PJ, Yin C, Rieckher M, Vogel BE, Monteiro MJ.
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| Hum Mol Genet 15(6):1025-41. Epub 2006 Feb 6. 2006
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13 | UBQLN1
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| The UBL domain of PLIC-1 regulates aggresome formation.
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| Heir R, Ablasou C, Dumontier E, Elliott M, Fagotto-Kaufmann C, Bedford FK.
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| EMBO Rep 7(12):1252-8. Epub 2006 Nov 3. 2006
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14 | UBQLN1, UBQLN2
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| Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin.
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| Massey LK, Mah AL, Monteiro MJ.
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| Biochem J 391(Pt 3):513-25. 2005
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15 | CHRNA3,CHRNA4,UBQLN1
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| Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors.
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| Ficklin MB, Zhao S, Feng G.
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| J Biol Chem 280(40):34088-95. Epub 2005 Aug 9. 2005
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16 | HES1, UBQLN1, ASCL1
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| Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells.
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| Persson P, Stockhausen MT, Pahlman S, Axelson H.
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| Int J Oncol 25(5):1213-21. 2004
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17 | MTOR, UBQLN1
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| Characterization of ubiquilin 1, an mTOR-interacting protein.
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| Wu S, Mikhailov A, Kallo-Hosein H, Hara K, Yonezawa K, Avruch J.
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| Biochim Biophys Acta 1542(1-3):41-56. 2002
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18 | UBQLN1
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| Molecular cloning and expression analysis of the human DA41 gene and its mapping to chromosome 9q21.2-q21.3.
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| Hanaoka E, Ozaki T, Ohira M, Nakamura Y, Suzuki M, Takahashi E, Moriya H, Nakagawara A, Sakiyama S.
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| J Hum Genet 45(3):188-91. 2000
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19 | UBQLN1, UBQLN2
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| The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
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| Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM.
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| Mol Cell 6(2):409-19. 2000
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20 | UBQLN1
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| Identification of a new cellular protein that can interact specifically with DAN.
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| Ozaki T, Hishiki T, Toyama Y, Yuasa S, Nakagawara A, Sakiyama S.
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| DNA Cell Biol 16(8):985-91. 1997
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21 | NBL1, UBQLN1
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| Identification of a new cellular protein that can interact specifically with DAN.
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| Ozaki T, Hishiki T, Toyama Y, Yuasa S, Nakagawara A, Sakiyama S.
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| DNA Cell Biol 16(8):985-91.
1997
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