| 1 | UBL4A
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| Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching.
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| Zhao Y, Lin Y, Zhang H, Mañas A, Tang W, Zhang Y, Wu D, Lin A, Xiang J.
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| Proc Natl Acad Sci U S A 112(31):9644-9. doi: 10.1073/pnas.1508647112. Epub 2015 Jul 20.
2015
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| 2 | BAG6, UBL4A
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| Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.
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| Kuwabara N, Minami R, Yokota N, Matsumoto H, Senda T, Kawahara H, Kato R.
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| J Biol Chem 290(15):9387-98. doi: 10.1074/jbc.M114.631804. Epub 2015 Feb 20.
2015
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| 3 | BAG6, GET4, UBL4A
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| Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
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| Mock JY, Chartron JW, Zaslaver M, Xu Y, Ye Y, Clemons WM Jr.
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| Proc Natl Acad Sci U S A 112(1):106-11. doi: 10.1073/pnas.1402745112. Epub 2014 Dec 22.
2015
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| 4 | AMFR, BAG6, UBL4A, USP13
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| USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
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| Liu Y, Soetandyo N, Lee JG, Liu L, Xu Y, Clemons WM Jr, Ye Y.
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| Elife 3:e01369. doi: 10.7554/eLife.01369. Epub 2014 Jan 14.
2014
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| 5 | BAG6, SGTA, UBL4A
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| Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A.
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| Darby JF, Krysztofinska EM, Simpson PJ, Simon AC, Leznicki P, Sriskandarajah N, Bishop DS, Hale LR, Alfano C, Conte MR, Martínez-Lumbreras S, Thapaliya A, High S, Isaacson RL.
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| PLoS One 9(11):e113281. doi: 10.1371/journal.pone.0113281. eCollection 2014.
2014
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| 6 | PTPN2, STAT3, UBL4A
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| GdX/UBL4A specifically stabilizes the TC45/STAT3 association and promotes dephosphorylation of STAT3 to repress tumorigenesis.
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| Wang Y, Ning H, Ren F, Zhang Y, Rong Y, Wang Y, Su F, Cai C, Jin Z, Li Z, Gong X, Zhai Y, Wang D, Jia B, Qiu Y, Tomita Y, Sung JJ, Yu J, Irwin DM, Yang X, Fu X, Chin YE, Chang Z.
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| Mol Cell 53(5):752-65. doi: 10.1016/j.molcel.2014.01.020. Epub 2014 Feb 13.
2014
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| 7 | ASNA1, GET4, UBL4A
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| Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway.
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| Rome ME, Chio US, Rao M, Gristick H, Shan SO.
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| Proc Natl Acad Sci U S A 111(46):E4929-35. doi: 10.1073/pnas.1411284111. Epub 2014 Nov 3.
2014
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| 8 | BAG6, GET4, UBL4A
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| Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death.
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| Krenciute G, Liu S, Yucer N, Shi Y, Ortiz P, Liu Q, Kim BJ, Odejimi AO, Leng M, Qin J, Wang Y.
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| J Biol Chem 288(28):20547-57. doi: 10.1074/jbc.M112.443416. Epub 2013 May 30.
2013
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| 9 | BAG6, GET4, UBL4A
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| A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation.
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| Xu Y, Liu Y, Lee JG, Ye Y.
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| J Biol Chem 288(25):18068-76. doi: 10.1074/jbc.M112.449199. Epub 2013 May 12.
2013
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| 10 | BAG6, SGTA, UBL4A
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| The association of BAG6 with SGTA and tail-anchored proteins.
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| Leznicki P, Roebuck QP, Wunderley L, Clancy A, Krysztofinska EM, Isaacson RL, Warwicker J, Schwappach B, High S.
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| PLoS One 8(3):e59590. doi: 10.1371/journal.pone.0059590. Epub 2013 Mar 22.
2013
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| 11 | ASNA1, GET4, UBL4A
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| Precise timing of ATPase activation drives targeting of tail-anchored proteins.
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| Rome ME, Rao M, Clemons WM, Shan SO.
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| Proc Natl Acad Sci U S A 110(19):7666-71. doi: 10.1073/pnas.1222054110. Epub 2013 Apr 22.
2013
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| 12 | UBL4A
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| Generation of mice with conditional null allele for GdX/Ubl4A.
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| Wang Y, Wang D, Ren F, Zhang Y, Lin F, Hou N, Cheng X, Zhang P, Wang Y, Jia B, Yang X, Chang Z.
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| Genesis 50(7):534-42. doi: 10.1002/dvg.20832. Epub 2012 Jan 24.
2012
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| 13 | SGTA, UBL4A
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| SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation.
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| Xu Y, Cai M, Yang Y, Huang L, Ye Y.
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| Cell Rep 2(6):1633-44. doi: 10.1016/j.celrep.2012.11.010. Epub 2012 Dec 13.
2012
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| 14 | ASNA1, GET4, UBL4A
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| Interaction surface and topology of Get3-Get4-Get5 protein complex, involved in targeting tail-anchored proteins to endoplasmic reticulum.
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| Chang YW, Lin TW, Li YC, Huang YS, Sun YJ, Hsiao CD.
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| J Biol Chem 287(7):4783-9. doi: 10.1074/jbc.M111.318329. Epub 2011 Dec 21.
2012
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| 15 | ASNA1, BAG6, GET4, UBL4A
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| A ribosome-associating factor chaperones tail-anchored membrane proteins.
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| Mariappan M, Li X, Stefanovic S, Sharma A, Mateja A, Keenan RJ, Hegde RS.
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| Nature 466(7310):1120-4. doi: 10.1038/nature09296. Epub 2010 Aug 1.
2010
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| 16 | UBL4A, UBL4B
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| Ubl4b, an X-derived retrogene, is specifically expressed in post-meiotic germ cells in mammals.
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| Yang F, Skaletsky H, Wang PJ.
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| Gene Expr Patterns 7(1-2):131-6. Epub 2006 Jun 14.
2007
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| 17 | ATP6AP1, DNASE1L1, DXS253E, DXS254E, EMD, FLNA, G6PD, GDI1, RGCP@, RPL10, UBL4A
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| Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.
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| Bione S, et al.
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| Proc Natl Acad Sci U S A 90 : 10977-10981. 1993
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| 18 | DXS254, UBL4A
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| A housekeeping gene on the X chromosome encodes a protein similar to ubiquitin.
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| Toniolo D, et al.
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| Proc Natl Acad Sci U S A 85 : 851-855. 1988
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