| 1 | MDM2, UBE4B
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| UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53.
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| Wu H, Pomeroy SL, Ferreira M, Teider N, Mariani J, Nakayama KI, Hatakeyama S, Tron VA, Saltibus LF, Spyracopoulos L, Leng RP.
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| Nat Med 17(3):347-55. Epub 2011 Feb 13.
2011
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| 2 | MDM2, UBE4B
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| UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation.
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| Wu H, Leng RP.
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| Cell Cycle 10(12):1912-5. Epub 2011 Jun 15. Review.
2011
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| 3 | TTK, UBE4B
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| Ubiquitin ligase Ufd2 is required for efficient degradation of Mps1 kinase.
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| Liu C, van Dyk D, Choe V, Yan J, Majumder S, Costanzo M, Bao X, Boone C, Huo K, Winey M, Fisk H, Andrews B, Rao H.
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| J Biol Chem 286(51):43660-7. doi: 10.1074/jbc.M111.286229. Epub 2011 Nov 1.
2011
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| 4 | UBE2D3, UBE4B
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| Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4.
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| Benirschke RC, Thompson JR, Nominé Y, Wasielewski E, Juranić N, Macura S, Hatakeyama S, Nakayama KI, Botuyan MV, Mer G.
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| Structure 18(8):955-65. 2010
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| 5 | UBE4B
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| Structural and functional characterization of the monomeric U-box domain from E4B.
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| Nordquist KA, Dimitrova YN, Brzovic PS, Ridenour WB, Munro KA, Soss SE, Caprioli RM, Klevit RE, Chazin WJ.
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| Biochemistry 49(2):347-55.
2010
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| 6 | UBE4B
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| U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.
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| Chatterjee A, Upadhyay S, Chang X, Nagpal JK, Trink B, Sidransky D.
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| Cell Cycle 7(9):1231-7. Epub 2008 Feb 19.
2008
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| 7 | UBE4A, UBE4B, NBL
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| The two human homologues of yeast UFD2 ubiquitination factor, UBE4A and UBE4B, are located in common neuroblastoma deletion regions and are subject to mutations in tumours.
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| Caren H, Holmstrand A, Sjoberg RM, Martinsson T.
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| Eur J Cancer 42(3):381-7. Epub 2006 Jan 4. 2006
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| 8 | UBE4B
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| The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death.
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| Spinette S, Mahoney JA, Rosen A.
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| Biochem Biophys Res Commun 347(4):1103-12. Epub 2006 Jul 14.
2006
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| 9 | ATXN3, UBE4B
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| Molecular clearance of ataxin-3 is regulated by a mammalian E4.
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| Matsumoto M, Yada M, Hatakeyama S, Ishimoto H, Tanimura T, Tsuji S, Kakizuka A, Kitagawa M, Nakayama KI.
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| EMBO J 23(3):659-69. Epub 2004 Jan 29. 2004
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| 10 | UBE4B
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| Screening for gene mutations in a 500 kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2.
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| Krona C, Ejeskar K, Abel F, Kogner P, Bjelke J, Bjork E, Sjoberg RM, Martinsson T.
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| Oncogene 22(15):2343-51. 2003
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| 11 | DFFA, KIF1B, PEX14, UBE4B
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| Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.
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| Ohira M, Kageyama H, Mihara M, Furuta S, Machida T, Shishikura T, Takayasu H, Islam A, Nakamura Y, Takahashi M, Tomioka N, Sakiyama S, Kaneko Y, Toyoda A, Hattori M, Sakaki Y, Ohki M, Horii A, Soeda E, Inazawa J, Seki N, Kuma H, Nozawa I, Nakagawara A.
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| Oncogene 19(37):4302-7. 2000
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| 12 | UBE4A, UBE4B
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| A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.
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| Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, Jentsch S.
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| Cell 96(5):635-44. 1999
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| 13 | AATK, ACIN1, ACOT11, ACSBG1, ADAMTS4, ADGRV1, AKAP11, ANKLE2, ARHGAP26, ARHGEF2, ASTN2, ATP2C2, ATP9A, BICD2, BZRAP1, C12orf51, CAND2, CEP135, CLASP1, CLASP2, CLUAP1, CLUH, CNOT3, COBL, CPNE3, CRTC1, CRY2, CSTF2T, CUL3, CUL4B, DAAM1, DAGLA, DEPDC5, DNAJC13, DOCK10, DZIP3, FBXW11, FKBP15, G3BP2, HEPH, HIP1R, HIPK1, ICOSLG, KIAA0649, KIAA0652, KIF13B, KIF1C, KIF21A, L3MBTL1, LDB3, MAGI2, MAP4K4, MFAP3L, MGEA5, MRC2, MTMR4, N4BP1, NPHP4, OBSL1, PAN2, PHACTR2, PHF2, PHLDB1, PLXND1, PPFIA3, PTCD1, RAB11FIP3, RBM19, RICH2, RNF40, RNF8, ROCK2, RRP12, SAPS2, SETX, SIN3B, SLC24A1, SMCHD1, SNAP91, SOCS5, SS18L1, SWAP70, TBC1D9B, TELO2, TNRC15, TSC22D2, UBE4B, UHRF1BP1L, ULK2, ZBED4, ZC3H11A, ZNF623
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| Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
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| Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N,Ohara O.
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| DNA Res 5(3):169-76. 1998
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