Citations for
1CDKN1B, UBE2L3
Stabilization of p27Kip1/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control.
Whitcomb EA, Tsai YC, Basappa J, Liu K, Le Feuvre AK, Weissman AM, Taylor A.
FASEB J ASEB J. 2018 Aug 16:fj201800960R. doi: 10.1096/fj.201800960R. [Epub ahead of print] 2018
2CASP1, UBE2L3
The Atypical Ubiquitin E2 Conjugase UBE2L3 Is an Indirect Caspase-1 Target and Controls IL-1β Secretion by Inflammasomes.
Eldridge MJG, Sanchez-Garrido J, Hoben GF, Goddard PJ, Shenoy AR.
Cell Rep 18(5):1285-1297. doi: 10.1016/j.celrep.2017.01.015. 2017
3UBE2L3
The haplotype of UBE2L3 gene is associated with Hashimoto's thyroiditis in a Chinese Han population.
Wang Y, Zhu YF, Wang Q, Xu J, Yan N, Xu J, Shi LF, He ST, Zhang JA.
BMC Endocr Disord 16:18. doi: 10.1186/s12902-016-0098-6. 2016
4ITCH, NDFIP1, UBE2L3
Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.
Kathania M, Zeng M, Yadav VN, Moghaddam SJ, Yang B, Venuprasad K.
J Immunol 194(5):2160-7. doi: 10.4049/jimmunol.1402742. Epub 2015 Jan 28. 2015
5UBE2L3
UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
Lewis MJ, Vyse S, Shields AM, Boeltz S, Gordon PA, Spector TD, Lehner PJ, Walczak H, Vyse TJ.
Am J Hum Genet 96(2):221-34. doi: 10.1016/j.ajhg.2014.12.024. Epub 2015 Jan 29. 2015
6MAP1B, UBE2L3
The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.
Gandini MA, Sandoval A, Zamponi GW, Felix R.
Channels (Austin) 8(5):452-7. doi: 10.4161/19336950.2014.949162. Erratum in: Channels (Austin). 2014;8(6):556. 2014
7TP53BP1, UBE2L3
UbcH7 regulates 53BP1 stability and DSB repair.
Han X, Zhang L, Chung J, Mayca Pozo F, Tran A, Seachrist DD, Jacobberger JW, Keri RA, Gilmore H, Zhang Y.
Proc Natl Acad Sci U S A 111(49):17456-61. doi: 10.1073/pnas.1408538111. Epub 2014 Nov 24. 2014
8PRKN, UBE2D2, UBE2D3, UBE2L3, UBE2N
The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy.
Geisler S, Vollmer S, Golombek S, Kahle PJ.
J Cell Sci 127(Pt 15):3280-93. doi: 10.1242/jcs.146035. Epub 2014 Jun 6. 2014
9UBE2L3
A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Wang S, Adrianto I, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Alarcón GS, Anaya JM, Bae SC, Kim JH, Joo YB, Boackle SA, Brown EE, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Wakeland EK, Moser KL, Montgomery CG, Gaffney PM.
Genes Immun 13(5):380-7. doi: 10.1038/gene.2012.6. Epub 2012 Apr 5. 2012
10ARIH1, PRKN, UBE2L3
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.
Wenzel DM, Lissounov A, Brzovic PS, Klevit RE.
Nature 474(7349):105-8. Epub 2011 May 1. 2011
11BCL3, UBE2L3
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease.
Fransen K, Visschedijk MC, van Sommeren S, Fu JY, Franke L, Festen EA, Stokkers PC, van Bodegraven AA, Crusius JB, Hommes DW, Zanen P, de Jong DJ, Wijmenga C, van Diemen CC, Weersma RK.
Hum Mol Genet 19(17):3482-8. Epub 2010 Jul 3. 2010
12UBE2L3
Kinetics of the transfer of ubiquitin from UbcH7 to E6AP.
Purbeck C, Eletr ZM, Kuhlman B.
Biochemistry 49(7):1361-3. 2010
13UBE2L3
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7.
Whitcomb EA, Dudek EJ, Liu Q, Taylor A.
Mol Biol Cell 20(1):1-9. Epub 2008 Oct 22. 2009
14ITCH, UBE2L3
Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7.
Raimondo D, Giorgetti A, Bernassola F, Melino G, Tramontano A.
Biochem Pharmacol 76(11):1620-7. Epub 2008 Aug 31. 2008
15RNF19B, UBE2L3, UBE2L6, UCKL1
NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.
Fortier JM, Kornbluth J.
J Immunol 176(11):6454-63. 2006
16ARIH1, UBE2L3
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7.
Ardley HC, Tan NG, Rose SA, Markham AF, Robinson PA.
J Biol Chem 276(22):19640-7. Epub 2001 Mar 13. 2001
17UBE2L1, UBE2L3, UBE2L4
Promoter analysis of the human ubiquitin-conjugating enzyme gene family UBE2L1-4, including UBE2L3 which encodes UbcH7.
Ardley HC, Moynihan TP, Markham AF, Robinson PA.
Biochim Biophys Acta 1491(1-3):57-64. 2000
18UBE2L3
Fine-mapping, genomic organization, and transcript analysis of the human ubiquitin-conjugating enzyme gene UBE2L3.
Moynihan TP, et al.
Genomics 51 : 124-127. 1998
19UBE2L1, UBE2L2, UBE2L3
Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3.
Moynihan TP, et al.
Mamm Genome 7 : 520-525. 1996