| 1 | RNF8, UBE2B
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| Function of RAD6B and RNF8 in spermatogenesis.
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| Guo Y, Song Y, Guo Z, Hu M, Liu B, Duan H, Wang L, Yuan T, Wang D.
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| Cell Cycle 17(2):162-173. doi: 10.1080/15384101.2017.1361066. Epub 2018 Jan 19.
2018
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| 2 | ASF1A, MDM2, UBE2A, UBE2B
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| A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis.
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| Wang C, Chang JF, Yan H, Wang DL, Liu Y, Jing Y, Zhang M, Men YL, Lu D, Yang XM, Chen S, Sun FL.
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| Oncotarget 6(30):29599-613. doi: 10.18632/oncotarget.5011.
2015
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| 3 | AR, UBE2B
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| Identification of Ube2b as a novel target of androgen receptor in mouse sertoli cells.
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| Mou L, Zhang Q, Wang Y, Zhang Q, Sun L, Li C, Huang W, Yuan Y, Duan Y, Diao R, Jiang Z, Ye J, Cai Z, Gui Y.
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| Biol Reprod 89(2):32. doi: 10.1095/biolreprod.112.103648. Print 2013 Aug.
2013
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| 4 | UBE2B
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| UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.
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| Yatsenko AN, Georgiadis AP, Murthy LJ, Lamb DJ, Matzuk MM.
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| Mol Hum Reprod 19(6):388-94. doi: 10.1093/molehr/gat008. Epub 2013 Jan 31.
2013
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| 5 | RNF168, UBE2A, UBE2B
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| RNF168 forms a functional complex with RAD6 during the DNA damage response.
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| Liu C, Wang D, Wu J, Keller J, Ma T, Yu X.
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| J Cell Sci 126(Pt 9):2042-51. doi: 10.1242/jcs.122945. Epub 2013 Mar 22.
2013
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| 6 | UBE2A, UBE2B
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| RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms.
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| Chen S, Wang DL, Liu Y, Zhao L, Sun FL.
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| Mol Cell Biol 32(2):576-87. doi: 10.1128/MCB.05966-11. Epub 2011 Nov 14.
2012
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| 7 | UBE2B
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| Genetic association of UBE2B variants with susceptibility to male infertility in a Northeast Chinese population.
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| Hu Y, Wen W, Yu JG, Qu SQ, Wang SS, Liu J, Li BS, Luo Y.
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| Genet Mol Res 11(4):4226-34. doi: 10.4238/2012.September.12.2.
2012
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| 8 | UBE2B
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| Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.
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| Gerard B, Sanders MA, Visscher DW, Tait L, Shekhar MP.
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| Biochim Biophys Acta 1823(10):1686-96. doi: 10.1016/j.bbamcr.2012.05.032. Epub 2012 Jun 15. Erratum in: Biochim Biophys Acta. 2013 May;1833(5):1280-1 2012
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| 9 | RAD18, UBE2B
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| Meiotic functions of RAD18.
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| Inagaki A, Sleddens-Linkels E, Wassenaar E, Ooms M, van Cappellen WA, Hoeijmakers JH, Seibler J, Vogt TF, Shin MK, Grootegoed JA, Baarends WM.
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| J Cell Sci 124(Pt 16):2837-50.
2011
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| 10 | UBE2B
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| E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6.
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| Hibbert RG, Huang A, Boelens R, Sixma TK.
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| Proc Natl Acad Sci U S A 108(14):5590-5. doi: 10.1073/pnas.1017516108. Epub 2011 Mar 21.
2011
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| 11 | UBE2B, UBR1, UBR2
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| UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination.
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| An JY, Kim EA, Jiang Y, Zakrzewska A, Kim DE, Lee MJ, Mook-Jung I, Zhang Y, Kwon YT.
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| Proc Natl Acad Sci U S A 107(5):1912-7. Epub 2010 Jan 11. 2010
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| 12 | UBE2B
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| The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids.
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| Mulugeta Achame E, Wassenaar E, Hoogerbrugge JW, Sleddens-Linkels E, Ooms M, Sun ZW, van IJcken WF, Grootegoed JA, Baarends WM.
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| BMC Genomics 11:367. doi: 10.1186/1471-2164-11-367.
2010
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| 13 | HLTF, UBE2V2, UBE2A, UBE2B, RAD18, UBE2N
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| Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination.
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| Unk I, Hajdś I, F‡tyol K, Hurwitz J, Yoon JH, Prakash L, Prakash S, Haracska L.
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| Proc Natl Acad Sci U S A 105(10):3768-73. Epub 2008 Mar 3. 2008
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| 14 | RAD18, UBE2B
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| Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks.
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| Tsuji Y, Watanabe K, Araki K, Shinohara M, Yamagata Y, Tsurimoto T, Hanaoka F, Yamamura K, Yamaizumi M, Tateishi S.
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| Genes Cells 13(4):343-54. 2008
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| 15 | UBE2B
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| Rad6B is a positive regulator of beta-catenin stabilization.
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| Shekhar MP, Gerard B, Pauley RJ, Williams BO, Tait L.
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| Cancer Res 68(6):1741-50.
2008
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| 16 | UBE2B
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| Novel variants in UBE2B gene and idiopathic male infertility.
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| Suryavathi V, Khattri A, Gopal K, Rani DS, Panneerdoss S, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K.
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| J Androl 29(5):564-71. doi: 10.2164/jandrol.107.004580. Epub 2008 May 22.
2008
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| 17 | UBE2A, UBE2B
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| Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification.
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| Notenboom V, Hibbert RG, van Rossum-Fikkert SE, Olsen JV, Mann M, Sixma TK.
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| Nucleic Acids Res 35(17):5819-30. Epub 2007 Aug 24.
2007
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| 18 | UBE2B
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| The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth.
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| Kavakebi P, Hausott B, Tomasino A, Ingorokva S, Klimaschewski L.
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| Mol Cell Neurosci 29(4):559-68.
2005
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| 19 | UBE2A, UBE2B, RAD18, ZMYM2
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| ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins.
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| Kunapuli P, Somerville R, Still IH, Cowell JK.
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| Oncogene 22(22):3417-23. 2003
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| 20 | UBE2B
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| Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification.
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| Koken MH, Hoogerbrugge JW, Jasper-Dekker I, de Wit J, Willemsen R, Roest HP, Grootegoed JA, Hoeijmakers JH.
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| Dev Biol 173(1):119-32.
1996
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| 21 | UBE2B
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| (CGG) trinucleotide repeat polymorphism in the 5' region of the HHR6B gene : the human homolog of the yeast DNA repair gene RAD6.
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| Lench NJ, et al.
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| Hum Genet 96 : 369-370. 1995
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| 22 | UBE2A, UBE2B
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| Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.
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| Koken MHM, et al.
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| Genomics 12 : 447-453. 1992
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| 23 | UBE2A, UBE2B
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| cDNA cloning of a novel human ubiquitin carrier protein.
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| Liu Z, et al.
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| J Biol Chem 267 : 15829-15835. 1992
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| 24 | UBE2A, UBE2B
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| Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
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| Koken MH, et al.
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| Proc Natl Acad Sci U S A 88 : 8865-8869. 1991
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| 25 | UBE2B
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| The human ubiquitin carrier protein E2(Mr = 17000) is homologous to the yeast DNA repair gene RAD6.
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| Schneider R, et al.
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| EMBO J 9 : 1431-1435. 1990
|