| 1 | SCAR24, UBA5
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| UBA5 Mutations Cause a New Form of Autosomal Recessive Cerebellar Ataxia.
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| Duan R, Shi Y, Yu L, Zhang G, Li J, Lin Y, Guo J, Wang J, Shen L, Jiang H, Wang G, Tang B.
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| PLoS One 11(2):e0149039. doi: 10.1371/journal.pone.0149039. eCollection 2016.
2016
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| 2 | EIEE44, UBA5
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| Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.
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| Muona M, Ishimura R, Laari A, Ichimura Y, Linnankivi T, Keski-Filppula R, Herva R, Rantala H, Paetau A, Pöyhönen M, Obata M, Uemura T, Karhu T, Bizen N, Takebayashi H, McKee S, Parker MJ, Akawi N, McRae J, Hurles ME; DDD Study, Kuismin O, Kurki MI, Anttonen AK, Tanaka K, Palotie A, Waguri S, Lehesjoki AE, Komatsu M.
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| Am J Hum Genet 99(3):683-94. doi: 10.1016/j.ajhg.2016.06.020. Epub 2016 Aug 18.
2016
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| 3 | UBA5, UFM1
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| Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex.
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| Oweis W, Padala P, Hassouna F, Cohen-Kfir E, Gibbs DR, Todd EA, Berndsen CE, Wiener R.
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| Cell Rep 16(12):3113-20. doi: 10.1016/j.celrep.2016.08.067.
2016
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| 4 | EIEE44, UBA5, UFM1
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| Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy.
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| Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D.
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| Am J Hum Genet 99(3):695-703. doi: 10.1016/j.ajhg.2016.06.030. Epub 2016 Aug 18.
2016
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| 5 | UBA5, UFC1, UFM1
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| Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.
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| Habisov S, Huber J, Ichimura Y, Akutsu M, Rogova N, Loehr F, McEwan DG, Johansen T, Dikic I, Doetsch V, Komatsu M, Rogov VV, Kirkin V.
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| J Biol Chem 291(17):9025-41. doi: 10.1074/jbc.M116.715474.
2016
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| 6 | UBA5, UFC1
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| Characterization, crystallization and preliminary X-ray crystallographic analysis of the human Uba5 C-terminus-Ufc1 complex.
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| Xie S.
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| Acta Crystallogr F Struct Biol Commun 70(Pt 8):1093-7. doi: 10.1107/S2053230X14014502. Epub 2014 Jul 23.
2014
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| 7 | UBA5, UFM1
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| Characterization, crystallization and preliminary X-ray crystallographic analysis of the Uba5 fragment necessary for high-efficiency activation of Ufm1.
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| Xie S.
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| Acta Crystallogr F Struct Biol Commun 70(Pt 6):765-8. doi: 10.1107/S2053230X14008826. Epub 2014 May 10.
2014
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| 8 | UBA5, UFM1
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| The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.
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| Tatsumi K, Yamamoto-Mukai H, Shimizu R, Waguri S, Sou YS, Sakamoto A, Taya C, Shitara H, Hara T, Chung CH, Tanaka K, Yamamoto M, Komatsu M.
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| Nat Commun 2:181. doi: 10.1038/ncomms1182.
2011
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| 9 | DDRGK1, UBA5, UFC1, UFL1, UFM1
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| A novel type of E3 ligase for the Ufm1 conjugation system.
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| Tatsumi K, Sou YS, Tada N, Nakamura E, Iemura S, Natsume T, Kang SH, Chung CH, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M.
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| J Biol Chem 285(8):5417-27. Epub 2009 Dec 14.
2010
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| 10 | UBA5, UFM1
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| Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
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| Bacik JP, Walker JR, Ali M, Schimmer AD, Dhe-Paganon S.
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| J Biol Chem 285(26):20273-80. Epub 2010 Apr 5.
2010
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| 11 | UBA5, UFC1, UFM1
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| NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.
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| Liu G, Forouhar F, Eletsky A, Atreya HS, Aramini JM, Xiao R, Huang YJ, Abashidze M, Seetharaman J, Liu J, Rost B, Acton T, Montelione GT, Hunt JF, Szyperski T.
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| J Struct Funct Genomics 10(2):127-36. Epub 2008 Dec 20.
2009
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| 12 | SUMO2, UBA5, UFM1
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| UBE1DC1, an ubiquitin-activating enzyme, activates two different ubiquitin-like proteins.
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| Zheng M, Gu X, Zheng D, Yang Z, Li F, Zhao J, Xie Y, Ji C, Mao Y.
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| J Cell Biochem 104(6):2324-34.
2008
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| 13 | UBA5, UFC1, UFM1
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| Crystal structure of Ufc1, the Ufm1-conjugating enzyme.
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| Mizushima T, Tatsumi K, Ozaki Y, Kawakami T, Suzuki A, Ogasahara K, Komatsu M, Kominami E, Tanaka K, Yamane T.
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| Biochem Biophys Res Commun 362(4):1079-84. Epub 2007 Aug 30.
2007
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| 14 | UBA5, UFC1, UFM1
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| A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
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| Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, Okazaki N, Ueno T, Kominami E, Natsume T, Tanaka K.
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| EMBO J 23(9):1977-86. Epub 2004 Apr 8.
2004
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| 15 | AIF1L, ANKHD1, ANKRD20A1, ANKRD27, ANKRD32, APH1B, APOLD1, ARMC4, ATXN10, C10orf10, C10orf10, C10orf118, C2orf14, C2orf16, C6orf60, C6orf62, C8orf71, CALCOCO1, CAMKK1, CCDC113, CCDC135, CCDC9, CCDC90B, CCNB2, CD99L2, CHPF, CLIC4, CLPB, CRELD1, CYBRD1, DDX47, DHRS7B, ESPN, FIP1L1, FLYWCH1, FYTTD1, GABARAPL1, GOLT1B, GPS2, GRIPAP1, HIGD1A, IER3IP1, KIF18A, KIRREL2, KLC2, LHX6, LMAN2L, MAF1, MED23, MIS12, MOB4, MYCBPAP, NCALD, NELF, NELFB, NRBF2, NRIP2, NRIP2, NRSN2, NUDT12, PCBD2, PMFBP1, PRPF31, PRSS23, QRSL1, RGMA, RGMB, RNF123, RNF146, RWDD3, SAMHD1, SECISBP2, SEMA4F, SERBP1, SERP1, SH3BP5L, SLC25A24, SLC25A39, SLC37A3, SLC41A2, SLC6A16, SMC6, SPEF1, STMN2, TARDBP, TBC1D3, TBL2, TFIP11, TIGD6, TIMMDC1, TMEM117, TMEM186, TNB, TRAF7, TRAPPC8, TSC22D3, TSPAN14, TWF2, UBA5, UNC50, WDR24, WDR37, WDR91, WSB1, YIPF3, ZC3H13, ZMYND12, ZMYND15, ZRANB3
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| Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
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| Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A.
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| Genome Res 11(3):422-35. 2001
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