1 | UBA1, UBD
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| Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.
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| Bialas J, Groettrup M, Aichem A.
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| PLoS One 10(3):e0120329. doi: 10.1371/journal.pone.0120329. eCollection 2015.
2015
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2 | FUS, PSMD12, SFPQ, UBA1, VCP
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| Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.
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| Wang T, Jiang X, Chen G, Xu J.
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| Neurobiol Aging 36(1):527-35. doi: 10.1016/j.neurobiolaging.2014.07.044.
2015
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3 | UBA1, UBTD2, USP5
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| A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes
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| Song AX, Yang H, Gao YG, Zhou CJ, Zhang YH, Hu HY
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| PLoS One. Sep 10;9(9):e107509. doi: 10.1371/journal.pone.0107509. 2014
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4 | UBA1
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| The functional role of UBA1 cysteine-278 in ubiquitination.
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| Yang U, Yang HY, Kim JS, Lee TH.
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| Biochem Biophys Res Commun 427(3):587-92. doi: 10.1016/j.bbrc.2012.09.102. Epub 2012 Sep 26.
2012
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5 | UBA1, UBA6, USE1
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| Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.
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| Lee PC, Sowa ME, Gygi SP, Harper JW.
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| Mol Cell. 43(3):392-405. 2011
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6 | UBA1, SMAX
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| Rare missense and synonymous variants in UBE1 are associated with X-linked infantile spinal muscular atrophy.
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| Ramser J, Ahearn ME, Lenski C, Yariz KO, Hellebrand H, von Rhein M, Clark RD, Schmutzler RK, Lichtner P, Hoffman EP, Meindl A, Baumbach-Reardon L.
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| Am J Hum Genet 82(1):188-93. 2008
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7 | UBA1, UBA6
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| Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.
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| Jin J, Li X, Gygi SP, Harper JW.
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| Nature 447(7148):1135-8. 2007
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8 | TKTL1, FTHL17, UBA1, TAF7L, USP26, NXF2, TEX13A, TEX13B, TEX11
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| Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.
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| Wang PJ, Page DC, McCarrey JR.
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| Hum Mol Genet 14(19):2911-8. Epub 2005 Aug 23. 2005
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9 | CFL1, UBA1
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| Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems.
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| Saito Y, Doi K, Yamagishi N, Ishihara K, Hatayama T.
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| Biochem Biophys Res Commun. 314(2):396-402. 2004
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10 | UBA1
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| Physical map covering a 2 Mb region in human xp11.3 distal to DX6849.
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| Stoddart KL, et al.
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| Gene 227(1):111-6. 1999
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11 | CDK16, UBA1
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| X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse.
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| Carrel L, Clemson CM, Dunn JM, Miller AP, Hunt PA, Lawrence JB, Willard HF.
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| Hum Mol Genet 5(3):391-401. 1996
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12 | RBM10, UBA1
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| A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status.
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| Coleman MP, Ambrose HJ, Carrel L, Nemeth AH, Willard HF, Davies KE.
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| Genomics 31(1):135-8. 1996
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13 | CDK16, UBA1
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| Physical linkage of the cdc2-related gene (PCTK1) and the ubiquitin-activating enzyme E1 gene (UBE1) on human Xp11.3.
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| Knight JC, Renwick PJ, Downing JR, Okuda T.
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| Cytogenet Cell Genet 71(2):155-7. 1995
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14 | UBA1
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| Ubiquitin-activating enzyme, E1, is phosphorylated in mammalian cells by the protein kinase Cdc2.
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| Nagai Y, Kaneda S, Nomura K, Yasuda H, Seno T, Yamao F.
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| J Cell Sci. 7673335 1995
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15 | UBA1
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| The human ubiquitin-activating enzyme E1 gene (UBE1) mapped to band Xp11.3-p11.23 by fluorescence in situ hybridization.
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| Takahashi E, et al.
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| Cytogenet Cell Genet 59 : 268-269. 1992
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16 | UBA1
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| Human ubiquitin-activating enzyme (E1) : compensation for heat-labile mouse E1 and its gene localization on the X chromosome.
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| Kudo M, et al.
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| Exp Cell Res 192 : 110-117. 1991
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17 | UBA1
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| Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.
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| Handley PM, et al.
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| Proc Natl Acad Sci U S A 88 : 258-262. 1991
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18 | UBA1
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| A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1.
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| Kay GF, et al.
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| Nature 354 : 486-489. 1991
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19 | UBA1
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| Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1.
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| Mitchell MJ, et al.
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| Nature 354 : 483-486. 1991
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20 | UBA1
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| Localization of the human A1S9 gene complementing the ts A1S9 mouse L-cell defect in DNA replication and cell cycle progression to Xp11.2-p11.4.
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| Zacksenhaus E, et al.
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| Cytogenet Cell Genet 53 : 20-22. 1990
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21 | UBA1
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| Localization of a gene that escapes inactivation to the X chromosome proximal short arm: implications for X inactivation.
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| Brown CJ, Willard HF.
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| Am J Hum Genet 46(2):273-9. 1990
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22 | UBA1
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| Gene on short arm of human X chromosome complements murine tsA1S9 DNA synthesis mutation.
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| Brown CJ, et al.
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| Somat Cell Mol Genet 15 : 173-178. 1989
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23 | UBA1
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| Noninactivation of a selectable human X-linked gene that complements a murine temperature-sensitive cell cycle defect.
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| Brown CJ, et al.
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| Am J Hum Genet 45 : 592-598. 1989
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24 | UBA1
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| Molecular cloning of human A1S9 locus: an X-linked gene essential for progression through S phase of the cell cycle.
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| Zacksenhaus E, Sheinin R.
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| Somat Cell Mol Genet 15 : 545-553. 1989
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25 | UBA1
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| The gene coding A ubiquitin-activating enzyme may locate on X chromosome.
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| Ohtsubo M, et al.
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| Biochem Biophys Res Commun 153 : 1173-1178. 1988
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26 | UBA1
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| Identification of a gene on the short arm of the X chromosome that complements a mouse temperature-sensitive defect in DNA synthesis.
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| Willard HF, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 716. 1987
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