| 1 | JMJD6, U2AF2
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| JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner.
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| Yi J, Shen HF, Qiu JS, Huang MF, Zhang WJ, Ding JC, Zhu XY, Zhou Y, Fu XD, Liu W.
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| Nucleic Acids Res 45(6):3503-3518. doi: 10.1093/nar/gkw1144.
2017
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| 2 | PRPF40B, SF1, U2AF2
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| Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo.
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| Becerra S, Montes M, Hernández-Munain C, Suñé C.
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| RNA 21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20.
2015
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| 3 | SMN1, SMN2, SNRNPM, U2AF2
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| hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.
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| Cho S, Moon H, Loh TJ, Oh HK, Cho S, Choy HE, Song WK, Chun JS, Zheng X, Shen H.
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| Biochim Biophys Acta 1839(4):306-15. doi: 10.1016/j.bbagrm.2014.02.006. Epub 2014 Feb 15.
2014
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| 4 | TERF1, U2AF2
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| The splicing factor U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis.
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| Kim J, Chung IK.
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| Biochem Biophys Res Commun 443(3):1124-30. doi: 10.1016/j.bbrc.2013.12.118. Epub 2013 Dec 31.
2014
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| 5 | SF1, U2AF2
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| Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex.
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| Wang W, Maucuer A, Gupta A, Manceau V, Thickman KR, Bauer WJ, Kennedy SD, Wedekind JE, Green MR, Kielkopf CL.
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| Structure 21(2):197-208. doi: 10.1016/j.str.2012.10.020. Epub 2012 Dec 27.
2013
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| 6 | FLT1, JMJD6, U2AF2
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| Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1.
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| Boeckel JN, Guarani V, Koyanagi M, Roexe T, Lengeling A, Schermuly RT, Gellert P, Braun T, Zeiher A, Dimmeler S.
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| Proc Natl Acad Sci U S A 108(8):3276-81. Epub 2011 Feb 7.
2011
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| 7 | SF1, U2AF2
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| RNA induces conformational changes in the SF1/U2AF65 splicing factor complex.
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| Gupta A, Jenkins JL, Kielkopf CL.
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| J Mol Biol 405(5):1128-38. Epub 2010 Dec 10.
2011
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| 8 | PRPF19, U2AF2
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| The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex.
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| David CJ, Boyne AR, Millhouse SR, Manley JL.
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| Genes Dev 25(9):972-83.
2011
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| 9 | U2AF2
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| Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.
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| Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M.
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| Nature 475(7356):408-11. doi: 10.1038/nature10171.
2011
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| 10 | NXF1, U2AF2
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| Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA toxicity in polyQ diseases.
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| Tsoi H, Lau CK, Lau KF, Chan HY.
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| Hum Mol Genet 20(19):3787-97. Epub 2011 Jul 1.
2011
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| 11 | ATXN1, RBM17, U2AF2
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| 14-3-3 Binding to ataxin-1(ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus.
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| Lai S, O'Callaghan B, Zoghbi HY, Orr HT.
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| J Biol Chem 286(40):34606-16. Epub 2011 Aug 11.
2011
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| 12 | SF3B1, SRSF1, SRSF2, U2AF1, U2AF2, ZRSR2
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| Frequent pathway mutations of splicing machinery in myelodysplasia.
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| Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R, Sato Y, Sato-Otsubo A, Kon A, Nagasaki M, Chalkidis G, Suzuki Y, Shiosaka M, Kawahata R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Ishiyama K, Mori H, Nolte F, Hofmann WK, Miyawaki S, Sugano S, Haferlach C, Koeffler HP, Shih LY, Haferlach T, Chiba S, Nakauchi H, Miyano S, Ogawa S.
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| Nature 478(7367):64-9. doi: 10.1038/nature10496.
2011
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| 13 | U2AF2
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| A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo.
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| Chen C, Zhao X, Kierzek R, Yu YT.
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| Mol Cell Biol 30(17):4108-19. Epub 2010 Jul 6.
2010
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| 14 | PUF60, U2AF2
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| Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
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| Corsini L, Hothorn M, Stier G, Rybin V, Scheffzek K, Gibson TJ, Sattler M.
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| J Biol Chem 284(1):630-9. Epub 2008 Oct 29.
2009
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| 15 | JMJD6, U2AF2
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| Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.
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| Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, Nielsen ML, Schmitz C, Butler DS, Yates JR 3rd, Delahunty CM, Hahn P, Lengeling A, Mann M, Proudfoot NJ, Schofield CJ, Böttger A.
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| Science 325(5936):90-3.
2009
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| 16 | MBNL1, U2AF2
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| The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing.
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| Warf MB, Diegel JV, von Hippel PH, Berglund JA.
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| Proc Natl Acad Sci U S A 106(23):9203-8. Epub 2009 May 26.
2009
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| 17 | RBM39, U2AF2, ZC3H11A
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| Interactome for auxiliary splicing factor U2AF(65) suggests diverse roles.
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| Prigge JR, Iverson SV, Siders AM, Schmidt EE.
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| Biochim Biophys Acta 1789(6-8):487-92. doi: 10.1016/j.bbagrm.2009.06.002. Epub 2009 Jun 18.
2009
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| 18 | U2AF2
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| Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65.
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| Jenkins JL, Shen H, Green MR, Kielkopf CL.
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| J Biol Chem 283(48):33641-9. Epub 2008 Oct 8.
2008
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| 19 | SF1, U2AF1, U2AF2
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| Splicing factors SF1 and U2AF associate in extraspliceosomal complexes.
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| Rino J, Desterro JM, Pacheco TR, Gadella TW Jr, Carmo-Fonseca M.
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| Mol Cell Biol 28(9):3045-57. Epub 2008 Feb 19. 2008
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| 20 | U2AF2
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| Fas splicing regulation during early apoptosis is linked to caspase-mediated cleavage of U2AF65.
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| Izquierdo JM.
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| Mol Biol Cell 19(8):3299-307. Epub 2008 May 28.
2008
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| 21 | SF1, U2AF2
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| Splicing factors SF1 and U2AF associate in extraspliceosomal complexes.
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| Rino J, Desterro JM, Pacheco TR, Gadella TW Jr, Carmo-Fonseca M.
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| Mol Cell Biol 28(9):3045-57. Epub 2008 Feb 19.
2008
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| 22 | U2AF2
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| Alternative conformations at the RNA-binding surface of the N-terminal U2AF(65) RNA recognition motif.
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| Thickman KR, Sickmier EA, Kielkopf CL.
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| J Mol Biol 366(3):703-10. Epub 2006 Dec 2.
2007
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| 23 | CPSF6, U2AF2
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| An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries.
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| Millevoi S, Loulergue C, Dettwiler S, Karaa SZ, Keller W, Antoniou M, Vagner S.
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| EMBO J 25(20):4854-64. Epub 2006 Oct 5.
2006
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| 24 | U2AF1, U2AF2
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| In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site.
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| Pacheco TR, Coelho MB, Desterro JM, Mollet I, Carmo-Fonseca M.
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| Mol Cell Biol 26(21):8183-90. Epub 2006 Aug 28.
2006
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| 25 | SF1, U2AF2, U2AF1
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| Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.
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| Selenko P, Gregorovic G, Sprangers R, Stier G, Rhani Z, Kramer A, Sattler M.
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| Mol Cell 11(4):965-76. 2003
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| 26 | U2AF1, U2AF2, U2AF1L4
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| Characterization of U2AF(6), a splicing factor related to U2AF(35).
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| Shepard J, Reick M, Olson S, Graveley BR.
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| Mol Cell Biol 22(1):221-30. 2002
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| 27 | U2AF2
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| The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.
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| Zuo P, Maniatis T.
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| Genes Dev 10(11):1356-68. 1996
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| 28 | U2AF2, U2AF2
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| Cloning and domain structure of the mammalian splicing factor U2AF.
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| Zamore PD, Patton JG, Green MR.
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| Nature 355(6361):609-14. 1992
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| 29 | U2AF2
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| Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution.
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| Zamore PD, Green MR.
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| EMBO J 10(1):207-14. 1991
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